9 completed, 2 terminated, 1 withdrawn. 12 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 9, Terminated 2, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
Follow Noncutaneous Extranodal Lymphoma: new trials by email Literature Review of Noncutaneous Extranodal Lymphoma trials Research Report on Noncutaneous Extranodal Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies cyclophosphamide, fludarabine phosphate, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 2 | Withdrawn | University of Medicine and Dentistry of New Jersey | 2014-01-01 | 2016-07-14 | |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas brentuximab vedotin, rituximab, laboratory biomarker analysis - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Terminated | Northwestern University | 20 | 2013-03-05 | 2021-09-01 |
| Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant lenalidomide, rituximab, pharmacological study - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 3 | 2012-05-01 | 2017-07-27 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies deferasirox, laboratory biomarker analysis, enzyme-linked immunosorbent assay - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Wake Forest University Health Sciences | 16 | 2011-01-01 | 2018-09-07 |
| Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Akt inhibitor MK2206, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2010-12-01 | 2020-11-04 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer fludarabine phosphate, total-body irradiation, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 150 | 2004-04-01 | 2020-01-29 |
| Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2003-09-01 | 2020-01-18 |
| Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies gemcitabine hydrochloride, carboplatin, dexamethasone - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | Fred Hutchinson Cancer Center | 55 | 2003-08-01 | 2017-06-29 |
| Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer total-body irradiation, fludarabine phosphate, cyclosporine - Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 21 | 2000-05-01 | 2020-01-21 |
Immunoblastic Lymphadenopathy (12) · Leukemia, Lymphocytic, Chronic, B-Cell (12) · Lymphoma, B-Cell, Marginal Zone (12) · Lymphoma, Extranodal NK-T-Cell (12) · Lymphoma, Follicular (12) · Lymphoma, Large B-Cell, Diffuse (12) · Lymphoma, Large-Cell, Anaplastic (12) · Lymphoma, Large-Cell, Immunoblastic (12) · Lymphoma, Mantle-Cell (12) · Lymphoma, Non-Hodgkin (12) · Lymphoma, T-Cell, Cutaneous (12) · Lymphoma, T-Cell, Peripheral (12) · Mycosis Fungoides (12) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (12) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (12)
Blood Protein Disorders (12) · Cardiovascular Diseases (12) · Chronic Disease (12) · Disease Attributes (12) · Hematologic Diseases (12) · Hemic and Lymphatic Diseases (12) · Hemorrhagic Disorders (12) · Hemostatic Disorders (12) · Immune System Diseases (12) · Immunoproliferative Disorders (12) · Leukemia (12) · Leukemia, B-Cell (12) · Leukemia, Lymphoid (12) · Lymphadenopathy (12) · Lymphatic Diseases (12)
Peripheral Blood Stem Cell Transplantation (6) · Whole-Body Irradiation (6) · fludarabine phosphate (6) · Mycophenolic Acid (5) · Cyclosporine (4) · Rituximab (3) · Cyclophosphamide (2) · Tacrolimus (2) · Alemtuzumab (1) · Brentuximab Vedotin (1) · Busulfan (1) · Calcium Dobesilate (1) · Carboplatin (1) · Cord Blood Stem Cell Transplantation (1) · Deferasirox (1)
Fred Hutchinson Cancer Center (7) · National Cancer Institute (NCI) (1) · Northwestern University (1) · University of Chicago (1) · University of Medicine and Dentistry of New Jersey (1) · Wake Forest University Health Sciences (1)
United States (12) · Italy (4) · Germany (1)
Brenda Sandmaier (2) · David Maloney (2) · Adam Petrich, MD (1) · Ajay Gopal (1) · Hongtao Liu (1) · Marco Mielcarek (1) · Mary Ann Knovich, MD (1) · Mohamed Sorror (1) · Roger Strair (1) · Yasuhiro Oki (1)
PMID 32499241, PMID 26213141, PMID 26764356
P30CA015704 (6), P01CA018029 (2), P01CA078902 (2), N01CM00039 (1), N01CM62202 (1), P30CA016672 (1), P30CA072720 (1)