22 recruiting, 20 completed, 10 unknown, 5 withdrawn. 17 Phase 2, 16 Not applicable, 10 Phase 1, 2 Phase 3, 1 Early Phase 1.
Follow Pancreas Adenocarcinoma: new trials by email Literature Review of Pancreas Adenocarcinoma trials Research Report on Pancreas Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC certepetide, nab-paclitaxel, gemcitabine - Pancreas Cancer, Pancreatic Carcinoma | Phase 1 / Phase 2 | Withdrawn | Lisata Therapeutics, Inc. | 2030-01-01 | 2025-06-06 | |
| Hepatic Artery Infusion Pump Chemotherapy for Liver Metastases From Resected Pancreatic and Duodenal Adenocarcinoma Hepatic Artery Infusion Pump (HAIP), Floxuridine (FUDR) - Pancreas Cancer With Hepatic Metastase, Pancreas Adenocarcinoma | Recruiting | AdventHealth | 10 | 2026-11-01 | 2026-09-29 | |
| A Liquid Biopsy for Pancreatic Cancer Early-detection and Disease Monitoring PANXEON - Familial Pancreatic Cancer, Familial Pancreatic Carcinoma | Recruiting | Università Vita-Salute San Raffaele | 600 | 2026-06-03 | 2026-07-14 | |
| Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels Sequential cytoreductive intervention, Signatera Genome ultra-sensitive ctDNA blood test - Foregut Adenocarcinoma, Esophageal Adenocarcinoma | Phase 2 | Recruiting | Yale University | 54 | 2026-06-02 | 2026-09-08 |
| 24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC Nab-paclitaxel + Gemcitabine, modified FOLFIRINOX (mFOLFIRINOX) - Pancreas Adenocarcinoma | Phase 2 | Recruiting | Dartmouth-Hitchcock Medical Center | 35 | 2025-09-29 | 2026-08-06 |
| Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) HOP bundle - Pancreas Head Cancer, Pancreas Adenocarcinoma | Phase 4 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 400 | 2025-09-01 | 2025-12-22 |
| Neoadjuvant vs Upfront Surgery for Resectable Pancreatic Cancer and Periampullary Cancer Neoadjuvant chemotherapy, Upfront Surgery Group - Pancreas Cancer, Periampullary Cancer | Phase 3 | Recruiting | Minia University | 262 | 2025-07-20 | 2026-09-11 |
| Predictive Risk Factors for Pancreatic Fistula After Pancreaticoduodenectomy pancreaticoduodenectomy procedure - Pancreas Cancer, Pancreas Neoplasm | Not applicable | Recruiting | Minia University | 100 | 2025-06-20 | 2026-07-01 |
| CAPEcitabine eXtension of Adjuvant Therapy for Pancreatic Adenocarcinoma: (CAPE-X) Capecitabine - Pancreas Cancer, Pancreas Adenocarcinoma | Phase 2 | Withdrawn | Case Comprehensive Cancer Center | 2024-12-01 | 2024-08-15 | |
| THE-0504 in Patients With Solid Tumors THE-0504 - Small Cell Lung Cancer (SCLC), Colorectal Carcinoma (CRC) | Phase 1 | Recruiting | Thena Biotech S.r.l. | 30 | 2024-11-13 | 2026-06-12 |
| The Application of DNA Nanomachines for Detecting microRNA in Blood for the Diagnosis of Pancreatic Cancer. Diagnosis of Pancreatic Cancer MicroRNA (mir-642b-3p) - Pancreas Adenocarcinoma, MicroRNA | Unknown | National Taiwan University Hospital | 30 | 2024-07-06 | 2024-07-12 | |
| Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer CB CAR-NK18.2, Cyclophosphamide, Fludarabine - Gastric Cancer, Pancreas Adenocarcinoma | Phase 1 | Completed | Zhejiang Provincial People's Hospital | 9 | 2024-07-03 | 2026-07-09 |
| The Role of the Human Microbiome in Patients After Pancreatic Resection. Pancreatic resection - Pancreas Cancer, Pancreas Neoplasm | Enrolling by invitation | St. Antonius Hospital | 200 | 2024-06-01 | 2026-04-27 | |
| This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors ZM008 - Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Zumutor Biologics Inc. | 100 | 2024-05-22 | 2026-04-02 |
| NIR-Fluorescence Guided Surgical Resection of Neoadjuvant Treated Localized Pancreatic Cancer Using SGM-101 Fluorescence-guided surgery using CEA-targeted fluorophore SGM-101 - Pancreas Adenocarcinoma | Phase 2 | Recruiting | Leiden University Medical Center | 20 | 2024-03-18 | 2024-04-04 |
