11 not yet recruiting, 5 completed, 5 recruiting, 1 active not recruiting. 17 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Not yet recruiting 8, Recruiting 5, Completed 4 |
| Phase 2 | 1 | Completed 1 |
Follow Paroxysmal Atrial Fibrillation (PAF): new trials by email Literature Review of Paroxysmal Atrial Fibrillation (PAF) trials Research Report on Paroxysmal Atrial Fibrillation (PAF)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Home Monitor for AA Burden Detection IIT in TWN Paroxysmal Atrial Fibrillation (PAF), Atrial Flutter | Not yet recruiting | National Taiwan University Hospital | 30 | 2026-12-01 | 2026-10-07 | |
| A Global Randomized Trial Evaluating the FARAFLEX™ Mapping and Pulsed Field Ablation System With Electrographic Flow Mapping in Patients Undergoing Repeat Ablation for Atrial Fibrillation FARAFLEX Mapping and Pulsed Field Ablation System - Atrial Fibrillation (AF), Persistent Atrial Fibrillation (PersAF) | Not applicable | Not yet recruiting | Boston Scientific Corporation | 650 | 2026-11-01 | 2026-09-28 |
| Cryoballoon Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Paroxysmal Atrial Fibrillation (PAF) | Not yet recruiting | Shenyang Northern Hospital | 50 | 2026-10-15 | 2026-10-07 | |
| Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial Fibrillation PulseSelect Pulse Field Ablation (PFA) System - Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation | Not applicable | Not yet recruiting | Medtronic Cardiac Ablation Solutions | 320 | 2026-10-01 | 2026-10-09 |
| Sphere-9 PAF China Study Catheter ablation using Sphere-9™ Catheter and Affera™ Integrated Mapping and Ablation System - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | Medtronic Cardiac Ablation Solutions | 180 | 2026-09-02 | 2026-08-27 |
| A Comparative Study of Percutaneous Pulsed Field Ablation Guided by Ultrasound Alone Versus Fluoroscopy in Patients With Atrial Fibrillation Percutaneous pulsed field ablation is performed under ultrasound-only guidance in patients with paroxysmal atrial fibrillation., Patients with paroxysmal atrial fibrillation underwent percutaneous pulsed field ablation under fluoroscopic guidance. - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | China National Center for Cardiovascular Diseases | 276 | 2026-08-15 | 2026-08-13 |
| Intracardiac Echocardiography-guided Versus Electroanatomical Mapping-guided Pulsed Field Ablation for Paroxysmal Atrial Fibrillation In the ICE group, positioning/contact of the ablation catheter will be performed under ICE guidance. In the mapping group, guidance will be performed using three-dimensional electroanatomical mapping. - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Recruiting | Mitera Hospital | 292 | 2026-08-01 | 2026-08-19 |
| Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation FARAFLEX Mapping and Pulsed Field Ablation (PFA) System - Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation | Not applicable | Recruiting | Boston Scientific Corporation | 571 | 2026-07-07 | 2026-09-24 |
| Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF) Sphere-9 Catheter Ablation - Atrial Fibrillation (AF), Persistent Atrial Fibrillation | Not applicable | Recruiting | Medtronic Cardiac Ablation Solutions | 400 | 2026-04-08 | 2026-10-19 |
| Grid eXplore Mapping Study Grid X and EnSite X v3.1.1 Software - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Recruiting | Abbott Medical Devices | 200 | 2026-04-02 | 2026-07-01 |
| Pulsed Field Ablation of SVC and PV in Paroxysmal Atrial Fibrillation (PASPA Study) PFA - PV + SVCI, PFA - PVI only - Paroxysmal Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | Changhai Hospital | 650 | 2025-11-01 | 2025-09-25 |
| A Clinical Study on the Use of a Domestically Produced Three-dimensional Cardiac Electrophysiological Mapping System Combined With Pressure Monitoring Technology and Star Mapping Technology for the Treatment of Paroxysmal Atrial Fibrillation. FireMagic™ Magbot Ablation Catheter 、FireMagic™ TrueForce™ Ablation Catheter - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | Shanghai MicroPort EP MedTech Co., Ltd. | 20 | 2025-09-30 | 2025-06-27 |
