5 recruiting, 3 not yet recruiting, 1 completed. 2 Phase 1, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Neuromyelitis Optica Spectrum Disorders (NMOSD): new trials by email Literature Review of Neuromyelitis Optica Spectrum Disorders (NMOSD) trials Research Report on Neuromyelitis Optica Spectrum Disorders (NMOSD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter Prospective Real-World Effectiveness and Safety of Satralizumab in the Early Treatment of Attacks in NMOSD Satralizumab - Neuromyelitis Optica Spectrum Disorders (NMOSD) | Recruiting | Junwei Hao, MD | 50 | 2026-07-20 | 2026-08-13 | |
| Crisugabalin in NMOSD Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial Crisugabalin, Placebo+Crisugabalin - Neuromyelitis Optica Spectrum Disorders (NMOSD), Neuropathic Pain | Phase 4 | Not yet recruiting | Tang-Du Hospital | 110 | 2026-06-15 | 2026-07-13 |
| A Study of C-CAR168 in the Treatment of Central Nervous System Autoimmune Diseases Refractory to Standard Therapy CD20/BCMA-directed CAR-T cells - Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorders (NMOSD) | Phase 1 | Not yet recruiting | Huashan Hospital | 15 | 2026-02-01 | 2026-01-15 |
| Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder Eculizumab administration, High-dose corticosteroid pulse therapy, Plasma exchange (PE) - Neuromyelitis Optica Spectrum Disorders (NMOSD) | Phase 3 | Recruiting | Tianjin Medical University General Hospital | 198 | 2026-01-01 | 2026-05-14 |
| Slow vs. Rapid Glucocorticoids Tapering With Inebilizumab in NMOSD Slow-tapering glucocorticoids + Inebilizumab, Rapid-tapering glucocorticoids + Inebilizumab - Neuromyelitis Optica (NMO), Neuromyelitis Optica Spectrum Disorders (NMOSD) | Phase 3 | Not yet recruiting | Tianjin Medical University General Hospital | 170 | 2025-09-01 | 2025-08-20 |
| HANDLE-a Real World Study on Satralizumab in NMOSD Satralizumab - Neuromyelitis Optica Spectrum Disorders (NMOSD) | Recruiting | Huashan Hospital | 100 | 2025-03-31 | 2026-09-18 | |
| Cohort Study on Neuroimmune Diseases in the Reproductive Age Neuromyelitis Optica Spectrum Disorders (NMOSD), Multiple Sclerosis | Recruiting | Third Affiliated Hospital, Sun Yat-Sen University | 100 | 2024-04-21 | 2026-06-17 | |
| A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy CD20/BCMA-directed CAR-T cells - Systemic Lupus Erythematosus (SLE), Immune-mediated Necrotizing Myopathy (IMNM) | Phase 1 | Recruiting | RenJi Hospital | 30 | 2024-03-20 | 2025-07-25 |
| BLAZE-Limiting Approach in NMOSD Eculizumab administration - Neuromyelitis Optica Spectrum Disorders (NMOSD) | Completed | Huashan Hospital | 9 | 2023-10-01 | 2025-03-21 |
Neuromyelitis Optica (9) · Multiple Sclerosis (3) · Autoimmune Diseases of the Nervous System (2) · Myasthenia Gravis (2) · Guillain-Barre Syndrome (1) · Lupus Erythematosus, Systemic (1) · Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (1) · Neuralgia (1) · Optic Neuritis (1) · Scleroderma, Systemic (1) · Stiff-Person Syndrome (1)
Autoimmune Diseases (9) · Cranial Nerve Diseases (9) · Demyelinating Autoimmune Diseases, CNS (9) · Demyelinating Diseases (9) · Eye Diseases (9) · Immune System Diseases (9) · Myelitis, Transverse (9) · Nervous System Diseases (9) · Optic Nerve Diseases (9) · Optic Neuritis (8) · Autoimmune Diseases of the Nervous System (7) · Neuromuscular Diseases (4) · Neoplasms (2) · Neoplasms by Site (2) · Nervous System Neoplasms (2)
satralizumab (2) · Plasma Exchange (1) · inebilizumab (1)
Huashan Hospital (3) · Tianjin Medical University General Hospital (2) · Junwei Hao, MD (1) · RenJi Hospital (1) · Tang-Du Hospital (1) · Third Affiliated Hospital, Sun Yat-Sen University (1)
China (7)
Chao Quan, Doctor (2) · Jingzi Zhangbao, Doctor (1) · Jun Guo (1) · Junwei Hao, MD, PhD (1) · Lei Zhou (1) · Nan Shen, MD & PhD (1) · Qiang Dong, Doctor (1) · Wenjuan Huang, Doctor (1)