15 completed, 4 unknown, 2 terminated, 2 withdrawn. 3 Not applicable, 3 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Comparative Genomic Hybridization: new trials by email Literature Review of Comparative Genomic Hybridization trials Research Report on Comparative Genomic Hybridization
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Validation of a Clinical Screening Grid for Syndromic Schizophrenia Array comparative genomic hybridization - Schizophrenia | Not applicable | Terminated | Hôpital le Vinatier | 129 | 2016-07-01 | 2025-03-06 |
| Genomic Analysis of Peritoneal Mesothelioma by CGH Arrays comparative genomic analysis - Peritoneal Mesothelioma | Completed | Hospices Civils de Lyon | 33 | 2013-05-01 | 2016-07-26 | |
| Biomarkers in Tissue Samples From Patients With Ewing Sarcoma DNA analysis, comparative genomic hybridization, gene expression analysis - Sarcoma | Completed | Children's Oncology Group | 166 | 2011-12-01 | 2015-05-12 | |
| Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma prednisone, cyclophosphamide, etoposide - Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma | Phase 2 | Completed | University of Nebraska | 34 | 2011-07-06 | 2023-09-22 |
| A Study of Therapy Selected by Molecular/Metabolic Profiling in Patients With Previously Treated Metastatic Pancreatic Cancer Drug will be recommended based on IHC/Fish, CGH and Pan-XenoBank - Previously Treated Metastatic Pancreatic Cancer | Phase 2 | Completed | Translational Drug Development | 35 | 2010-09-01 | 2012-07-17 |
| Biomarkers in Young Patients With Neuroblastoma DNA analysis, DNA methylation analysis, RNA analysis - Neuroblastoma | Completed | Children's Oncology Group | 380 | 2010-07-01 | 2016-05-18 | |
| Study of Blood and Tissue Samples From Patients Receiving Androgen Deprivation for Newly Diagnosed Prostate Cancer antiandrogen therapy, releasing hormone agonist therapy, DNA analysis - Prostate Cancer | Not applicable | Unknown | Cancer Research UK | 120 | 2008-09-01 | 2014-01-10 |
| Sunitinib Before and After Surgery in Treating Patients With Stage IV Kidney Cancer motexafin gadolinium, sunitinib malate, comparative genomic hybridization - Kidney Cancer | Phase 2 | Unknown | Abramson Cancer Center at Penn Medicine | 20 | 2008-06-01 | 2014-01-10 |
| Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer comparative genomic hybridization, molecular genetic technique, mutation analysis - Liver Cancer | Withdrawn | Vanderbilt-Ingram Cancer Center | 2007-07-01 | 2013-04-10 | ||
| Oral HPV Infection in Young Men comparative genomic hybridization, gene expression analysis, study of socioeconomic and demographic variables - Head and Neck Cancer, Infection | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 500 | 2007-05-01 | 2019-01-17 | |
| Studying Genes in Blood and Lung Fluid Samples From Patients With Chronic Obstructive Pulmonary Disease With or Without a Previous Diagnosis of Lung Cancer or With Asthma Treated With Budesonide and Formoterol budesonide/formoterol fumarate dihydrate inhalation aerosol, DNA methylation analysis, comparative genomic hybridization - Lung Cancer, Precancerous Condition | Phase 1 | Completed | British Columbia Cancer Agency | 30 | 2007-01-01 | 2012-03-09 |
| Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy temozolomide, comparative genomic hybridization, polymorphism analysis - Brain and Central Nervous System Tumors, Thrombocytopenia | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 10 | 2006-11-11 | 2018-07-09 | |