| A Clinical Study on the Use of a Domestically Produced Cryoablation System Combined With Balloon Cryoablation Technology for the Treatment of Paroxysmal Atrial Fibrillation IceMagic™ CryoAblation Catheter - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | Shanghai MicroPort EP MedTech Co., Ltd. | 20 | 2025-08-31 | 2025-06-27 |
| Clinical Study on the Efficiency of Rapid Arrhythmia Mapping Using EasyStars™ High Density Mapping Catheter Applications EasyStars™ High Density Mapping Catheter - Ventricular Tachycardia (VT), Atrial Tachycardia | Not applicable | Not yet recruiting | Shanghai MicroPort EP MedTech Co., Ltd. | 300 | 2025-08-30 | 2025-07-31 |
| A Prospective Clinical Study to Evaluate the Safety and Effectiveness of Pulmonary Vein Isolation Plus Box Isolation of Fibrotic Areas With the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation Globe Pulsed Field System - Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation | Not applicable | Recruiting | Kardium Inc. | 115 | 2025-06-10 | 2025-06-16 |
| Multi-Centre Based Study Recognition of Atrial Fibrillation With the Corsano CardioWatch 287-2 System Corsano CardioWatch 287-2 - Atrial Fibrillation (AF), Paroxysmal Atrial Fibrillation (PAF) | Not yet recruiting | Corsano Health B.V. | 350 | 2025-05-01 | 2025-05-02 | |
| Real-world Safety and Effectiveness Registry of Catheter Ablation of Paroxysmal Atrial Fibrillation as Initial Control Therapy With the Thermocool SmartTouch SF Catheter (A Sub-study of REAL AF Registry) Ablation - Paroxysmal Atrial Fibrillation (PAF) | Active not recruiting | Heart Rhythm Clinical and Research Solutions, LLC | 344 | 2024-04-01 | 2025-10-31 | |
| Pulsed ElectRic FiEld Versus Cryoballoon for PAF Single-Shot Pulsed Field Ablation (FARAPULSE™ Pulsed Field Ablation System), Single-Shot Cryoballoon Devices (Arctic Front Advance PRO, Medtronic Inc., Minneapolis, MN, USA; POLARx and POLARx FIT Balloon Catheter, Marlborough, MA, USA) - Atril Fibrillation, Cardiac Arrhythmia | Not applicable | Completed | Universitair Ziekenhuis Brussel | 269 | 2023-09-27 | 2025-08-03 |
| First in Man Study of Pulsed Field Ablation System for the Treatment of Paroxysmal Atrial Fibrillation in 1 Patient CardioPulsesTM pulsed field ablation system - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Completed | Hangzhou Dinova EP Technology Co., Ltd | 10 | 2020-12-18 | 2026-03-05 |
| INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT) Flecainide Acetate - Paroxysmal Atrial Fibrillation (PAF) | Phase 2 | Completed | InCarda Therapeutics, Inc. | 176 | 2018-05-29 | 2024-05-14 |
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Atrial Fibrillation (22) · Arrhythmias, Cardiac (3) · Atrial Flutter (1) · Cardiovascular Diseases (1) · Heart Diseases (1) · Tachycardia, Ventricular (1)
Pathologic Processes (22) · Pathological Conditions, Signs and Symptoms (22) · Cardiovascular Diseases (21) · Heart Diseases (21) · Arrhythmias, Cardiac (19) · Cardiac Conduction System Disease (1) · Tachycardia (1)
Drug Delivery Systems (2) · Catheters (1) · Flecainide (1) · Patient Positioning (1)
Medtronic Cardiac Ablation Solutions (4) · Boston Scientific Corporation (3) · Shanghai MicroPort EP MedTech Co., Ltd. (3) · Abbott Medical Devices (1) · Changhai Hospital (1) · China National Center for Cardiovascular Diseases (1) · Corsano Health B.V. (1) · Hangzhou Dinova EP Technology Co., Ltd (1) · Heart Rhythm Clinical and Research Solutions, LLC (1) · InCarda Therapeutics, Inc. (1) · Kardium Inc. (1) · Mitera Hospital (1) · National Taiwan University Hospital (1) · Shenyang Northern Hospital (1) · Universitair Ziekenhuis Brussel (1)
China (7) · United States (5) · Belgium (4) · Czechia (3) · Australia (2) · Croatia (2) · France (2) · Germany (2) · Greece (2) · Italy (2) · Netherlands (2) · Poland (2) · Spain (2) · Canada (1) · Hungary (1)
Amber Miller (1) · Andrea Natale, M.D. (1) · Andrea Natale, MD (1) · Bradley P. Knight, MD, FACC, FHRS (1) · Domenico G Della Rocca, MD, PhD (1) · Eelko Ronner, MD, PhD (1) · Gerhard Hindricks, Prof. (1) · Jason Andrade, Prof. (1) · Khaldoun Tarakji, MD (1) · Liqun Wu, PHD, MD (1) · Luiz Belardinelli, MD (1)