4 recruiting. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 4 |
| Phase 1 | 1 | Recruiting 1 |
Follow Sickle Cell Anemia: new trials by email Literature Review of Sickle Cell Anemia trials Research Report on Sickle Cell Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype Senicapoc, Placebo - Sickle Cell Disease, Sickle Cell Anaemia | Phase 2 | Recruiting | Biossil Inc. | 105 | 2026-08-13 | 2026-08-17 |
| Alendronate for Osteonecrosis in Adults With Sickle Cell Disease Alendronate Sodium - Sickle Cell Disease, Sickle Cell Anemia | Phase 2 | Recruiting | University of California, Davis | 30 | 2026-03-09 | 2026-07-16 |
| A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD TCRα/β+ and CD19+ depleted haploidentical stem cell transplantation, Matched sibling donor transplantation - HbS Disease, Hemoglobin S Disease | Phase 2 | Recruiting | University of Regensburg | 212 | 2021-06-30 | 2024-05-13 |
| T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea - Sickle Cell Anemia, Beta-thalassemia Major | Phase 1 / Phase 2 | Recruiting | Paul Szabolcs | 5 | 2018-08-02 | 2026-08-13 |
Anemia, Sickle Cell (4) · Anemia (2) · Anemia, Diamond-Blackfan (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Hemoglobinopathies (1) · Legg-Calve-Perthes Disease (1) · Osteonecrosis (1) · beta-Thalassemia (1)
Anemia, Hemolytic (3) · Anemia, Hemolytic, Congenital (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Hemoglobinopathies (3) · Anemia (2) · Anemia, Aplastic (1) · Anemia, Hypoplastic, Congenital (1) · Bone Diseases (1) · Bone Marrow Diseases (1) · Bone Marrow Failure Disorders (1) · Congenital Bone Marrow Failure Syndromes (1) · Femur Head Necrosis (1)
Alemtuzumab (1) · Alendronate (1) · Hydroxyurea (1) · Rituximab (1) · Thiotepa (1) · fludarabine (1) · fludarabine phosphate (1) · senicapoc (1)
Biossil Inc. (1) · Paul Szabolcs (1) · University of California, Davis (1) · University of Regensburg (1)
United States (2) · Austria (1) · Canada (1) · Germany (1)
Oyebimpe O Adesina, MD, MS (1) · Paul Szabolcs, MD (1) · Selim Corbacioglu, MD (1)
K23HL148310 (1)