17 completed, 2 withdrawn, 1 unknown. 17 Not applicable, 2 Early Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 14, Withdrawn 2, Unknown 1 |
| Early Phase 1 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow Rhytides: new trials by email Literature Review of Rhytides trials Research Report on Rhytides
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy & Safety of hADM Skin Booster Elravie Re2O, Elravie Balance - Rhytides, Skin Texture Irregularities | Phase 4 | Completed | Yonsei University | 20 | 2024-11-21 | 2025-09-04 |
| Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment ellacor® Micro-Coring procedure - Wrinkle, Rhytides | Not applicable | Completed | Cytrellis Biosystems, Inc. | 3 | 2024-04-30 | 2024-07-16 |
| Safety and Efficacy of SofWave Treatment to Lift the Upper Lip and Improve the Peri-Oral Rhytids Sofwave - Rhytides, Wrinkle | Not applicable | Completed | Sofwave Medical LTD | 60 | 2023-07-01 | 2025-05-15 |
| Effective OnabotulinumtoxinA Dose Response Study for Upper Facial Wrinkles OnabotulinumtoxinA Standard Dose, OnabotulinumtoxinA Half Standard Dose - Rhytides | Not applicable | Withdrawn | Northwell Health | 2023-05-25 | 2023-10-16 | |
| Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA - Rhytides | Early Phase 1 | Completed | Lupo Center for Aesthetic and General Dermatology | 10 | 2023-05-01 | 2024-03-13 |
| Open Label Study Exploring Tissue Histopathology After Ellacor® Procedure in an Abdominoplasty Model. ellacor® Micro-Coring procedure - Histopathology, Wrinkle | Not applicable | Completed | Cytrellis Biosystems, Inc. | 6 | 2023-02-22 | 2024-05-20 |
| BCT-HA Kit for Dehydrated and Wrinkled Skin Cellular Matrix TM BCT-HA Kit (ref. BCT-HA-3), PRP Only, Placebo - Rhytides, Wrinkle | Early Phase 1 | Completed | University of Minnesota | 15 | 2022-06-10 | 2024-04-29 |
| Split-face Study: Cosmetic Botulinum Toxin Type A Injection Under Electromyography-guidance Versus Conventional Palpation Technique Electromyography-Needle Intramuscular Drug guidance, Botulinum toxin type A - Glabellar Frown Lines, Rhytides | Not applicable | Completed | Mohamed Hayder Oleish Salih | 15 | 2021-08-09 | 2022-08-26 |
| Restylane Refyne for Correction of Horizontal Neck Rhytides Restylane Refyne - Aging, Wrinkle | Not applicable | Completed | Siperstein Dermatology | 26 | 2020-08-11 | 2026-07-16 |
| Renuvion Dermal System for Dermal Resurfacing Renuvion Dermal System - Wrinkle, Rhytides | Not applicable | Completed | Apyx Medical | 55 | 2019-12-30 | 2022-06-22 |
| Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle - Photoaging, Hyperpigmentation | Not applicable | Completed | Integrative Skin Science and Research | 19 | 2019-09-10 | 2020-10-14 |
| Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles Venus Viva - Rhytides, Wrinkle | Not applicable | Completed | Venus Concept | 25 | 2019-03-08 | 2023-08-15 |
| The Cosmetic Effect of Mineral Clay Masks Clay mask - Rhytides | Not applicable | Completed | University of California, Davis | 41 | 2019-01-01 | 2021-09-13 |
| Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles Venus Viva - Rhytides, Wrinkle | Not applicable | Completed | Venus Concept | 15 | 2018-12-12 | 2023-09-06 |
| The Use of J-Plasma® for Dermal Resurfacing J-Plasma - Facial Wrinkles, Rhytides | Not applicable | Completed | Apyx Medical | 55 | 2018-01-22 | 2022-07-27 |
| The Effect of Almonds on Skin Lipids and Wrinkles Almonds - Rhytides | Not applicable | Completed | University of California, Davis | 31 | 2016-10-25 | 2018-10-17 |
| TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides TriActive+ RF - Wrinkles, Rhytides | Not applicable | Completed | El. En. SpA | 51 | 2013-05-01 | 2015-04-07 |
| TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides TriActive+ RF - Wrinkles, Rhytides | Not applicable | Completed | Deka Medical, Inc. | 25 | 2011-10-01 | 2014-07-04 |
| Enhanced Safety Aesthetic Laser System Peterio - Hirsutism, Hypertrichosis | Not applicable | Unknown | Scilex Ltd. | 25 | 2007-09-01 | 2007-07-03 |
| Comparison of AmnioFix Laser and Standard of Care Treatment AmnioFix plus Standard of Care, Standard of Care - Rhytides | Not applicable | Withdrawn | University of California, San Francisco | 2022-03-21 |
Facial Expression (1) · Hirsutism (1) · Hyperpigmentation (1) · Hypertrichosis (1) · Lymphoid Interstitial Pneumonia (1) · Telangiectasis (1)
Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Behavior (1) · Cardiovascular Diseases (1) · Communication (1) · Hair Diseases (1) · Nonverbal Communication (1) · Pathological Conditions, Signs and Symptoms (1) · Pigmentation Disorders (1) · Signs and Symptoms (1) · Vascular Diseases (1) · Virilism (1)
Botulinum Toxins, Type A (3) · Botulinum Toxins (1) · Standard of Care (1) · incobotulinumtoxinA (1) · prabotulinumtoxin A (1)
Apyx Medical (2) · Cytrellis Biosystems, Inc. (2) · University of California, Davis (2) · Venus Concept (2) · Deka Medical, Inc. (1) · El. En. SpA (1) · Integrative Skin Science and Research (1) · Lupo Center for Aesthetic and General Dermatology (1) · Mohamed Hayder Oleish Salih (1) · Northwell Health (1) · Scilex Ltd. (1) · Siperstein Dermatology (1) · Sofwave Medical LTD (1) · University of California, San Francisco (1) · University of Minnesota (1)
United States (16) · Egypt (1) · Israel (1) · South Korea (1)
Matthew Gronski (2) · Alessandro Bizzari, ElEn (1) · Allen Gabriel, MD (1) · Cindy Ponce, BS(ACS) (1) · Edward Zimmerman, MD (1) · Jill Edgecombe (1) · Ju Hee Lee, M.D., Ph.D. (1) · Leon Gilad, MD (1) · Maria Hordinsky, MD (1) · Mohamed H Oleish, MB BCh (1) · Nicholas Bastidas, MD (1) · Raja K Sivamani, M.D. (1) · Raja K Sivamani, MD (1) · Rod Rohrich, MD (1)