4 completed, 2 terminated, 1 active not recruiting, 1 not yet recruiting. 6 Phase 2, 4 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 2, Terminated 2, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 4 | Completed 2, Terminated 2 |
| Phase 1 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
Follow Pediatric Growth Hormone Deficiency: new trials by email Literature Review of Pediatric Growth Hormone Deficiency trials Research Report on Pediatric Growth Hormone Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of GenSci134 in Children With Growth Hormone Deficiency (PGHD) GenSci134 Injection, Recombinant Human Growth Hormone Injection(Norditropin® FlexPro®) - Pediatric Growth Hormone Deficiency | Phase 1 / Phase 2 | Not yet recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 128 | 2026-03-06 | 2026-03-04 |
| A Study (Phase 1b/2) of GS3-007a Oral Treatment in Children With Growth Hormone Deficiency (PGHD) GS3-007a dry suspension, Placebo for GS3-007a dry suspension, rhGH injection - Pediatric Growth Hormone Deficiency | Phase 1 / Phase 2 | Recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 88 | 2026-01-18 | 2026-09-16 |
| Korean Post-marketing Surveillance Ngenla® Pre-filled Pen Injection for the Treatment of Pediatric Patients With Growth Disturbance Due to Insufficient Secretion of Growth Hormone Ngenla - Pediatric Growth Hormone Deficiency | Active not recruiting | Pfizer | 565 | 2024-06-20 | 2026-01-27 | |
| A Study to Compare the Experiences of Taking Daily Growth Hormone Injections to Weekly Ngenla in Children With Low Levels of Growth Hormone Sharps bin to collect used needles/injections - Pediatric Growth Hormone Deficiency | Withdrawn | Pfizer | 2024-01-01 | 2024-02-09 | ||
| A Study to Evaluating the Efficacy and Safety of Recombinant Long-acting Human Growth Hormone (TJ101) in Children With Growth Hormone Deficiency TJ101, NordiFlex - Pediatric Growth Hormone Deficiency | Phase 3 | Completed | TJ Biopharma Co., Ltd. | 168 | 2021-01-25 | 2024-04-15 |
| Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children MOD-4023, Somatropin - Pediatric Growth Hormone Deficiency | Phase 3 | Completed | OPKO Health, Inc. | 224 | 2016-12-01 | 2025-07-20 |
| Versartis Trial in Pre-pubertal Japanese Children With Growth Hormone Deficiency (GHD) to Assess Long-Acting Growth Hormone (Somavaratan, VRS-317) Somavaratan (VRS-317) - Pediatric Growth Hormone Deficiency, Growth Disorders | Phase 2 / Phase 3 | Terminated | Versartis Inc. | 41 | 2015-08-08 | 2022-07-25 |
| Versartis Long-Term Safety Study of Somavaratan somavaratan - Pediatric Growth Hormone Deficiency | Phase 2 / Phase 3 | Terminated | Versartis Inc. | 385 | 2014-03-03 | 2018-03-09 |
| Versartis Trial in Children to Assess Long-Acting Growth Hormone Experimental: VRS-317 - Pediatric Growth Hormone Deficiency | Phase 1 / Phase 2 | Completed | Versartis Inc. | 64 | 2012-10-01 | 2022-07-26 |
| Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children MOD-4023, Somatropin - Pediatric Growth Hormone Deficiency | Phase 2 | Completed | OPKO Health, Inc. | 56 | 2012-02-01 | 2020-01-23 |
Dwarfism, Pituitary (3) · Growth Disorders (2) · Dwarfism (1)
Bone Diseases (3) · Bone Diseases, Developmental (3) · Bone Diseases, Endocrine (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Endocrine System Diseases (3) · Hypopituitarism (3) · Hypothalamic Diseases (3) · Musculoskeletal Diseases (3) · Nervous System Diseases (3) · Pituitary Diseases (3) · Dwarfism (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Human Growth Hormone (3) · MOD-4023 (2) · Injections (1) · somatrogon (1)
Versartis Inc. (3) · Changchun GeneScience Pharmaceutical Co., Ltd. (2) · OPKO Health, Inc. (2) · Pfizer (2) · TJ Biopharma Co., Ltd. (1)
China (3) · Greece (2) · South Korea (2) · United States (2) · Argentina (1) · Australia (1) · Belarus (1) · Bulgaria (1) · Canada (1) · Colombia (1) · Georgia (1) · Hungary (1) · India (1) · Israel (1) · Japan (1)
Will Charlton, MD (2) · Tony Cruz (1) · Zvi Zadik, MD (1)
PMID 28323965, PMID 35405011, PMID 37955005, PMID 38053515, PMID 38717038, PMID 42372104