21 completed, 6 unknown, 3 recruiting, 3 terminated. 20 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 12, Unknown 3, Terminated 2, Withdrawn 2, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Procalcitonin: new trials by email Literature Review of Procalcitonin trials Research Report on Procalcitonin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients Interleukin 6 - Burns, Sepsis | Not applicable | Recruiting | Ain Shams University | 70 | 2025-01-10 | 2025-04-08 |
| Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children procalcitonin - Non-cystic Fibrosis Bronchiectasis | Unknown | Assiut University | 30 | 2024-07-01 | 2024-04-17 | |
| Role of PCO2 Gap as Predictor of Clinical Outcome in ICU Septic Patients measurement of serum lactate and procalcitonin and PCO2 gap - Sepsis | Unknown | Ain Shams University | 80 | 2024-02-01 | 2024-02-13 | |
| Early Detection of At-risk Septic Patients Measuring tissue oxygenation, Procalcitonin, Mid-regional proadrenomedullin - Sepsis | Recruiting | University Hospital Southampton NHS Foundation Trust | 60 | 2024-01-12 | 2024-12-02 | |
| Use of Procalcitonin, a Blood Test to Guide Antibiotic Therapy for Sepsis in Adults Procalcitonin measurement - Sepsis | Phase 3 | Completed | University of Oxford | 532 | 2023-07-26 | 2026-09-22 |
| PROcalcitonin and Presepsin-guided Decision for Antibiotic Prophylaxis of EOS Procalcitonin/Presepsin guided antibiotic prophylaxis for EOS, Antibiotic prophylaxis for EOS - Early-Onset Neonatal Sepsis | Not applicable | Unknown | University of Florence | 266 | 2023-04-01 | 2023-04-03 |
| Comparison of Procalcitonin Level in Normal Population and in Chronic Kidney Disease Patients Who Don't Have Infection procalcitonin - Chronic Kidney Disease Patients Who Don't Have Infection | Not applicable | Unknown | Sohag University | 50 | 2022-11-01 | 2022-10-19 |
| Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection Data collection: Participant characteristics (Illness course, complications of primary EBV infection and provided treatments), Data collection: blood samples (analysed for EBV serology, auto-antibody-testing/biobanking, RNA expression analyses, procalcitonin), Data collection: Patient reported outcome (Fatigue questionnaires) - Epstein-Barr Virus (EBV) Infection | Recruiting | University Hospital, Basel, Switzerland | 80 | 2021-10-15 | 2025-02-25 | |
| PCT-guided Treatment Regarding Antibiotic Use for Acute COPD Exacerbations Procalcitonin, Physician's decision - COPD Exacerbation, COPD | Not applicable | Completed | Erasmus Medical Center | 693 | 2021-08-10 | 2026-08-13 |
| Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. Intervention: Combined use of a respiratory broad panel multiplex PCR and procalcitonin, Control: usual antibiotic treatment - Acute Chest Syndrome, Sickle Cell Disease | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 72 | 2020-06-02 | 2025-03-24 |
| PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT procalcitonin - Pneumonia, Bacterial | Not applicable | Completed | Massachusetts General Hospital | 700 | 2020-05-28 | 2025-03-20 |
| Use of a Respiratory Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Patients With Severe Confirmed COVID-19 Pneumonia Combined use of a respiratory broad panel multiplex PCR and procalcitonin, Usual antibiotic treatment - Covid19, Pneumonia | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 194 | 2020-04-20 | 2021-08-03 |
| The Procalcitonin Guided Antibiotics in Respiratory Infections in General Practice Procalcitonin - Acute Respiratory Tract Infection | Not applicable | Withdrawn | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 2020-02-27 | 2023-03-27 | |
