6 completed, 4 terminated, 2 active not recruiting, 2 unknown. 6 Phase 2, 3 Phase 1, 2 Not applicable, 2 Phase 3, 1 Early Phase 1.
Follow Oligoastrocytoma: new trials by email Literature Review of Oligoastrocytoma trials Research Report on Oligoastrocytoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma exHSC, Nivolumab, Resection or biopsy - Recurrent High-grade Glioma, Grade III Astrocytoma | Phase 1 | Active not recruiting | University of Florida | 12 | 2025-07-25 | 2026-09-23 |
| Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy - Anaplastic Astrocytoma, IDH-Wildtype, Anaplastic Oligoastrocytoma | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 40 | 2020-01-30 | 2026-07-16 |
| Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma Biospecimen Collection, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis - Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma | Phase 2 | Active not recruiting | NRG Oncology | 120 | 2018-01-23 | 2026-07-28 |
| NovoTTF-200A Device in Treating Patients With Newly Diagnosed High Risk Oligodendroglioma Wear novoTTF-200A, Quality-of-Life Assessment - Anaplastic Oligodendroglioma, Oligoastrocytoma | Not applicable | Withdrawn | University of Southern California | 2017-12-15 | 2020-12-10 | |
| Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved Palbociclib - Oligodendroglioma, Oligoastrocytoma | Phase 2 | Completed | Grupo Español de Investigación en Neurooncología | 34 | 2015-10-25 | 2024-11-22 |
| A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas Temozolomide - Astrocytoma, Oligodendroglioma | Phase 2 | Unknown | Huashan Hospital | 54 | 2014-06-01 | 2019-02-21 |
| Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas Astrocytoma, Oligodendroglioma | Terminated | Dartmouth-Hitchcock Medical Center | 94 | 2013-10-09 | 2025-09-15 | |
| Neural Basis of Language Processing fMRI, tractography, neuropsychological examination - Oligoastrocytoma, Astrocytoma | Not applicable | Completed | University Hospital, Montpellier | 63 | 2012-09-01 | 2020-09-02 |
| (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas Low Grade Glioma, Glioblastoma Multiforme | Terminated | National Cancer Institute (NCI) | 2 | 2011-01-13 | 2018-07-05 | |
| HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas Peptide vaccine + Poly-ICLC - Astrocytoma, Oligoastrocytoma | Early Phase 1 | Completed | Ian F. Pollack, M.D. | 10 | 2009-04-01 | 2015-12-08 |
| FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma Astrocytoma, Oligoastrocytoma | Unknown | Ludwig-Maximilians - University of Munich | 38 | 2008-06-01 | 2015-09-22 | |
| Treatment Strategy for Low-grade Gliomas Radiation therapy, Temozolomide - Astrocytomas, Oligodendrogliomas | Phase 3 | Terminated | Sun Yat-sen University | 500 | 2007-12-01 | 2014-08-05 |
| A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma Temozolomide and O6-Benzylguanine - Glioma, Astrocytoma | Phase 2 | Terminated | Keryx / AOI Pharmaceuticals, Inc. | 32 | 2006-10-01 | 2012-02-09 |
| Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors Carboplatin, Etoposide, Etoposide Phosphate - Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma | Phase 1 / Phase 2 | Completed | OHSU Knight Cancer Institute | 33 | 2005-09-15 | 2022-03-17 |
| IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma IL13-PE38QQR, Surgery for placement, Radiation therapy - Glioblastoma Multiforme, Anaplastic Astrocytoma | Phase 1 | Completed | INSYS Therapeutics Inc | 24 | 2004-07-01 | 2011-07-04 |
| Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide Temozolomide, Focal radiotherapy - Anaplastic Astrocytoma, Oligodendroglioma | Phase 3 | Completed | Neuro-Oncology Working Group of the German Cancer Society | 318 | 1999-06-01 | 2008-07-17 |
Astrocytoma (16) · Oligodendroglioma (15) · Glioma (6) · Glioblastoma (5) · Brain Neoplasms (3) · Ependymoma (1) · Neoplasms (1)
Neoplasms by Histologic Type (16) · Neoplasms, Germ Cell and Embryonal (16) · Neoplasms, Glandular and Epithelial (16) · Neoplasms, Nerve Tissue (16) · Neoplasms, Neuroepithelial (16) · Neuroectodermal Tumors (16) · Neoplasms (15) · Glioma (10) · Brain Diseases (3) · Central Nervous System Diseases (3) · Central Nervous System Neoplasms (3) · Neoplasms by Site (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3)
Temozolomide (7) · Radiotherapy (3) · Biopsy (1) · Carboplatin (1) · Diffusion Tensor Imaging (1) · Drug Implants (1) · Equipment and Supplies (1) · Etoposide (1) · IL13-PE38 (1) · Magnetic Resonance Imaging (1) · Magnetic Resonance Spectroscopy (1) · Mannitol (1) · Melphalan (1) · Neuropsychological Tests (1) · Nivolumab (1)
Dartmouth-Hitchcock Medical Center (1) · Grupo Español de Investigación en Neurooncología (1) · Huashan Hospital (1) · INSYS Therapeutics Inc (1) · Ian F. Pollack, M.D. (1) · Keryx / AOI Pharmaceuticals, Inc. (1) · Ludwig-Maximilians - University of Munich (1) · M.D. Anderson Cancer Center (1) · NRG Oncology (1) · National Cancer Institute (NCI) (1) · Neuro-Oncology Working Group of the German Cancer Society (1) · OHSU Knight Cancer Institute (1) · Sun Yat-sen University (1) · University Hospital, Montpellier (1) · University of Florida (1)
United States (10) · China (2) · Germany (2) · Spain (1)
Arti B Gaur, PhD (1) · David R Grosshans (1) · Debra N Yeboa (1) · Edward A Neuwelt (1) · Frank Lieberman, MD (1) · Jennifer Quinn, MD (1) · Jinsong Wu, Professor (1) · Joerg C. Tonn, Prof. Dr. (1) · John Ligon, MD (1) · Michael Weller, MD (1) · Teri N Kreisl, M.D. (1) · Thomas Chen, MD (1) · Wolfgang Wick, MD (1) · Zhongping Chen, M.D., Ph.D. (1)
P30CA014089 (1), R21CA133859 (1), U10CA180868 (1)