3 completed, 3 unknown, 1 enrolling by invitation, 1 recruiting. 8 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 3, Unknown 3, Enrolling by invitation 1, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Oligospermia: new trials by email Literature Review of Oligospermia trials Research Report on Oligospermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm isotretinoin, Human chorionic gonadotrophin (hCG) - Oligospermia, Azoospermia, Nonobstructive | Phase 2 | Enrolling by invitation | University of Nebraska | 100 | 2026-04-13 | 2026-04-20 |
| Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg® Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months. - Azoospermia, Nonobstructive, Teratospermia | Phase 1 / Phase 2 | Recruiting | Lomonosov Moscow State University Medical Research and Educational Center | 80 | 2024-11-26 | 2025-03-11 |
| Comparative Evaluation of the Efficacy of Letrozole, L-Carnitine, and Their Combination on Sperm Quality, Oxidative Stress, and ART Outcomes in Men With Idiopathic Oligoasthenoteratozoospermia. Letrozole 2.5mg, L-carnitine - Idiopathic Oligoasthenoteratozoospermia, Male Infertility | Phase 2 / Phase 3 | Completed | Tehran University of Medical Sciences | 90 | 2023-12-01 | 2026-06-30 |
| Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility Tab Tamoxifen 10 mg, Tab Tamoxifen 10mg,Cap vitamin E 400mg - Oligoasthenoteratozoospermia, Male Infertility | Phase 2 | Unknown | Sharif Medical Research Center | 110 | 2021-10-15 | 2022-01-21 |
| Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility Lipoaspiration and SVF introduction., Standard therapy. - Azoospermia, Oligozoospermia | Phase 2 | Unknown | State-Financed Health Facility "Samara Regional Medical Center Dinasty" | 40 | 2018-03-12 | 2020-10-22 |
| 7 NUTS Study. Diet Modification and Male Fertility. 7 nuts a day, Diet modification - Male Subfertility, Oligospermia | Phase 2 / Phase 3 | Unknown | A.O.U. Città della Salute e della Scienza | 100 | 2014-05-01 | 2014-05-28 |
| A Clinical Trial to Study the Safety and Efficacy of Chandrakanthi Choornam in Patients With Low Sperm Count Chandrakanthi Choornam (CKC) - Oligospermia | Phase 2 | Completed | Tamil Nadu Dr.M.G.R.Medical University | 40 | 2012-12-01 | 2014-09-09 |
| The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm Count Lisinopril - Oligospermia | Phase 2 | Completed | University Of Nigeria Teaching Hospital | 33 | 1998-03-01 | 2013-11-25 |
Infertility, Male (5) · Azoospermia (2) · Azoospermia, Nonobstructive (2) · Teratozoospermia (2) · Asthenozoospermia (1) · Infertility (1)
Genital Diseases (8) · Genital Diseases, Male (8) · Male Urogenital Diseases (8) · Urogenital Diseases (8) · Infertility (7) · Infertility, Male (3)
Carnitine (1) · Chorionic Gonadotropin (1) · Clomiphene (1) · Diet Therapy (1) · Diet, Healthy (1) · Injections (1) · Isotretinoin (1) · Letrozole (1) · Lisinopril (1) · Standard of Care (1) · Tamoxifen (1)
A.O.U. Città della Salute e della Scienza (1) · Lomonosov Moscow State University Medical Research and Educational Center (1) · Sharif Medical Research Center (1) · State-Financed Health Facility "Samara Regional Medical Center Dinasty" (1) · Tamil Nadu Dr.M.G.R.Medical University (1) · Tehran University of Medical Sciences (1) · University Of Nigeria Teaching Hospital (1) · University of Nebraska (1)
Russia (2) · India (1) · Iran (1) · Italy (1) · Nigeria (1) · Pakistan (1) · United States (1)
Aldo Maina, MD (1) · Anastasia Efimenko, doctor of sciences (1) · Anees Fatima, MBBS,FCPS (1) · Anthony U Mbah, MD, FMCP (1) · Azim Hedayatpour, Professor, PhD (1) · Chris Deibert, MD, MPH (1) · Dmitry Okhobotov, doctor of sciences (1) · Dr.B. Akila., M.D (s) (1) · Olga Tyumina, M.D. P.h.D. (1)
PMID 11228933, PMID 12516764, PMID 19381855, PMID 22081410, PMID 23757979, PMID 25274200, PMID 25456165, PMID 8973665