| S8814A Biomarkers in Predicting Outcome in Postmenopausal Women With Hormone Receptor-Positive, Node-Positive Breast Cancer Treated With Tamoxifen With or Without Cyclophosphamide, Doxorubicin, and Fluorouracil comparative genomic hybridization, microarray analysis, reverse transcriptase-polymerase chain reaction - Breast Cancer | Completed | SWOG Cancer Research Network | 750 | 2006-07-01 | 2013-05-30 | |
| DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia DNA methylation analysis, comparative genomic hybridization, fluorescence in situ hybridization - Leukemia | Completed | ECOG-ACRIN Cancer Research Group | 418 | 2006-03-23 | 2020-07-31 | |
| Lapatinib and Vinorelbine in Treating Patients With Advanced Solid Tumors lapatinib ditosylate, vinorelbine ditartrate, comparative genomic hybridization - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, Davis | 22 | 2005-12-01 | 2012-04-19 |
| Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer cyclophosphamide, epirubicin hydrochloride, gemcitabine hydrochloride - Breast Cancer | Phase 3 | Unknown | Cambridge University Hospitals NHS Foundation Trust | 800 | 2005-01-01 | 2013-08-07 |
| Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer comparative genomic hybridization, gene expression microarray analysis, proteomic profiling analysis - Lung Cancer | Recruiting | Vanderbilt-Ingram Cancer Center | 4000 | 2003-12-01 | 2026-04-27 | |
| Research Study in Patients With Advanced Ovarian Epithelial Cancer Comparative Genomic Hybridization, Laboratory Biomarker Analysis, Polymerase Chain Reaction - Ovarian Serous Cystadenocarcinoma, Ovarian Serous Surface Papillary Adenocarcinoma | Withdrawn | Gynecologic Oncology Group | 2002-11-01 | 2015-06-01 | ||
| Diagnostic Study to Predict the Risk of Developing Metastatic Cancer in Patients With Stage I or Stage II Melanoma comparative genomic hybridization, cytogenetic analysis, fluorescence in situ hybridization - Melanoma (Skin) | Not applicable | Completed | Alliance for Clinical Trials in Oncology | 314 | 2002-09-01 | 2016-07-01 |
| Studying Genes for Barrett's Esophagus in Brothers and Sisters comparative genomic hybridization, genetic linkage analysis, laboratory biomarker analysis - Esophageal Cancer, Precancerous Condition | Unknown | Medical Research Council | 400 | 2002-06-01 | 2013-08-12 |
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Lung Neoplasms (3) · Precancerous Conditions (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Central Nervous System Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Astrocytoma (1) · Barrett Esophagus (1) · Basal Cell Nevus Syndrome (1) · Brain Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Congenital Abnormalities (1)
Children's Oncology Group (3) · Alliance for Clinical Trials in Oncology (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · Vanderbilt-Ingram Cancer Center (2) · Abramson Cancer Center at Penn Medicine (1) · British Columbia Cancer Agency (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Cancer Research UK (1) · ECOG-ACRIN Cancer Research Group (1) · Gynecologic Oncology Group (1) · Hospices Civils de Lyon (1) · Hôpital le Vinatier (1) · Medical Research Council (1) · SWOG Cancer Research Network (1) · Translational Drug Development (1)
United States (12) · United Kingdom (3) · Canada (2) · Australia (1) · France (1)
Allen E. Bale, MD (1) · Ari M. Melnick, MD (1) · David Gershenson (1) · F. Stephen Hodi, MD (1) · Fabien Maldonado, MD (1) · Helen K. Chew, MD (1) · Helena Earl, MBBS, PhD, FRCP (1) · Jaclyn A. Biegel, PhD (1) · John M. Maris, MD (1) · Julie M Vose (1) · Kathy S. Albain, MD (1) · Keith T. Flaherty, MD (1) · Laura Goff, MD (1) · Maura Gillison, MD, PhD (1)
PMID 18809146, PMID 24360787, PMID 24386300, PMID 26715442, PMID 26882907
P30CA006973 (2), P30CA068485 (2), P30CA036727 (1), P30CA093373 (1), R01CA102353 (1), U10CA031946 (1), U10CA032102 (1), U10CA076001 (1)