12 recruiting, 8 completed, 6 not yet recruiting, 3 active not recruiting. 16 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Recruiting 10, Active not recruiting 3, Completed 2, Not yet recruiting 1 |
| Phase 4 | 2 | Not yet recruiting 2 |
| Phase 3 | 1 | Recruiting 1 |
Follow Pelvic Organ Prolapse (POP): new trials by email Literature Review of Pelvic Organ Prolapse (POP) trials Research Report on Pelvic Organ Prolapse (POP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen - Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI) | Phase 4 | Not yet recruiting | University of California, Los Angeles | 120 | 2026-11-01 | 2026-09-15 |
| Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management Suzetrigine, Placebo - Pelvic Organ Prolapse (POP), Postoperative Pain | Phase 4 | Not yet recruiting | Aditi Talkad | 48 | 2026-11-01 | 2026-10-02 |
| Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious) Surgical mesh for pelvic organ prolapse repair (ProGYNious) - Pelvic Organ Prolapse (POP), Synthetic Mesh | Not applicable | Recruiting | A.M.I. Agency for Medical Innovations GmbH | 100 | 2026-10-28 | 2026-10-30 |
| Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial Perineal protection device, BabySlide, Standard manual perineal support - Pelvic Floor Dysfunction, Perineal Laceration | Not applicable | Not yet recruiting | Region Skane | 4226 | 2026-10-05 | 2026-10-07 |
| Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration Poly-L-Lactic Acid (Sculptra) injection, Placebo injection (sterile water) - Pelvic Organ Prolapse (POP), Cystocele | Not applicable | Recruiting | Cassandra Kisby | 20 | 2026-08-20 | 2026-08-21 |
| Urinary Continence After Vaginal Surgery for Genital Prolapse in the Spanish Population. Vaginal surgery for pelvic organ prolapse - Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 1042 | 2026-08-01 | 2026-06-04 | |
| The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial) Manchester procedure, Vaginal hysterectomy - Uterine Prolapse, Pelvic Organ Prolapse Vaginal Surgery | Not applicable | Recruiting | Tampere University Hospital | 426 | 2026-05-01 | 2026-05-11 |
| Evaluation of a Personalizable Pessary for Pelvic Organ Prolapse Novel Personalizable Pessary - Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | University of Alberta | 43 | 2026-04-30 | 2026-06-04 |
| The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation Early individualized pelvic floor muscle training (PFMT) - Urinary Incontinence, Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | Vastra Gotaland Region | 380 | 2026-04-07 | 2026-05-27 |
| Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension Bupivacaine, Normal Saline - Pelvic Organ Prolapse (POP), Postoperative Pain | Not applicable | Recruiting | Erkan Gol | 58 | 2026-03-09 | 2026-03-11 |
| Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse Surgery Vaginal Estrogen - Twice Weekly, Vaginal Estrogen - Daily - Pelvic Organ Prolapse (POP) | Phase 3 | Recruiting | Sarah Wozney | 180 | 2026-01-01 | 2026-08-20 |
| Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious) Laparoscopic lateral suspension with surgical mesh (LatGYNious) - Pelvic Organ Prolapse (POP), Genital Prolapse | Not applicable | Recruiting | A.M.I. Agency for Medical Innovations GmbH | 85 | 2025-11-01 | 2026-07-28 |
| Are There Benefits of Using Energy-based Devices for Opportunistic Salpingo-oophorectomy During Vaginal Hysterectomy Compared to a Standard Cold Approach? LigaSure MaryLand, Standard salpingo-oophorectomy technique - Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | Wolfson Medical Center | 70 | 2025-10-16 | 2026-01-30 |
| Accelerometer Measured Early Recovery After Prolapse Surgery Postoperative Exercise regimen - Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | NICHD Pelvic Floor Disorders Network | 288 | 2025-10-02 | 2026-04-27 |
| POPQ Associated With Total Laparoscopic Hysterectomy Questionnaire and Physical Exam - Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle | Not yet recruiting | Medical University of Silesia | 2000 | 2025-10-01 | 2025-08-22 | |
| Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse - Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery | Not applicable | Recruiting | University of Sao Paulo General Hospital | 86 | 2025-09-15 | 2026-01-22 |
| Effectiveness of Laparoscopic Lateral Suspension With or Without Hysterectomy in Pelvic Organ Prolapse Pelvic Organ Prolapse (POP), Uterine Prolapse | Completed | Havva Betül Bacak | 87 | 2025-05-28 | 2025-08-06 | |
| Efficacy and Safety of Laparoscopic Lateral Suspension and Transvaginal Sacrospinous Ligament Fixation in Patients With Pelvic Organ Prolapse laparoscopic lateral suspension, Transvaginal sacrospinous ligament fixation - Pelvic Organ Prolapse (POP) | Not applicable | Active not recruiting | Peking University People's Hospital | 86 | 2025-04-05 | 2026-02-02 |
| Impact of Equestrian Sports, CrossFit, and Gym Training on Pelvic Floor Health (PELFISPORT ) Pelvic Floor Dysfunction, Urinary Incontinence | Not yet recruiting | University of Oviedo | 200 | 2025-02-28 | 2025-02-27 | |
| Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery Telephone follow-up - Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI) | Recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 382 | 2024-12-01 | 2026-05-22 |
Showing 20 of 29. Sign in to see all of them.
