15 completed, 2 terminated, 1 unknown, 1 withdrawn. 19 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 15, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Precancerous Condition: new trials by email Literature Review of Precancerous Condition trials Research Report on Precancerous Condition
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer cetuximab, cisplatin, IMRT - Head and Neck Cancer, Precancerous Condition | Phase 3 | Completed | Radiation Therapy Oncology Group | 987 | 2011-06-01 | 2026-07-20 |
| Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia clinical observation, infrared photocoagulation therapy - Anal Cancer, Neoplasm of Uncertain Malignant Potential | Phase 3 | Completed | AIDS Malignancy Consortium | 120 | 2011-04-01 | 2020-08-04 |
| Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery rosuvastatin, placebo - Colorectal Cancer, Precancerous Condition | Phase 3 | Terminated | NSABP Foundation Inc | 406 | 2010-03-01 | 2023-08-16 |
| American Ginseng in Treating Patients With Fatigue Caused by Cancer American ginseng, placebo - Chronic Myeloproliferative Disorders, Fatigue | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 364 | 2008-10-01 | 2017-02-09 |
| S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000 Vitamin E, Selenium, Vitamin E placebo - Colorectal Cancer, Precancerous Condition | Phase 3 | Completed | SWOG Cancer Research Network | 8094 | 2008-06-01 | 2019-12-16 |
| Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer darbepoetin alfa, ferrous sulfate, sodium ferric gluconate complex in sucrose - Anemia, Leukemia | Phase 3 | Completed | Mayo Clinic | 502 | 2006-01-01 | 2011-05-17 |
| Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain educational intervention, Titrated pain management, questionnaire administration - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Phase 3 | Completed | Vanderbilt-Ingram Cancer Center | 98 | 2005-05-01 | 2012-09-06 |
| A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia Esomeprazole, Aspirin - Esophageal Cancer, Precancerous Condition | Phase 3 | Completed | University of Oxford | 2557 | 2005-03-10 | 2025-05-01 |
| Selenium for Prevention of Adenomatous Colorectal Polyps Selenium - Colorectal Cancer, Adenomatous Colorectal Polyps | Phase 3 | Terminated | University of Arizona | 1621 | 2005-01-20 | 2019-09-24 |
| Diindolylmethane in Treating Patients With Abnormal Cervical Cells oral microencapsulated diindolylmethane, polymerase chain reaction, cervical Papanicolaou test - Cervical Cancer, Precancerous Condition | Phase 3 | Completed | Barts and the London School of Medicine and Dentistry | 3000 | 2004-10-01 | 2013-08-07 |
| Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine, hepatitis A inactivated virus vaccine - Cervical Cancer, Precancerous Condition | Phase 3 | Completed | GlaxoSmithKline | 7466 | 2004-06-30 | 2019-03-08 |
| Epoetin Alfa in Treating Anemia in Patients With Solid Tumors epoetin alfa - Anemia, Leukemia | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 365 | 2003-06-01 | 2016-07-18 |
| Celecoxib in Preventing Skin Cancer in Patients With Actinic Keratoses celecoxib, Placebo - Precancerous Condition | Phase 2 / Phase 3 | Withdrawn | University of Alabama at Birmingham | 2001-12-01 | 2013-08-05 | |
| Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment ondansetron, placebo - Chronic Myeloproliferative Disorders, Leukemia | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 100 | 2000-10-01 | 2016-07-06 |
| St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer St. John's wort - Chronic Myeloproliferative Disorders, Fatigue | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 1999-12-01 | 2013-01-18 | |
| Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy epoetin alfa, placebo - Anemia, Breast Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 344 | 1998-12-01 | 2016-07-13 |
| Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps placebo, eflornithine, sulindac - Precancerous Condition | Phase 3 | Completed | National Cancer Institute (NCI) | 375 | 1998-07-01 | 2015-01-22 |
| T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum liposomal T4N5 lotion - Precancerous Condition | Phase 3 | Unknown | Applied Genetics | 30 | 1996-07-01 | 2013-11-06 |
| Fenretinide in Treating Patients With Cervical Neoplasia Fenretinide, Placebo - Cervical Cancer, Precancerous Condition | Phase 3 | Completed | M.D. Anderson Cancer Center | 39 | 1993-03-05 | 2018-10-24 |
Precancerous Conditions (19) · Leukemia (7) · Lymphoma (7) · Multiple Myeloma (7) · Neoplasms, Plasma Cell (7) · Burkitt Lymphoma (5) · Hodgkin Disease (5) · Immunoblastic Lymphadenopathy (5) · Immunoglobulin Light-chain Amyloidosis (5) · Leukemia, Hairy Cell (5) · Leukemia, Lymphocytic, Chronic, B-Cell (5) · Lymphoma, B-Cell, Marginal Zone (5) · Lymphoma, Follicular (5) · Lymphoma, Large B-Cell, Diffuse (5) · Lymphoma, Large-Cell, Anaplastic (5)
Neoplasms (19) · Neoplasms by Site (14) · Neoplasms by Histologic Type (11) · Immune System Diseases (8) · Blood Protein Disorders (7) · Cardiovascular Diseases (7) · DNA Virus Infections (7) · Disease Attributes (7) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Hemorrhagic Disorders (7) · Hemostatic Disorders (7) · Immunoproliferative Disorders (7) · Infections (7) · Lymphatic Diseases (7)
Epoetin Alfa (2) · Selenium (2) · Asian ginseng (1) · Aspirin (1) · Celecoxib (1) · Cetuximab (1) · Cisplatin (1) · Darbepoetin alfa (1) · Deoxyribonuclease (Pyrimidine Dimer) (1) · Early Intervention, Educational (1) · Eflornithine (1) · Esomeprazole (1) · Fenretinide (1) · Hypericum extract LI 160 (1) · Light Coagulation (1)
Alliance for Clinical Trials in Oncology (4) · AIDS Malignancy Consortium (1) · Applied Genetics (1) · Barts and the London School of Medicine and Dentistry (1) · GlaxoSmithKline (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · NSABP Foundation Inc (1) · National Cancer Institute (NCI) (1) · Radiation Therapy Oncology Group (1) · SWOG Cancer Research Network (1) · University of Alabama at Birmingham (1) · University of Arizona (1) · University of Oxford (1)
United States (16) · Canada (3) · United Kingdom (2) · Costa Rica (1) · Germany (1)
M. Peter Lance, MD (2) · Andy M. Trotti, MD (1) · Charles L. Loprinzi, MD (1) · Craig A. Elmets, MD (1) · Daniel B. Yarosh, PhD (1) · David J. Straus, MD (1) · David P. Steensma, MD (1) · Debra Barton, RN, PhD, AOCN, FAAN (1) · Frank Meyskens (1) · Janusz Jankowski, MD (1) · Maura Gillison, MD, PhD (1) · Michele Follen, MD, PhD (1) · Nancy Wells, DNSc, RN (1) · Norman Wolmark, MD (1)
PMID 16505427, PMID 17699008, PMID 18378608, PMID 18948732, PMID 20197322, PMID 20538001, PMID 21115882, PMID 21865087, PMID 22850119, PMID 23060037, PMID 23834901, PMID 23873171, PMID 24014882, PMID 24958910, PMID 25018097, PMID 25057165, PMID 25139208, PMID 25796338, PMID 26071347, PMID 26346155, PMID 26467666, PMID 26892991, PMID 27519183, PMID 29718393, PMID 30060087, PMID 30449625, PMID 30899530, PMID 31299087, PMID 32214382, PMID 35017496, PMID 35709811, PMID 35815403, PMID 35842229, PMID 36401615, PMID 36999619, PMID 37040086, PMID 39961279, PMID 40796225, PMID 41343184, PMID 42658511
2004 (1), P01CA041108 (1), P30CA015083 (1), P30CA016672 (1), P30CA023074 (1), P30CA068485 (1), R01CA088078 (1), U01CA121947 (1), U10CA037429 (1)