5 completed, 3 withdrawn, 1 recruiting, 1 terminated. 4 Phase 2, 2 Not applicable, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Withdrawn 2 |
| Not applicable | 2 | Unknown 1, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow Angioid Streaks: new trials by email Literature Review of Angioid Streaks trials Research Report on Angioid Streaks
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Progression Assessment of PXE-associated Alterations Pseudoxanthoma Elasticum, Angioid Streaks | Recruiting | University Hospital, Bonn | 100 | 2024-09-01 | 2025-07-02 | |
| Antiangiogenic Therapy of CNV Associated With Angioid Streaks Intravitreal injection - Angioid Streaks of Macula | Not applicable | Unknown | The Filatov Institute of Eye Diseases and Tissue Therapy | 100 | 2018-03-27 | 2021-02-03 |
| Phase II Study Evaluating the Efficacy of Aflibercept for the Treatment of Choroidal Neovascularization in Angioid Streaks in Young Patients (ASTRID). Aflibercept - Choroidal Neovascularization in Angioid Streaks | Phase 2 | Withdrawn | Hospices Civils de Lyon | 2016-02-01 | 2017-01-06 | |
| Intravitreal Aflibercept for Therapy of Patients With Pseudoxanthoma Elasticum (PXE) Aflibercept - Pseudoxanthoma Elasticum | Phase 2 | Completed | University Hospital, Bonn | 15 | 2015-09-01 | 2019-05-07 |
| Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD Bevacizumab (Avastin; Genentech, Inc.), Bevacizumab, Dexamethasone, Verteporfin Photodynamic Therapy - Choroidal Neovascularization, Myopia | Not applicable | Withdrawn | Massachusetts Eye and Ear Infirmary | 2010-08-01 | 2014-01-14 | |
| Ranibizumab Therapy for Choroidal Neovascularization (CNV) Asociated With Angioid Streaks ranibizumab - Angioid Streaks | Phase 1 / Phase 2 | Withdrawn | University of Illinois at Chicago | 2009-12-01 | 2012-07-02 | |
| Ranibizumab to Treat Choroidal Neovascularization (CNV) in Patients With Pseudoxanthoma Elasticum (PXE) Intravitreal injection ranibizumab - Choroidal Neovascularization | Phase 2 | Completed | University Hospital, Bonn | 10 | 2007-08-01 | 2012-06-15 |
| Intravitreal Bevacizumab in Agioid Streaks intravitreal injection - Angioid Streaks, Choroidal Neovascularization | Phase 1 | Completed | University of Campania Luigi Vanvitelli | 5 | 2006-11-01 | 2016-02-08 |
| Use of Intravitreal Bevacizumab in Eyes With Choroidal Neovascularization Secondary to Angioid Streaks Intravitreal Bevacizumab - Angioid Streaks, Choroidal Neovascularization | Phase 3 | Terminated | Asociación para Evitar la Ceguera en México | 2005-11-01 | 2024-06-03 | |
| Effect of Intravitreal Bevacizumab on Non -Age-Related Macular Degeneration (AMD) Related Choroidal Neovascularization (CNV) bevacizumab - Choroidal Neovascularization | Phase 3 | Completed | Shahid Beheshti University of Medical Sciences | 31 | 2005-11-01 | 2008-07-11 |
| Evolution of Visual Impairment During Pseudoxanthoma Elasticum Pseudoxanthoma Elasticum | Completed | European Georges Pompidou Hospital | 38 | 2000-01-01 | 2007-11-07 |
Choroidal Neovascularization (8) · Pseudoxanthoma Elasticum (4) · Central Serous Chorioretinopathy (1) · Eye Diseases, Hereditary (1) · Multifocal Choroiditis (1) · Myopia (1) · White Dot Syndromes (1) · Wounds and Injuries (1)
Eye Diseases (11) · Retinal Diseases (11) · Choroid Diseases (8) · Metaplasia (8) · Neovascularization, Pathologic (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Uveal Diseases (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Genetic Diseases, Inborn (5) · Cardiovascular Diseases (4) · Congenital Abnormalities (4) · Connective Tissue Diseases (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4)
Bevacizumab (2) · Intravitreal Injections (2) · Ranibizumab (2) · aflibercept (2) · Dexamethasone (1) · Refractometry (1)
University Hospital, Bonn (3) · Asociación para Evitar la Ceguera en México (1) · European Georges Pompidou Hospital (1) · Hospices Civils de Lyon (1) · Massachusetts Eye and Ear Infirmary (1) · Shahid Beheshti University of Medical Sciences (1) · The Filatov Institute of Eye Diseases and Tissue Therapy (1) · University of Campania Luigi Vanvitelli (1) · University of Illinois at Chicago (1)
Germany (3) · France (1) · Iran (1) · Italy (1) · Mexico (1) · Ukraine (1)
Andrii MD Korol, PhD (1) · Frank G. Holz, MD (1) · Frank G. Holz, MD, DPhil (1) · Griselda Alvarez-Rivera, MD (1) · Hamid Ahmadieh, MD (1) · Hendrik PN Scholl, MD, MA (1) · Hugo Quiroz-Mercado, MD (1) · Ivana K Kim, MD (1) · Jans Fromow-Guerra, MD PhD (1) · Jennifer I Lim, MD (1) · Michele Rinaldi, MD (1)
2014 (1)