Pelvic Organ Prolapse (29) · Urinary Incontinence (5) · Urinary Incontinence, Stress (5) · Uterine Prolapse (5) · Pain, Postoperative (3) · Cystocele (2) · Pelvic Floor Disorders (2) · Prolapse (2) · Encopresis (1) · Endometrial Hyperplasia (1) · Leiomyoma (1) · Motor Activity (1) · Rectal Prolapse (1) · Rectocele (1) · Sexual Dysfunction, Physiological (1)
Pathological Conditions, Anatomical (29) · Pathological Conditions, Signs and Symptoms (29) · Prolapse (27) · Urogenital Diseases (17) · Female Urogenital Diseases (16) · Female Urogenital Diseases and Pregnancy Complications (16) · Male Urogenital Diseases (11) · Signs and Symptoms (11) · Urologic Diseases (10) · Lower Urinary Tract Symptoms (8) · Urination Disorders (8) · Urological Manifestations (8) · Genital Diseases (7) · Genital Diseases, Female (6) · Uterine Diseases (6)
Surgical Mesh (2) · Analgesics, Opioid (1) · Bupivacaine (1) · Control Groups (1) · Dehydroepiandrosterone (1) · Estriol (1) · Hysterectomy, Vaginal (1) · Ibuprofen (1) · Injections (1) · Oxycodone (1) · Restraint, Physical (1) · Saline Solution (1) · Sodium Chloride (1) · Surveys and Questionnaires (1) · Tramadol (1)
A.M.I. Agency for Medical Innovations GmbH (3) · NICHD Pelvic Floor Disorders Network (2) · Aditi Talkad (1) · Azerbaijan Medical University (1) · Bagcilar Training and Research Hospital (1) · Cassandra Kisby (1) · Coloplast A/S (1) · Erkan Gol (1) · Havva Betül Bacak (1) · Hillel Yaffe Medical Center (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Lund University (1) · Medical University of Silesia (1) · Peking University People's Hospital (1) · Poznan University of Medical Sciences (1)
United States (6) · Germany (3) · Sweden (3) · Turkey (Türkiye) (3) · Austria (2) · Canada (2) · China (2) · Israel (2) · Poland (2) · Azerbaijan (1) · Brazil (1) · Finland (1) · Latvia (1) · Spain (1)
A Lenore Ackeman, MD, PhD (1) · Amanda White, MD (1) · Balazs Stenczer, MD (1) · Barry Jarnagin, MD (1) · Cassandra Kisby, MD MS FACOG FACS (1) · Jonia Alsheik, Dr (1) · Lucas Vasas, MD (1) · Matthew Barber, MD (1) · Sabadell Jordi, MD, PhD. (1) · Sarah Wozney, MD, MScHQ (1) · Tina Cadenbach-Blome, Dr. med. (1)
PMID 22015881, PMID 22777367, PMID 22777368, PMID 24618964, PMID 27159758, PMID 28734829, PMID 31449806, PMID 31637890, PMID 32769645, PMID 33030871, PMID 35843545, PMID 37318279, PMID 37672283, PMID 38247214
K12AR084231 (1), U01HD041249 (1), U10HD041250 (1), U10HD041261 (1), U10HD041267 (1), U10HD054136 (1), U10HD054214 (1), U10HD054215 (1), U10HD054241 (1), U24HD069031 (1), UG1HD041267 (1), UG1HD054214 (1), UG1HD054241 (1), UG1HD069010 (1), UG1HD069013 (1)