6 completed. 6 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
Follow Pseudoxanthoma Elasticum: new trials by email Literature Review of Pseudoxanthoma Elasticum trials Research Report on Pseudoxanthoma Elasticum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum DS-1211b, Placebo - Pseudoxanthoma Elasticum | Phase 2 | Completed | Daiichi Sankyo | 65 | 2022-10-20 | 2024-12-31 |
| Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ABCC6 Deficiency Causing PXE INZ-701 - ATP-Binding Cassette Subfamily C Member 6 Deficiency, Pseudoxanthoma Elasticum | Phase 1 / Phase 2 | Completed | Inozyme Pharma | 10 | 2022-04-11 | 2026-10-13 |
| Intravitreal Aflibercept for Therapy of Patients With Pseudoxanthoma Elasticum (PXE) Aflibercept - Pseudoxanthoma Elasticum | Phase 2 | Completed | University Hospital, Bonn | 15 | 2015-09-01 | 2019-05-07 |
| Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE) Magnesium Oxide, Placebo - Pseudoxanthoma Elasticum | Phase 2 | Completed | Mark Lebwohl | 44 | 2012-08-01 | 2021-03-10 |
| Ranibizumab to Treat Choroidal Neovascularization (CNV) in Patients With Pseudoxanthoma Elasticum (PXE) Intravitreal injection ranibizumab - Choroidal Neovascularization | Phase 2 | Completed | University Hospital, Bonn | 10 | 2007-08-01 | 2012-06-15 |
| Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy ranibizumab injection (0.5 mg) - Coats' Disease, Idiopathic Retinal Telangiectasia | Phase 1 / Phase 2 | Completed | Manhattan Eye, Ear & Throat Hospital | 18 | 2007-05-01 | 2012-10-25 |
Angioid Streaks (2) · Choroidal Neovascularization (2) · Arterial calcification of infancy (1) · Calcinosis (1) · Myopia, Degenerative (1) · Polypoidal Choroidal Vasculopathy (1) · Retinal Telangiectasis (1) · Vitelliform Macular Dystrophy (1) · von Hippel-Lindau Disease (1)
Cardiovascular Diseases (6) · Congenital Abnormalities (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Connective Tissue Diseases (6) · Genetic Diseases, Inborn (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Hemorrhagic Disorders (6) · Hemostatic Disorders (6) · Skin Abnormalities (6) · Skin Diseases (6) · Skin Diseases, Genetic (6) · Skin and Connective Tissue Diseases (6) · Vascular Diseases (6) · Choroid Diseases (3)
Ranibizumab (2) · Magnesium Oxide (1) · aflibercept (1)
University Hospital, Bonn (2) · Daiichi Sankyo (1) · Inozyme Pharma (1) · Manhattan Eye, Ear & Throat Hospital (1) · Mark Lebwohl (1)
United States (4) · Germany (2) · Netherlands (1) · United Kingdom (1)
Frank G. Holz, MD (1) · Frank G. Holz, MD, DPhil (1) · Hendrik PN Scholl, MD, MA (1) · Lawrence A. Yannuzzi, MD (1) · Mark Lebwohl, MD (1)