| A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors IMM-6-415 - Advanced Solid Tumor (Phase 1), Pancreas Adenocarcinoma | Phase 1 / Phase 2 | Completed | Immuneering Corporation | 30 | 2024-02-27 | 2025-05-28 |
| Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX Pancreatic resection and non-anatomic liver resections. - Pancreas Adenocarcinoma, Pancreas Metastases | Not applicable | Recruiting | Laval University | 15 | 2024-01-16 | 2024-04-16 |
| Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy Multiplex PCR-test for circulating tumor DNA - Metastatic Colorectal Cancer, Pancreas Adenocarcinoma | Terminated | Oslo University Hospital | 16 | 2024-01-15 | 2026-01-29 | |
| Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis Long term survival multimodal analysis - Pancreas Adenocarcinoma, Small-cell Lung Cancer | Recruiting | Cure 51 | 1020 | 2023-11-01 | 2023-12-07 | |
| Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer PALN resection - Pancreas Cancer, Pancreas Adenocarcinoma | Not applicable | Recruiting | Jon Unosson | 300 | 2023-09-05 | 2023-10-04 |
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Pancreatic Neoplasms (34) · Colorectal Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Cholangiocarcinoma (3) · Pancreatic Diseases (3) · Stomach Neoplasms (3) · Duodenal Neoplasms (2) · Melanoma (2) · Neoplasms (2) · Pancreatic Cyst (2) · Pancreatic Fistula (2) · Small Cell Lung Carcinoma (2) · Squamous Cell Carcinoma of Head and Neck (2) · Triple Negative Breast Neoplasms (2) · Adenocarcinoma (1)
Neoplasms (44) · Neoplasms by Site (44) · Digestive System Diseases (41) · Digestive System Neoplasms (41) · Endocrine Gland Neoplasms (36) · Endocrine System Diseases (36) · Pancreatic Diseases (32) · Neoplasms by Histologic Type (12) · Gastrointestinal Diseases (10) · Gastrointestinal Neoplasms (10) · Neoplasms, Glandular and Epithelial (10) · Pathological Conditions, Signs and Symptoms (9) · Carcinoma (7) · Intestinal Diseases (7) · Intestinal Neoplasms (7)
Gemcitabine (9) · 130-nm albumin-bound paclitaxel (5) · Radiosurgery (4) · Albumin-Bound Paclitaxel (2) · Fluorouracil (2) · Irinotecan (2) · Leucovorin (2) · Oxaliplatin (2) · Taxes (2) · pembrolizumab (2) · Antibodies (1) · Biopsy (1) · Biopsy, Fine-Needle (1) · Capecitabine (1) · Cyclophosphamide (1)
Laval University (2) · Leiden University Medical Center (2) · Minia University (2) · The Cooper Health System (2) · Wake Forest University Health Sciences (2) · Yale University (2) · Zhejiang University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Adenocyte, LLC (1) · AdventHealth (1) · Ajou University School of Medicine (1) · Asana BioSciences (1) · CNAO National Center of Oncological Hadrontherapy (1) · Campus Bio-Medico University (1) · Capital Health System, Inc (1)
United States (21) · Italy (9) · China (7) · Canada (5) · Netherlands (5) · France (3) · South Korea (3) · United Kingdom (3) · Egypt (2) · Germany (2) · Hungary (2) · Sweden (2) · Switzerland (2) · Australia (1) · Austria (1)
Michele Reni, MD (2) · Saleh K Saleh, MD (2) · Alessandro Mannucci, MD (1) · Alexandre Brind'Amour, MD (1) · Alexandre Brind'Amour, MD, MSc (1) · Ashwin Somasundaram, MD (1) · Britt-Marie Karlson (1) · Carl DeSelm, M.D., Ph.D. (1) · Christopher W Teshima, MD,FRCPC (1) · Daniel C. Chung, MD (1) · Daniel D Von Hoff, MD, FACS (1) · Daniel Helbling, Dr. Med. (1) · Francesca Valvo, MD (1) · Gennaro Daniele (1)
PMID 12297746, PMID 15886696, PMID 16083707, PMID 17872573, PMID 19111249, PMID 21458985, PMID 21654538, PMID 24840647, PMID 26492440, PMID 26777407, PMID 28108468, PMID 31521134, PMID 33444177, PMID 34176743, PMID 36479231, PMID 37598000, PMID 37735664, PMID 37787643, PMID 38176719, PMID 39462835, PMID 39846984, PMID 40448572, PMID 40509918, PMID 40914176, PMID 40971231, PMID 41307673
2023 (2), 2019 (1), P30CA012197 (1), R01CA248917 (1), U01CA243695 (1)