50 completed, 25 unknown, 21 recruiting, 10 not yet recruiting. 117 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 117 | Completed 50, Unknown 25, Recruiting 21, Not yet recruiting 10, Withdrawn 4, Terminated 3, Active not recruiting 2, Enrolling by invitation 1, Suspended 1 |
Follow Nephritis: new trials by email Literature Review of Nephritis trials Research Report on Nephritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe Proteinuria Electronic Health Record alert - Referral and Consultation, Glomerulonephritis | Not applicable | Not yet recruiting | Geisinger Clinic | 1200 | 2026-11-01 | 2026-05-12 |
| Single-cell RNA Sequencing (scRNA-seq) to Investigate the Mechanisms Underlying the Induction of Regulatory T Cells in Patients With Extramembranous Glomerulonephritis Treated With Rituximab Peripheral blood immune-cell profiling by single-cell RNA sequencing and in vitro pathway modulation assays - Membranous Nephropathy, Membranous Nephropathy - PLA2R Induced | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 12 | 2026-10-31 | 2026-09-10 |
| Lupus Nephritis Care Pathway Lupus Nephritis (LN) Care Pathway - Lupus Nephritis (LN) | Not applicable | Recruiting | Duke University | 25 | 2026-10-14 | 2026-10-19 |
| MYTP01 for Immune-Mediated Diseases MYTP01, MYTP01 Placebo - IgA Nephropathy, Kidney Transplant Recipients | Not applicable | Not yet recruiting | Zhejiang Provincial People's Hospital | 160 | 2026-10-01 | 2026-10-28 |
| Universal STAR-T Cell Injection in Autoimmune Kidney Diseases Universal STAR-T Cell - IgA Nephropathy (IgAN), Primary Membranous Nephropathy | Not applicable | Not yet recruiting | Guangdong Provincial People's Hospital | 24 | 2026-08-31 | 2026-08-10 |
| To Assess the Efficacy and Safety of Utilizing Galactose-deficient IgA1 Biomarker Changes to Guide Pathogenic IgA-targeted Therapeutic Strategies Gd-IgA1 monitoring - IgA Nephropathy (IgAN), Henoch Schönlein Purpura Nephritis | Not applicable | Recruiting | Hong Zhang | 374 | 2026-08-24 | 2026-09-16 |
| Application of the AI Platform iLN Based on DeepSeek in the Teaching of Lupus Nephritis An iLN interactive teaching platform, PPT - Learning | Not applicable | Not yet recruiting | Nanjing University | 50 | 2026-07-01 | 2026-07-16 |
| Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis Therapeutic Drug Monitoring, Standard clinical care - Systemic Lupus Erythematosus, Lupus Nephritis | Not applicable | Not yet recruiting | Federal University of Maranhao | 100 | 2026-07-01 | 2026-03-25 |
| A Study to Evaluate MTM-H-001 Injection in Adult Patients With B-Cell-Related Autoimmune Diseases MTM-H-001 Injection - Systemic Lupus Erthematosus (SLE), Lupus Nephritis (LN) | Not applicable | Not yet recruiting | Beijing GoBroad Hospital | 75 | 2026-06-01 | 2026-05-18 |
| Rituximab Combining With Low-Dose Mycophenolate Mofetil on Proliferative Lupus Nephritis in Children rituximab, Mycophenolate Mofetil (MMF) Treatment, Cyclophosphamide - Lupus Nephritis | Not applicable | Not yet recruiting | Nanfang Hospital, Southern Medical University | 112 | 2026-06-01 | 2026-06-30 |
| The Role of Transforming Growth Factor- Beta (TGF- β) Expression in Renal Biopsy of Lupus Nephritis Patients renal biopsy - Lupus Nephritis (LN) | Not applicable | Active not recruiting | Ain Shams University | 30 | 2026-05-31 | 2026-09-16 |
| CHT105 for the Treatment of Refractory Lupus Nephritis anti-CD19/70 CAR T cells (CHT105) - Systemic Lupus Erythematosus, Lupus Nephritis | Not applicable | Enrolling by invitation | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 14 | 2026-04-22 | 2026-06-18 |
| Autoimmune Protocol Diet Intervention on Proteinuria in IgA Nephropathy Patients Low inflammation diet intervention - IgA Nephropathy (IgAN) | Not applicable | Withdrawn | University of California, Los Angeles | 2026-02-01 | 2026-07-27 | |
| The Randomized Controlled Study of Shenqi Yishen Granules in the Treatment of IgA Nephropathy Shenqi Yishen Granules, Placebo - IgA Nephropathy (IgAN) | Not applicable | Not yet recruiting | Keda Lu | 102 | 2026-01-01 | 2026-01-22 |
| Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous Nephropathy Flow-cytometry tetramer-based antigen-bait assay - Membranous Nephropathy | Not applicable | Completed | Mario Negri Institute for Pharmacological Research | 48 | 2025-09-22 | 2026-03-20 |
