10 completed. 10 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 10 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 1 | Completed 1 |
Follow Relapse: new trials by email Literature Review of Relapse trials Research Report on Relapse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT donor lymphocyte infusion - Minimal Residual Disease, Donor Lymphocyte Infusion | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 206 | 2016-01-01 | 2020-02-25 |
| Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies Carfilzomib, Tacrolimus - Hematologic Malignancies, Relapse | Phase 1 / Phase 2 | Completed | University of Michigan Rogel Cancer Center | 53 | 2014-10-01 | 2022-01-03 |
| Efficacy of Lenalidomide With Rituximab in Refractory or Relapse of Primary Central Nervous System Lymphoma Lenalidomide, Rituximab - Lymphoma, Relapse | Phase 2 | Completed | Institut Curie | 45 | 2013-09-18 | 2020-12-17 |
| Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence Naltrexone, Placebo - Major Depressive Disorder, Depression, Unipolar | Phase 2 | Completed | Massachusetts General Hospital | 12 | 2013-06-01 | 2017-02-24 |
| Cord Blood Transplantation in Severe Aplastic Anemia Cord Blood Transplantation - Hereditary Diseases, Acquired Aplastic Anemia | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 26 | 2011-05-01 | 2017-06-15 |
| Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma PET, MRI imaging - Thyroid Cancer, Relapse | Phase 2 | Completed | Centre Henri Becquerel | 37 | 2011-03-01 | 2016-08-24 |
| A Trial Evaluating Efficacy and Safety of Oxaliplatin With 5-Fluorouracil in Patients With Recurrent Ovarian Carcinoma Oxaliplatin, oxaliplatin - Ovarian Carcinoma, Relapse | Phase 2 | Completed | Jules Bordet Institute | 90 | 2008-10-01 | 2014-10-15 |
| Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion donor lymphocyte infusion - Hematologic Neoplasms, Relapse | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 21 | 2005-12-01 | 2011-01-24 |
| Evaluation of Lenalidomide, Doxorubicin and Dexamethasone (RAD) in Patients With Relapsed or Refractory Multiple Myeloma Revlimid - Relapse, Refractory Multiple Myeloma | Phase 1 / Phase 2 | Completed | University of Wuerzburg | 53 | 2004-09-01 | 2009-08-04 |
| A Japan Phase I/II Study of Bortezomib in Relapsed or Refractory Multiple Myeloma Patients bortezomib - Refractory, Multiple Myeloma | Phase 1 / Phase 2 | Completed | Janssen Pharmaceutical K.K. | 35 | 2004-05-01 | 2011-05-17 |
Recurrence (10) · Multiple Myeloma (3) · Hematologic Neoplasms (2) · Lymphoma (2) · Anemia, Aplastic (1) · Depression (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Genetic Diseases, Inborn (1) · Graft vs Host Disease (1) · Leukemia (1) · Neoplasm, Residual (1) · Ovarian Neoplasms (1) · Thyroid Neoplasms (1)
Disease Attributes (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Neoplasms (8) · Hemic and Lymphatic Diseases (6) · Hematologic Diseases (5) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Lymphoproliferative Disorders (4) · Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Blood Protein Disorders (3) · Cardiovascular Diseases (3) · Hemorrhagic Disorders (3) · Hemostatic Disorders (3)
Lenalidomide (2) · Bortezomib (1) · Cord Blood Stem Cell Transplantation (1) · Naltrexone (1) · Oxaliplatin (1) · Rituximab (1) · Tacrolimus (1) · carfilzomib (1)
Assistance Publique - Hôpitaux de Paris (2) · Centre Henri Becquerel (1) · Institut Curie (1) · Janssen Pharmaceutical K.K. (1) · Jules Bordet Institute (1) · Massachusetts General Hospital (1) · Nanfang Hospital, Southern Medical University (1) · University of Michigan Rogel Cancer Center (1) · University of Wuerzburg (1)
France (4) · United States (2) · Belgium (1) · China (1) · Germany (1)
Attaphol Pawarode, M.D. (1) · David Mischoulon, M.D. (1) · Pierre Vera, MD, PhD (1) · Qifa Liu (1) · Ralf Bargou, MD (1) · Veronique D'Hondt, MD,PhD (1)
PMID 19182205, PMID 20650872, PMID 27736689, PMID 29760162, PMID 30698644, PMID 32164760, PMID 35467818