5 completed, 5 recruiting, 2 suspended, 2 unknown. 9 Phase 2, 3 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 3, Suspended 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 1 | 3 | Recruiting 2, Terminated 1 |
| Not applicable | 2 | Completed 1, Recruiting 1 |
Follow Peritoneal Mesothelioma: new trials by email Literature Review of Peritoneal Mesothelioma trials Research Report on Peritoneal Mesothelioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First-line Treatment With Dual Immunotherapy Combined With Anti-angiogenesis for Unresectable Advanced Malignant Peritoneal Mesothelioma Sintilimab, Ipilimumab N01, Bevacizumab - Peritoneal Mesothelioma, First-line Therapy | Phase 2 | Not yet recruiting | Fudan University | 19 | 2026-10-30 | 2026-10-23 |
| A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors IDE892, IDE397 - NSCLC Adenocarcinoma, Gastroesophageal Cancer (GC) | Phase 1 | Recruiting | IDEAYA Biosciences | 260 | 2026-03-04 | 2026-09-28 |
| PTC-Guided Therapy for Peritoneal Mesothelioma PTC guided individualized treatment, Standard chemotherapy regimens - Peritoneal Mesothelioma | Not applicable | Recruiting | Beijing Tsinghua Chang Gung Hospital | 347 | 2025-12-02 | 2026-06-15 |
| IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE Cancers DOMVANALIMAB + ZIMBERELIMAB, DOMVANALIMAB + ZIMBERELIMAB + FOLFOX-4 - Peritoneal Mesothelioma, Gestational Trophoblastic Tumor | Phase 2 | Active not recruiting | Hospices Civils de Lyon | 27 | 2025-10-01 | 2026-06-25 |
| A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma Pemetrexed, Cisplatin, Carboplatin - Malignant Peritoneal Mesothelioma, Peritoneal Mesothelioma | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 64 | 2023-09-21 | 2026-09-24 |
| A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers XmAb20717 - Microsatellite High Cancers, Peritoneal Mesothelioma | Phase 2 | Suspended | M.D. Anderson Cancer Center | 140 | 2022-08-05 | 2026-10-13 |
| A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma Nivolumab, Ipilimumab - Mesothelioma, Peritoneal Mesothelioma | Phase 2 | Completed | University of Chicago | 2 | 2021-12-01 | 2024-01-03 |
| Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies Sodium Thiosulfate, 5-Fluorouracil, Oxaliplatin - Peritoneal Mesothelioma, Peritoneal Carcinomatosis | Phase 1 | Recruiting | National Cancer Institute (NCI) | 60 | 2021-10-19 | 2026-10-16 |
| Treatment of Malignant Peritoneal Mesothelioma (MESOTIP) PIPAC, Cisplatin, Pemetrexed - Peritoneal Mesothelioma, Peritoneal Carcinomatosis | Phase 2 | Suspended | Institut du Cancer de Montpellier - Val d'Aurelle | 66 | 2020-09-10 | 2026-02-09 |
| Magnetic Resonance Imaging for Detection of Peritoneal Mesothelioma HR-MRI, Standard CT Imaging, Ultrasound - Mesothelioma, Peritoneal Mesothelioma | Not applicable | Completed | University of Chicago | 26 | 2018-10-10 | 2024-07-31 |
| Intraperitoneal MCY-M11 (Mesothelin-targeting CAR) for Treatment of Advanced Ovarian Cancer and Peritoneal Mesothelioma MCY-M11, Cyclophosphamide - Peritoneal Mesothelioma, Fallopian Tube Adenocarcinoma | Phase 1 | Terminated | MaxCyte, Inc. | 14 | 2018-08-27 | 2021-09-05 |
