4 completed, 1 recruiting. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Malignant Brain Tumor: new trials by email Literature Review of Malignant Brain Tumor trials Research Report on Malignant Brain Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients SonoCloud® (9 transducers) - Malignant Brain Tumor, Malignant Glioma | Phase 1 | Recruiting | Assistance Publique - Hôpitaux de Paris | 24 | 2023-02-06 | 2026-05-06 |
| Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors Magrolimab - Brain Cancer, Malignant Brain Tumor | Phase 1 | Completed | University of California, San Francisco | 13 | 2022-04-22 | 2025-07-09 |
| Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors Indoximod, Temozolomide, Conformal Radiation - Glioblastoma Multiforme, Glioma | Phase 1 | Completed | NewLink Genetics Corporation | 81 | 2015-10-01 | 2020-06-04 |
| Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors Indoximod, Temozolomide, Bevacizumab - Glioblastoma Multiforme, Glioma | Phase 1 / Phase 2 | Completed | NewLink Genetics Corporation | 160 | 2014-03-01 | 2024-03-27 |
| Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma Tarceva (Erlotinib Hydrochloride) - Malignant Brain Tumor, Brain Stem Glioma, | Phase 1 | Completed | Gustave Roussy, Cancer Campus, Grand Paris | 48 | 2005-06-01 | 2009-08-07 |
Brain Neoplasms (5) · Glioma (3) · Glioblastoma (2) · Gliosarcoma (2) · Diffuse Intrinsic Pontine Glioma (1) · Ependymoma (1) · Medulloblastoma (1) · Neoplasms, Germ Cell and Embryonal (1)
Brain Diseases (5) · Central Nervous System Diseases (5) · Central Nervous System Neoplasms (5) · Neoplasms (5) · Neoplasms by Site (5) · Nervous System Diseases (5) · Nervous System Neoplasms (5) · Neoplasms by Histologic Type (3) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Nerve Tissue (3) · Neoplasms, Neuroepithelial (3) · Neuroectodermal Tumors (3) · Astrocytoma (2) · Neoplasms, Germ Cell and Embryonal (2) · Brain Stem Neoplasms (1)
1-methyltryptophan (2) · Temozolomide (2) · Bevacizumab (1) · Cyclophosphamide (1) · Erlotinib Hydrochloride (1) · Etoposide (1) · Radiosurgery (1) · Spermine Synthase (1) · magrolimab (1)
NewLink Genetics Corporation (2) · Assistance Publique - Hôpitaux de Paris (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · University of California, San Francisco (1)
United States (3) · France (2)
Gene Kennedy, MD (1) · Howard Colman, MD PhD FAAN (1) · Nicholas Whipple, MD, MPH (1) · Sabine Mueller, MD, PhD (1) · Samuel Cheshier, MD, PhD (1) · Vassal Gilles, Pr. (1)