| Role and Value of Inflammatory Markers in Brain Tumors : A Case Controlled Study Procalcitonin - Brain Tumor | Completed | Universitas Sumatera Utara | 35 | 2020-01-01 | 2020-11-18 | |
| An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care UltraPro, Procalcitonin, Blood sampling - Lower Resp Tract Infection | Not applicable | Completed | Centre Hospitalier Universitaire Vaudois | 469 | 2018-09-01 | 2020-07-17 |
| HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study HostDx Sepsis - Respiratory Tract Infections, Urinary Tract Infections | Completed | Inflammatix | 585 | 2018-07-23 | 2021-12-03 | |
| Evaluation of Procalcitonin (PCT) as a Marker of Infection Post Living Donated Liver Transplant procalcitonin - Liver Transplant Infection | Completed | National Hepatology & Tropical Medicine Research Institute | 60 | 2018-03-15 | 2021-03-19 | |
| Evaluation of the Roche Liat Flu/RSV Assay for Management of Influenza in the Emergency Department Procalcitonin, Pharmacist-Led Education - Influenza, Human | Not applicable | Completed | University of California, Davis | 200 | 2018-03-06 | 2023-10-17 |
| Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD procalcitonin - Acute Exacerbation Copd | Not applicable | Unknown | University Hospital, Mahdia | 100 | 2017-10-05 | 2019-05-13 |
| Predicting the Severity of Post-cesarean Wound Infections Using Serum Procalcitonin Levels procalcitonin level - Wound Infection, Cesarean Wound Disruption | Completed | Kanuni Sultan Suleyman Training and Research Hospital | 90 | 2017-05-02 | 2017-10-24 |
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Sepsis (8) · Infections (3) · Pneumonia (3) · Bacterial Infections (2) · Disease (2) · Intraabdominal Infections (2) · Premature Birth (2) · Pulmonary Disease, Chronic Obstructive (2) · Acute Chest Syndrome (1) · Anemia, Sickle Cell (1) · Brain Diseases (1) · Brain Neoplasms (1) · Bronchiectasis (1) · Bronchitis (1) · Burns (1)
Ain Shams University (2) · Assistance Publique - Hôpitaux de Paris (2) · Erasmus Medical Center (2) · Ain Shams Maternity Hospital (1) · Assiut University (1) · Bangkok Metropolitan Administration Medical College and Vajira Hospital (1) · Brahms AG (1) · Brahms France (1) · CAMC Health System (1) · Centre Hospitalier Departemental Vendee (1) · Centre Hospitalier Universitaire Vaudois (1) · Centre Hospitalier Universitaire, Amiens (1) · Charite University, Berlin, Germany (1) · Chronic Obstructive Pulmonary Disease Trial Network, Denmark (1) · Federal University of Minas Gerais (1)
United States (6) · France (5) · Egypt (4) · Netherlands (4) · Brazil (2) · Denmark (2) · Germany (2) · Spain (2) · Switzerland (2) · Bangladesh (1) · Greece (1) · Indonesia (1) · Norway (1) · Thailand (1) · Tunisia (1)
Ahilanandan Dushianthan, PhD (1) · Ahmed H Elsayed, M.B.B.CH (1) · Alan Maisel, MD (1) · Alev Atis, MD,ObGyn (1) · Andreas Meisel, MD (1) · Arjen Dondorp, Professor (1) · David T Huang, MD MPH (1) · Djillali Annane, Professor (1) · Douglas W Haden, MD (1) · Henrique NS Bittencourt, PhD (1) · James N Ward, BM (1) · Larissa S May, MD (1)
PMID 10519716, PMID 10835436, PMID 10959733, PMID 11014424, PMID 11229684, PMID 12147798, PMID 12601102, PMID 1357073, PMID 14987884, PMID 17431204, PMID 17478736, PMID 18379262, PMID 18650914, PMID 19049549, PMID 19493352, PMID 19738090, PMID 21283001, PMID 21720792, PMID 21920453, PMID 22925000, PMID 23780645, PMID 24202395, PMID 24281089, PMID 24320627, PMID 24793958, PMID 25666772, PMID 27384242, PMID 27397086, PMID 27592364, PMID 27746396, PMID 28092374, PMID 28105073, PMID 28484421, PMID 28851296, PMID 29202730, PMID 29514604, PMID 29781385, PMID 29804483, PMID 31387559, PMID 32098866, PMID 33280547, PMID 34548312, PMID 35279069, PMID 36658543, PMID 37169498, PMID 39995490, PMID 42724645, PMID 7482646, PMID 8094770, PMID 8280464
R01GM101197 (1)