5 recruiting, 3 completed, 1 not yet recruiting, 1 unknown. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Vitelliform Macular Dystrophy: new trials by email Literature Review of Vitelliform Macular Dystrophy trials Research Report on Vitelliform Macular Dystrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wide Field OCTA in Ocular Diseases Age - Related Macular Degeneration (AMD), Diabetic Macular Edema | Not yet recruiting | IRCCS San Raffaele | 200 | 2026-01-01 | 2025-12-30 | |
| Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB) OPGx-BEST1 - ARB, BVMD | Phase 1 / Phase 2 | Recruiting | Opus Genetics, Inc | 10 | 2025-09-25 | 2026-09-24 |
| National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases Inherited Ophthalmic Diseases, Hypopigmentation Disorder | Recruiting | National Eye Institute (NEI) | 1000 | 2024-07-12 | 2026-06-09 | |
| Structural and Functional Characterization of Rare Ocular Diseases Retinitis Pigmentosa, Stargardt Disease 1 | Unknown | Barcelona Macula Foundation | 50 | 2021-11-24 | 2022-03-15 | |
| Study of BEST1 Vitelliform Macular Dystrophy Natural History Study - Best Vitelliform Macular Dystrophy, Retinitis Pigmentosa | Recruiting | Columbia University | 52 | 2021-03-30 | 2025-07-30 | |
| Sildenafil for Treatment of Choroidal Ischemia Sildenafil, Standard of Care Sildenafil, Ocular Coherence Tomography-Angiography (OCT-A) - Choroidal Ischemia, Vitelliform Macular Dystrophy | Phase 2 | Completed | Columbia University | 22 | 2014-11-11 | 2025-07-04 |
| Inherited Retinal Degenerative Disease Registry Eye Diseases Hereditary, Retinal Disease | Recruiting | Foundation Fighting Blindness | 20000 | 2014-06-01 | 2026-05-19 | |
| Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases. Retinal Disease, Bestrophinopathy | Completed | Mayo Clinic | 48 | 2014-02-01 | 2023-01-09 | |
| Cell Collection to Study Eye Diseases Retinal Disease, AMD | Recruiting | National Eye Institute (NEI) | 930 | 2011-09-07 | 2026-09-22 | |
| Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy ranibizumab injection (0.5 mg) - Coats' Disease, Idiopathic Retinal Telangiectasia | Phase 1 / Phase 2 | Completed | Manhattan Eye, Ear & Throat Hospital | 18 | 2007-05-01 | 2012-10-25 |
Retinitis Pigmentosa (6) · Retinal Diseases (4) · Macular Degeneration (3) · Stargardt Disease (3) · Bestrophinopathy (2) · Central Serous Chorioretinopathy (2) · Choroideremia (2) · Abetalipoproteinemia (1) · Achromatopsia 3 (1) · Albinism (1) · Aniridia (1) · Bardet-Biedl Syndrome (1) · Blue cone monochromatism (1) · Charcot-Marie-Tooth Disease (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Genetic Diseases, Inborn (10) · Eye Diseases (9) · Eye Diseases, Hereditary (9) · Retinal Degeneration (9) · Macular Degeneration (7) · Retinal Diseases (6) · Retinal Dystrophies (6) · Uveal Diseases (5) · Cardiovascular Diseases (3) · Choroid Diseases (3) · Congenital Abnormalities (3) · Abnormalities, Multiple (2) · Ciliopathies (2) · Genetic Diseases, X-Linked (2)
Ranibizumab (1) · Sildenafil Citrate (1) · Visual Acuity (1)
Columbia University (2) · National Eye Institute (NEI) (2) · Barcelona Macula Foundation (1) · Foundation Fighting Blindness (1) · IRCCS San Raffaele (1) · Manhattan Eye, Ear & Throat Hospital (1) · Mayo Clinic (1) · Opus Genetics, Inc (1)
United States (8) · France (1) · Germany (1) · Spain (1)
Alan D. Marmorstein, Ph.D. (1) · Brian P Brooks, M.D. (1) · Donald Jackson Coleman, MD (1) · Fnu Ruchi, Ph.D. (1) · Lawrence A. Yannuzzi, MD (1) · Raymond Iezzi, M.D. (1) · Sophie J. Bakri, M.D. (1) · Stephen H Tsang, MD, PhD (1) · Todd Durham, PhD (1)
R24EY028758 (1), U01EY030547 (1)