13 completed, 1 active not recruiting, 1 terminated, 1 unknown. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 13, Active not recruiting 1, Terminated 1, Unknown 1 |
Follow Neoplasms, Multiple Primary: new trials by email Literature Review of Neoplasms, Multiple Primary trials Research Report on Neoplasms, Multiple Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex Cannabidiol Oral Solution [Epidiolex] - Tuberous Sclerosis Complex Associated Neuropsychiatric Disease | Phase 4 | Completed | Jazz Pharmaceuticals | 79 | 2023-06-29 | 2026-04-27 |
| A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML) Everolimus - Renal Angiomyolipoma | Phase 4 | Completed | Novartis Pharmaceuticals | 10 | 2023-05-01 | 2026-11-09 |
| Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment Alpelisib, Fulvestrant - Advanced Breast Cancer | Phase 4 | Completed | Novartis Pharmaceuticals | 40 | 2022-08-09 | 2026-07-09 |
| Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution Cannabidiol - Lennox Gastaut Syndrome, Dravet Syndrome | Phase 4 | Active not recruiting | Jazz Pharmaceuticals | 154 | 2021-07-07 | 2026-08-26 |
| Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex. Everolimus - Renal Angiomyolipoma | Phase 4 | Completed | Novartis Pharmaceuticals | 40 | 2018-11-09 | 2021-09-09 |
| GRK4 Polymorphisms Blood Pressure Response to Candesartan Candesartan - Essential Hypertension | Phase 4 | Unknown | Third Military Medical University | 500 | 2013-07-01 | 2014-11-18 |
| Effects of Growth Hormone Administration on Muscle Strength and Body Composition in Men Over 50 Years Old growth hormone - Healthy | Phase 4 | Completed | Universidade Federal do Rio de Janeiro | 13 | 2012-01-01 | 2014-09-03 |
| How Much Vitamin D is Required to be Protective Against Deficiency During the Winter Months? Vitamin D, placebo - Vitamin D Deficiency | Phase 4 | Completed | McGill University | 77 | 2011-10-01 | 2014-09-05 |
| Effects of Diet-induced Weight Loss in Obese Men Optifast, Conventional diet counseling - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 70 | 2010-12-01 | 2015-07-29 |
| Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients vigabatrin - Complex Partial Seizures | Phase 4 | Terminated | University of Pennsylvania | 1 | 2010-08-01 | 2017-07-12 |
| Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men weight loss counselling - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 90 | 2010-07-01 | 2015-07-29 |
| Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men Exercise and diet - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 70 | 2010-07-01 | 2015-07-29 |
| Doxycycline In Lymphangioleiomyomatosis (LAM) Doxycycline, Placebo - Lymphangioleiomyomatosis, Tuberous Sclerosis | Phase 4 | Completed | University of Nottingham | 24 | 2009-07-01 | 2015-12-02 |
| Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis antibiotic - Vertebral Osteomyelitis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 351 | 2006-11-01 | 2013-05-06 |
| Treatment of Zollinger-Ellison Syndrome With Prevacid Lansoprazole (Prevacid) - Zollinger-Ellison Syndrome, Multiple Endocrine Neoplasia | Phase 4 | Completed | Charles Mel Wilcox, MD | 72 | 2003-03-01 | 2012-10-30 |
| The Role of 5-alpha Reductase in Mediating Testosterone Actions Testosterone Enanthate, Dutasteride - Healthy | Phase 4 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 184 | 2002-11-01 | 2010-05-13 |
Multiple Endocrine Neoplasia Type 1 (9) · Tuberous Sclerosis (6) · Inflammation (4) · Obesity (3) · Sexual Dysfunction, Physiological (3) · Angiomyolipoma (2) · Lymphangioleiomyomatosis (2) · Seizures (2) · Behavior (1) · Discitis (1) · Epilepsies, Myoclonic (1) · Essential Hypertension (1) · Lennox Gastaut Syndrome (1) · Liver Cirrhosis (1) · Multiple Endocrine Neoplasia (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Genetic Diseases, Inborn (16) · Neoplasms (16) · Neoplastic Syndromes, Hereditary (16) · Endocrine Gland Neoplasms (10) · Endocrine System Diseases (10) · Neoplasms by Site (10) · Multiple Endocrine Neoplasia (9) · Pathological Conditions, Signs and Symptoms (7) · Congenital Abnormalities (6) · Hamartoma (6) · Heredodegenerative Disorders, Nervous System (6) · Malformations of Cortical Development (6) · Malformations of Cortical Development, Group I (6)
Cannabidiol (2) · Everolimus (2) · Alpelisib (1) · Anti-Bacterial Agents (1) · Diet (1) · Doxycycline (1) · Dutasteride (1) · Exercise (1) · Fulvestrant (1) · Growth Hormone (1) · Lansoprazole (1) · Nutrition Assessment (1) · Vigabatrin (1) · Vitamin D (1) · candesartan (1)
Changi General Hospital (3) · Novartis Pharmaceuticals (3) · Jazz Pharmaceuticals (2) · Assistance Publique - Hôpitaux de Paris (1) · Charles Mel Wilcox, MD (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · McGill University (1) · Third Military Medical University (1) · Universidade Federal do Rio de Janeiro (1) · University of Nottingham (1) · University of Pennsylvania (1)
United States (4) · Singapore (3) · Canada (2) · China (2) · United Kingdom (2) · Brazil (1) · France (1) · India (1) · Poland (1) · Taiwan (1)
C. Mel Wilcox, M.D. (1) · Hope A Weiler, PhD, RD (1) · Joan J Khoo, MRCP (1) · Joan Khoo, MBBS,MRCP (1) · Joan Khoo, MRCP (1) · John Pollard, MD (1) · Louis Bernard, PU-PH (1) · Shalender Bhasin, MD (1) · Simon R Johnson, DM FRCP (1) · Zeng Chunyu, Doctor (1)
PMID 15645403, PMID 17767471, PMID 18507843, PMID 19581810, PMID 21073392, PMID 21193359, PMID 22396515, PMID 23635309, PMID 24382963, PMID 25468170, PMID 25984880, PMID 26201019, PMID 26438497, PMID 26871769, PMID 29280355, PMID 42435131
2023 (1), R01HD043348 (1)