3 recruiting, 2 completed, 1 active not recruiting, 1 not yet recruiting. 9 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Recruiting 3, Completed 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Recurrent Glioma: new trials by email Literature Review of Recurrent Glioma trials Research Report on Recurrent Glioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations Vorasidenib, Lomustine - Recurrent Glioma, IDH-mutant Gliomas | Phase 1 | Not yet recruiting | Megan Mantica | 36 | 2026-11-30 | 2026-10-22 |
| Sitagliptin in Recurrent/Progressive Grade 4 Glioma Sitagliptin, Bevacizumab - Glioma, Glioblastoma | Phase 1 | Recruiting | Kailin Yang, MD, PhD | 45 | 2026-06-11 | 2026-06-17 |
| CARv3-TEAM-E T Cells in Glioblastoma CARv3-TEAM-E T cells - Glioblastoma, Malignant Glioma | Phase 1 | Recruiting | Marcela V. Maus, M.D.,Ph.D. | 21 | 2023-03-22 | 2026-07-14 |
| Personalized Vaccine for Patients With Recurrent Malignant Glioma personalized vaccine - Malignant Glioma, Recurrent Glioma | Phase 1 | Unknown | Xuanwu Hospital, Beijing | 10 | 2021-07-15 | 2021-06-29 |
| A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors GNC-039 - Recurrent Glioma, Solid Tumor | Phase 1 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 60 | 2021-04-14 | 2026-08-27 |
| A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas PRT811 - Advanced Solid Tumor, Recurrent Glioma | Phase 1 | Completed | Prelude Therapeutics Incorporated | 86 | 2019-11-06 | 2023-04-05 |
| Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma HER2(EQ)BBζ/CD19t+ T cells, Laboratory Biomarker Analysis, Leukapheresis - Glioblastoma, Malignant Glioma | Phase 1 | Active not recruiting | City of Hope Medical Center | 29 | 2018-08-14 | 2026-02-04 |
| Repeat Radiation, Minocycline and Bevacizumab in Patients With Recurrent Glioma Bevacizumab, Minocycline, Radiation - Recurrent Glioma | Phase 1 / Phase 2 | Completed | University of Utah | 22 | 2012-07-06 | 2019-08-16 |
| Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors Panobinostat, Stereotactic body radiation therapy, Quality-of-life assessment - Recurrent Glioma, High-grade Meningioma | Phase 1 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 17 | 2012-05-01 | 2025-05-02 |
Glioma (9) · Glioblastoma (3) · Brain Neoplasms (1) · Meningioma (1)
Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Germ Cell and Embryonal (9) · Neoplasms, Glandular and Epithelial (9) · Neoplasms, Nerve Tissue (9) · Neoplasms, Neuroepithelial (9) · Neuroectodermal Tumors (9) · Astrocytoma (3) · Brain Diseases (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Meningeal Neoplasms (1) · Neoplasms by Site (1) · Neoplasms, Vascular Tissue (1) · Nervous System Diseases (1)
Bevacizumab (2) · Leukapheresis (1) · Lomustine (1) · Minocycline (1) · Panobinostat (1) · Radiation (1) · Radiosurgery (1) · Sitagliptin Phosphate (1) · vorasidenib (1)
City of Hope Medical Center (1) · Kailin Yang, MD, PhD (1) · Marcela V. Maus, M.D.,Ph.D. (1) · Megan Mantica (1) · Prelude Therapeutics Incorporated (1) · Sichuan Baili Pharmaceutical Co., Ltd. (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · University of Utah (1) · Xuanwu Hospital, Beijing (1)
United States (7) · China (2)
Adam Cohen, MD (1) · Behnam Badie (1) · Kailin Yang, MD, PhD (1) · Megan Mantica, MD (1) · Wenbin Li (1) · Wenyin Shi, MD, PhD (1) · William Curry, MD (1)
P30CA033572 (1)