| A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1) tremelimumab plus MEDI4736 - Pleural Mesothelioma, Peritoneal Mesothelioma | Phase 2 | Unknown | Italian Network for Tumor Biotherapy Foundation | 40 | 2015-10-01 | 2015-10-27 |
| Genomic Analysis of Peritoneal Mesothelioma by CGH Arrays comparative genomic analysis - Peritoneal Mesothelioma | Completed | Hospices Civils de Lyon | 33 | 2013-05-01 | 2016-07-26 | |
| Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed Peritoneal Carcinomatosis, Pseudomyxoma Peritonei | Recruiting | Universitaire Ziekenhuizen KU Leuven | 125 | 2012-05-01 | 2026-09-03 | |
| HIPEC for Peritoneal Carcinomatosis HIPEC, Mitomycin C - Peritoneal Carcinomatosis, Colorectal Cancer | Phase 2 | Completed | Albert Einstein College of Medicine | 51 | 2011-11-01 | 2024-10-24 |
| French National Registry of Rare Peritoneal Surface Malignancies Non interventional - Rare Peritoneal Surface Malignancies, Pseudomyxoma Peritonei | Unknown | Hospices Civils de Lyon | 2171 | 2010-10-01 | 2017-08-22 | |
| Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapy IMC-A12 - Pleural Mesothelioma, Peritoneal Mesothelioma | Phase 2 | Completed | National Cancer Institute (NCI) | 20 | 2010-06-02 | 2018-04-10 |
Mesothelioma (5) · Mesothelioma, Malignant (5) · Peritoneal Neoplasms (4) · Pseudomyxoma Peritonei (3) · Appendiceal Neoplasms (2) · Colorectal Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Carcinoid Tumor (1) · Carcinoma, Neuroendocrine (1) · Carcinoma, Transitional Cell (1) · Cystadenocarcinoma, Serous (1) · Desmoplastic Small Round Cell Tumor (1) · Esophageal Squamous Cell Carcinoma (1) · Fever (1) · Gastro-enteropancreatic neuroendocrine tumor (1)
Neoplasms (14) · Neoplasms by Histologic Type (12) · Neoplasms, Glandular and Epithelial (12) · Neoplasms by Site (11) · Adenoma (8) · Neoplasms, Mesothelial (8) · Thoracic Neoplasms (7) · Carcinoma (6) · Lung Diseases (6) · Respiratory Tract Diseases (6) · Respiratory Tract Neoplasms (6) · Adenocarcinoma (5) · Digestive System Diseases (5) · Digestive System Neoplasms (5) · Lung Neoplasms (5)
Cisplatin (3) · Doxorubicin (2) · Mitomycin (2) · Pemetrexed (2) · Bevacizumab (1) · Carboplatin (1) · Comparative Genomic Hybridization (1) · Cyclophosphamide (1) · Fluorouracil (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Ipilimumab (1) · Nivolumab (1) · Oxaliplatin (1) · Ultrasonography (1) · cixutumumab (1)
Hospices Civils de Lyon (3) · National Cancer Institute (NCI) (2) · University of Chicago (2) · Albert Einstein College of Medicine (1) · Beijing Tsinghua Chang Gung Hospital (1) · Fudan University (1) · IDEAYA Biosciences (1) · Institut du Cancer de Montpellier - Val d'Aurelle (1) · Italian Network for Tumor Biotherapy Foundation (1) · M.D. Anderson Cancer Center (1) · MaxCyte, Inc. (1) · Memorial Sloan Kettering Cancer Center (1) · Universitaire Ziekenhuizen KU Leuven (1)
United States (9) · France (3) · China (2) · Belgium (1) · Italy (1)
Andrew M Blakely, M.D. (1) · Arvind Nageshwara Dasaru, MD (1) · Claudio Dansky Ullmann, MD (1) · Edward Chan, MD (1) · Garrett Nash, MD (1) · Hedy Kindler, MD (1) · John McAuliffe, M.D. (1) · Kiran Turaga, MD (1) · Luana Calabro', MD, PhD (1) · Raffit Hassan, M.D. (1)