5 completed, 2 withdrawn, 1 not yet recruiting, 1 unknown. 9 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 5, Withdrawn 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 2, Withdrawn 1 |
Follow Nevus: new trials by email Literature Review of Nevus trials Research Report on Nevus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies Everolimus - Vascular Malformations, Arteriovenous Malformations | Phase 2 | Not yet recruiting | Yonsei University | 67 | 2026-04-01 | 2026-03-17 |
| 12-week Study of NFX-179 Gel in Subjects With Epidermal Nevi NFX-179 Gel 1.50% - Epidermal Nevi, Nevus Sebaceus | Phase 2 | Withdrawn | Albert Chiou | 2023-06-01 | 2024-05-28 | |
| Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) 6MHP, NeoAg-mBRAF, PolyICLC - Melanoma, Ocular Melanoma | Phase 1 / Phase 2 | Completed | Craig L Slingluff, Jr | 22 | 2020-09-28 | 2024-07-16 |
| A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome KRN23 - Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome | Phase 2 | Completed | Kyowa Kirin Co., Ltd. | 14 | 2016-04-01 | 2022-09-06 |
| Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS) Burosumab - Tumor Induced Osteomalacia (TIO), Epidermal Nevus Syndrome (ENS) | Phase 2 | Completed | Kyowa Kirin, Inc. | 17 | 2015-03-24 | 2024-05-06 |
| The Effects of Autologous Fat Transfer on Preventing Expanded Skin From Expansion Failure Fat grafting - Scar, Nevus | Phase 1 / Phase 2 | Completed | Shanghai Jiao Tong University School of Medicine | 80 | 2011-01-01 | 2016-06-22 |
| Photochemical Tissue Bonding tissue bonding, sutures - Basal Cell Carcinoma, Squamous Cell Carcinoma | Phase 2 | Completed | Massachusetts General Hospital | 40 | 2007-09-01 | 2009-04-10 |
| Evaluation of 20% Betulinic Acid Ointment for Treatment of Dysplastic Nevi (Moderate to Severe Dysplasia) 20% betulinic acid ointment, BA - Dysplastic Nevus Syndrome | Phase 1 / Phase 2 | Withdrawn | University of Illinois at Chicago | 2006-01-01 | 2021-06-28 | |
| A Trial to Investigate Scar Improvement Efficacy of RN1001 (Avotermin) After Head and Neck Naevi Excision Avotermin - Nevus, Cicatrix | Phase 2 | Unknown | Renovo | 239 | 2004-04-01 | 2008-04-11 |
Nevus, Sebaceous of Jadassohn (3) · Cicatrix (2) · Dysplastic Nevus Syndrome (2) · Oncogenic osteomalacia (2) · Arteriovenous Malformations (1) · Carcinoma, Basal Cell (1) · Carcinoma, Squamous Cell (1) · Hemangioendothelioma (1) · Hemangioma (1) · Lymphangioma (1) · Melanoma (1) · Skin Neoplasms (1) · Uveal Melanoma (1) · Vascular Malformations (1)
Neoplasms (9) · Neoplasms by Histologic Type (9) · Nevi and Melanomas (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Congenital Abnormalities (4) · Abnormalities, Multiple (3) · Nervous System Diseases (3) · Neurocutaneous Syndromes (3) · Fibrosis (2) · Genetic Diseases, Inborn (2) · Neoplasms by Site (2) · Neoplastic Syndromes, Hereditary (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2)
burosumab (2) · Betulinic Acid (1) · Everolimus (1) · Sutures (1) · TGFB3 protein, human (1)
Albert Chiou (1) · Craig L Slingluff, Jr (1) · Kyowa Kirin Co., Ltd. (1) · Kyowa Kirin, Inc. (1) · Massachusetts General Hospital (1) · Renovo (1) · Shanghai Jiao Tong University School of Medicine (1) · University of Illinois at Chicago (1) · Yonsei University (1)
United States (5) · China (1) · Japan (1) · South Korea (1) · United Kingdom (1)
Albert S Chiou, MD, MBA (1) · Craig L. Slingluff, Jr., MD (1) · Irene E Kochevar, PhD (1) · Jim Bush, MB ChB (1) · Tapas K. Das Gupta, MD, PhD, DSc (1)