3 completed, 3 not yet recruiting, 3 recruiting. 3 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Lower Respiratory Tract Infection (LRTI): new trials by email Literature Review of Lower Respiratory Tract Infection (LRTI) trials Research Report on Lower Respiratory Tract Infection (LRTI)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevent Wheeze Trial Dexamethasone 0.6 mg/kilogram body weight single dose, Placebo - Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing | Phase 4 | Not yet recruiting | Norwegian University of Science and Technology | 486 | 2027-02-01 | 2026-10-05 |
| Quality of Life After Lower Respiratory Tract Infection Lower Respiratory Tract Infection (LRTI), Chest Infection | Not yet recruiting | University of Nottingham | 200 | 2026-09-01 | 2026-09-30 | |
| Optimising Antibiotic Use for Paediatric Lower Respiratory Tract Infections in Africa CRP- and PREPARE-guided Antibiotic Prescription - Lower Respiratory Tract Infection (LRTI), Pneumonia | Not applicable | Recruiting | University of Witwatersrand, South Africa | 400 | 2026-05-27 | 2026-09-25 |
| Post Authorization Efficacy and Safety Study (PAES) to Confirm and Collect More Clinical Data of Buccalin® Tablets In the Prophylaxis of Recurrent Lower Respiratory Tract Infections (RLRTIs). BUCCALIN®, Placebo - Respiratory Infection, Lower Respiratory Tract Infection (LRTI) | Phase 4 | Recruiting | Laboratorio Farmaceutico SIT srl | 240 | 2025-10-21 | 2025-12-10 |
| Procalcitonin Aided Antimicrobial Therapy vs Standard of Care Procalcitonin-guided antibiotic management, Standard of care - Lower Respiratory Tract Infection (LRTI) | Not applicable | Not yet recruiting | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | 108 | 2025-06-01 | 2025-05-07 |
| Novel Exhaled Breath Aerosol Collection Devices in Patients With Lower Respiratory Tract Infection - a Performance and Acceptability Study Sputum collection for molecular analysis, Breath and cough collection for molecular analysis - Pneumonia, Lower Respiratory Tract Infection (LRTI) | Completed | Avelo AG | 23 | 2024-11-13 | 2025-08-08 | |
| Respiratory Infections in Young Children Respiratory Tract Infections (RTI), Lower Respiratory Tract Infection (LRTI) | Recruiting | Eduardo Lopez -Medina | 1088 | 2024-05-02 | 2025-11-25 | |
| Procalcitonin Antibiotic Consensus Trial (ProACT) Procalcitonin level, Results of procalcitonin (PCT) level to treating clinician, Provide procalcitonin guideline to treating clinician - Lower Respiratory Tract Infection (LRTI) | Not applicable | Completed | University of Pittsburgh | 1664 | 2014-11-03 | 2019-01-15 |
| An Observational Study of Cough / Lower Respiratory Tract Infection (LRTI) in Primary Care Cough, Lower Respiratory Tract Infection (LRTI) | Completed | Cardiff University | 3402 | 2006-09-01 | 2008-05-20 |
Pneumonia (3) · Respiratory Tract Infections (3) · Asthma (1) · Bronchiolitis (1) · Bronchitis (1) · Bronchopneumonia (1) · Communicable Diseases (1) · Community-Acquired Pneumonia (1) · Cough (1) · Infections (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Sounds (1) · Virus Diseases (1)
Respiratory Tract Diseases (8) · Infections (5) · Lung Diseases (5) · Pathological Conditions, Signs and Symptoms (4) · Bronchial Diseases (3) · Lung Diseases, Obstructive (3) · Respiratory Tract Infections (3) · Disease Attributes (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Signs and Symptoms, Respiratory (2) · Bronchitis (1) · Chronic Disease (1) · Community-Acquired Infections (1) · Hypersensitivity (1)
Dexamethasone (1) · Procalcitonin (1) · Standard of Care (1) · buccalin (1)
Avelo AG (1) · Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria (1) · Cardiff University (1) · Eduardo Lopez -Medina (1) · Laboratorio Farmaceutico SIT srl (1) · Norwegian University of Science and Technology (1) · University of Nottingham (1) · University of Pittsburgh (1) · University of Witwatersrand, South Africa (1)
Italy (2) · South Africa (2) · United Kingdom (2) · Colombia (1) · Nepal (1) · North Macedonia (1) · Panama (1) · Switzerland (1) · United States (1)
Chris A Rees, PhD (1) · Christopher C Butler, FRCGP CCH MD (1) · David P Moore, PhD (1) · David T Huang, MD MPH (1) · Eduardo Lopez-Medina, MD, MSc (1) · Kari R. Risnes, PhD (1) · Lucy N Wilson, MBBCh, MMED, FCPaed (1) · Ziyaad Dangor, PhD (1)
PMID 19549995, PMID 20032009, PMID 21406512, PMID 21794112, PMID 28851296, PMID 29781385, PMID 36658543, PMID 42721424
R01GM101197 (1)