| Identification and Characterisation of IgA With Nephritogenic Potential in IgA Deposition Nephropathies (Rep-IgAN) Blood sample - Kidney Disease | Not applicable | Recruiting | University Hospital, Limoges | 150 | 2025-06-25 | 2025-12-22 |
| SLIT ABS: Study on Patients With Autoimmune Podocytopathy Serum and renal tissue analysis - Nephrotic Syndrome With Edema (Diagnosis), Minimal Change Nephrotic Syndrome | Not applicable | Recruiting | Meyer Children's Hospital IRCCS | 50 | 2025-06-10 | 2026-04-08 |
| Finerenone in Patients With IgA-nephropathy: Prospective Interventional Trial Finerenone - IgA Nephropathy (IgAN) | Not applicable | Recruiting | Botkin Hospital | 30 | 2025-05-21 | 2025-07-09 |
| Equecabtagene Autoleucel Injection (Eque-cel) for Relapsed/Refractory Systemic Lupus Erythematosus (SLE) Equecabtagene Autoleucel Injection - Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN) | Not applicable | Recruiting | Tongji Hospital | 6 | 2025-04-05 | 2025-03-30 |
| Efficacy and Safety of Telitacicept in IgAN Telitacicept 240mg, Glucocorticoid - IgA Nephropathy (IgAN), Kidney Diseases | Not applicable | Recruiting | Ruijin Hospital | 118 | 2024-12-06 | 2025-01-01 |
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Glomerulonephritis, IGA (36) · Lupus Nephritis (33) · Glomerulonephritis, Membranous (21) · Glomerulosclerosis, Focal Segmental (12) · Lupus Erythematosus, Systemic (9) · Pyelonephritis (9) · Kidney Diseases (7) · Glomerulonephritis (6) · Nephrotic Syndrome (6) · Proteinuria (6) · Nephrosis, Lipoid (5) · Glomerulonephritis, Membranoproliferative (3) · Urinary Tract Infections (3) · Acute Kidney Injury (2) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (2)
Female Urogenital Diseases (117) · Female Urogenital Diseases and Pregnancy Complications (117) · Male Urogenital Diseases (117) · Urogenital Diseases (116) · Urologic Diseases (116) · Kidney Diseases (110) · Glomerulonephritis (99) · Immune System Diseases (95) · Autoimmune Diseases (91) · Skin and Connective Tissue Diseases (37) · Connective Tissue Diseases (36) · Lupus Erythematosus, Systemic (24) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (15)
Prednisone (11) · Tacrolimus (8) · Blood Specimen Collection (7) · Mycophenolic Acid (6) · Rituximab (5) · Cyclophosphamide (4) · Losartan (4) · Adrenal Cortex Hormones (3) · Glucocorticoids (3) · Angiotensin-Converting Enzyme Inhibitors (2) · Azathioprine (2) · Educational Status (2) · Enalapril (2) · Tonsillectomy (2) · Allopurinol (1)
Nanjing University School of Medicine (12) · Centre Hospitalier Universitaire de Nice (4) · Mario Negri Institute for Pharmacological Research (4) · Zhi-Hong Liu, M.D. (4) · Assistance Publique - Hôpitaux de Paris (3) · Centre Hospitalier Universitaire de Saint Etienne (3) · Northwell Health (3) · Ruijin Hospital (3) · Shanghai University of Traditional Chinese Medicine (3) · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (3) · Beijing Friendship Hospital (2) · Kaneka Medical America LLC (2) · RenJi Hospital (2) · St. Petersburg State Pavlov Medical University (2) · Sun Yat-sen University (2)
China (47) · United States (18) · France (15) · Italy (5) · Hong Kong (3) · Russia (3) · Sweden (3) · Egypt (2) · Mexico (2) · Slovenia (2) · Spain (2) · United Kingdom (2) · Australia (1) · Brazil (1) · Canada (1)
Zhihong Liu, Master (3) · Lei-Shi Li, M.D. (2) · Marina Noris, PhD (2) · Zhi-hong Liu, M.D. (2) · Ad Hendrikx, dr. (1) · Ahmed Boumediene, doctor (1) · Angela M Zivkovic, PhD (1) · Asha Moudgil, MD (1) · Bao Chun De (1) · Baosong Gui, MD (1) · Barbara Seitz-polski (1) · Berna Yelken, MD (1)
PMID 38724717, PMID 38299639, PMID 35224732, PMID 38864363, PMID 34778952, PMID 18596121, PMID 18930568, PMID 23787555, PMID 24086581, PMID 24707402, PMID 25383558, PMID 26032537, PMID 26672987, PMID 27088545, PMID 28143529, PMID 28763548, PMID 29500209, PMID 31067237, PMID 31340979, PMID 34721403, PMID 35579642, PMID 35788493, PMID 36283759, PMID 36745456, PMID 36853224, PMID 37068952, PMID 37456840, PMID 37926085, PMID 37947276, PMID 38096261, PMID 39768590, PMID 40581835, PMID 41563292, PMID 41830115, PMID 41905595, PMID 42536435
R01DK131091 (2), K23DK093556 (1), R01DK141114 (1), U54DK083912 (1)