3 active not recruiting, 3 completed, 2 recruiting, 1 terminated. 9 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Active not recruiting 3, Completed 3, Recruiting 2, Terminated 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Myeloid Neoplasm: new trials by email Literature Review of Myeloid Neoplasm trials Research Report on Myeloid Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies Decitabine, Filgrastim - Acute Myeloid Leukemia, Myelodysplastic Syndromes | Phase 2 | Active not recruiting | Franziska Wachter | 29 | 2023-04-19 | 2026-08-20 |
| Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms CPX-351, MHA, Allogeneic Hematopoietic Stem Cell Transplantation - Myeloid Neoplasm | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 25 | 2023-01-17 | 2026-10-15 |
| Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms Cladribine, Cytarabine, Mitoxantrone - Acute Biphenotypic Leukemia, Acute Myeloid Leukemia | Phase 1 / Phase 2 | Recruiting | University of Washington | 62 | 2022-02-04 | 2026-04-17 |
| Two Step Haplo With Radiation Conditioning Fludarabine, Total-Body Irradiation, Donor Lymphocyte Infusion - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | Thomas Jefferson University | 63 | 2021-10-25 | 2025-10-30 |
| CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease Allogeneic Hematopoietic Stem Cell Transplantation, Liposome-encapsulated Daunorubicin-Cytarabine - Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2 | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 1 | 2021-08-09 | 2024-05-23 |
| CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients Liposome-encapsulated Daunorubicin-Cytarabine, Cladribine, Cytarabine - Acute Myeloid Leukemia, Myeloid Neoplasm | Phase 2 | Completed | Fred Hutchinson Cancer Center | 60 | 2020-05-27 | 2026-06-29 |
| Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Azacitidine, Pevonedistat, Venetoclax - Acute Myeloid Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Phase 1 / Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 40 | 2019-02-27 | 2026-07-16 |
| Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm Cladribine, Cytarabine, Granulocyte Colony-Stimulating Factor - Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia | Phase 2 | Completed | University of Washington | 50 | 2016-12-30 | 2022-03-08 |
| Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms Cladribine, Cyclosporine, Cytarabine - Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Chronic Myelomonocytic Leukemia-2 | Phase 2 | Completed | University of Washington | 30 | 2016-09-22 | 2021-11-08 |
Leukemia, Myeloid, Acute (9) · Myelodysplastic Syndromes (5) · Leukemia, Biphenotypic, Acute (2) · Leukemia, Monocytic, Acute (2) · Leukemia, Myelomonocytic, Chronic (2) · Polycythemia Vera (2) · Primary Myelofibrosis (2) · Thrombocythemia, Essential (2) · Anemia, Aplastic (1) · Congenital Bone Marrow Failure Syndromes (1) · Hodgkin Disease (1) · Hypereosinophilic Syndrome (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (1)
Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Leukemia (9) · Leukemia, Myeloid (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Bone Marrow Diseases (5) · Immune System Diseases (3) · Immunoproliferative Disorders (3) · Leukemia, Lymphoid (3) · Lymphatic Diseases (3) · Lymphoproliferative Disorders (3) · Myelodysplastic-Myeloproliferative Diseases (3) · Blood Coagulation Disorders (2) · Blood Platelet Disorders (2)
Cytarabine (6) · Cladribine (4) · Mitoxantrone (4) · CPX-351 (3) · Daunorubicin (3) · Granulocyte Colony-Stimulating Factor (3) · Stem Cell Transplantation (3) · Filgrastim (2) · Injections (2) · Liposomes (2) · Melphalan (2) · Mycophenolic Acid (2) · Whole-Body Irradiation (2) · fludarabine phosphate (2) · pegylated granulocyte colony-stimulating factor (2)
University of Washington (3) · Fred Hutchinson Cancer Center (2) · Franziska Wachter (1) · M.D. Anderson Cancer Center (1) · St. Jude Children's Research Hospital (1) · Thomas Jefferson University (1)
United States (9)
Anna Halpern (1) · Filippo Milano (1) · Franziska Wachter, MD (1) · Marcin Wlodarski, MD, PhD (1) · Mary-Beth M. Percival (1) · Mary-Elizabeth Percival (1) · Nicholas Short (1) · Raul C. Ribeiro, MD (1) · Roland Walter (1) · Usama Gergis, MD (1)
P30CA015704 (2)