4 completed. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 1 | Completed 1 |
Follow Pineoblastoma: new trials by email Literature Review of Pineoblastoma trials Research Report on Pineoblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma Temozolomide, Irinotecan, Dasatinib - Pineoblastoma | Phase 2 | Completed | University of Regensburg | 4 | 2016-04-01 | 2021-08-05 |
| Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors Adavosertib, Irinotecan Hydrochloride - Central Nervous System Embryonal Tumor With Rhabdoid Features, Central Nervous System Embryonal Tumor, Not Otherwise Specified | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 76 | 2014-03-28 | 2023-09-26 |
| Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Bevacizumab, Irinotecan Hydrochloride, Temozolomide - Central Nervous System Neoplasm, Pineoblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 108 | 2010-11-22 | 2021-07-23 |
| Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors Stem Cell Transplant - Glioblastoma, Astrocytoma | Phase 2 | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 24 | 1998-03-01 | 2020-08-05 |
Pinealoma (4) · Central Nervous System Neoplasms (3) · Medulloblastoma (3) · Neuroectodermal Tumors, Primitive (2) · Astrocytoma (1) · Brain Neoplasms (1) · Glioblastoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Neuroblastoma (1) · Neuroectodermal Tumors, Primitive, Peripheral (1) · Rhabdoid Tumor (1) · Rhabdomyosarcoma (1) · Supratentorial Neoplasms (1)
Brain Diseases (4) · Central Nervous System Diseases (4) · Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Neuroectodermal Tumors (4) · Brain Neoplasms (3) · Glioma (3) · Neoplasms, Germ Cell and Embryonal (3) · Central Nervous System Neoplasms (1)
Irinotecan (3) · Temozolomide (2) · Bevacizumab (1) · Dasatinib (1) · Disulfides (1) · Immunoglobulin G (1) · Sirolimus (1) · Stem Cell Transplantation (1) · adavosertib (1)
National Cancer Institute (NCI) (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · University of Regensburg (1)
United States (3) · Canada (2) · Australia (1) · Germany (1) · New Zealand (1) · Puerto Rico (1)
Adam S Levy (1) · Kristina A Cole (1) · Stewart Goldman, MD (1)
U10CA098543 (1), U10CA180886 (1), UM1CA097452 (1)