2 active not recruiting, 2 recruiting, 1 completed, 1 no longer available. 4 Phase 2, 2 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Terminated 1 |
| Not applicable | 2 | Recruiting 1, Withdrawn 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Locally Advanced Pancreatic Carcinoma: new trials by email Literature Review of Locally Advanced Pancreatic Carcinoma trials Research Report on Locally Advanced Pancreatic Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial Tumor collection via biopsy, Blood collection, Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI) - Locally Advanced Cervical Carcinoma, Locally Advanced Cervical Cancer | Not applicable | Recruiting | Washington University School of Medicine | 60 | 2024-01-11 | 2026-08-17 |
| Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Carcinoma, Stage II Pancreatic Cancer AJCC v8 | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 18 | 2023-05-22 | 2026-07-10 |
| Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors BET Bromodomain Inhibitor ZEN-3694, Computed Tomography, Core Biopsy - Advanced Malignant Solid Neoplasm, Locally Advanced Pancreatic Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 49 | 2022-11-16 | 2026-07-15 |
| Quality of Life With Nutritional Supplementation in Patients With Locally Advanced/Metastatic Pancreatic Cancer. ARACOMPLEX®, placebo - Quality of Life, Locally Advanced Pancreatic Carcinoma | Not applicable | Withdrawn | Fundacion para la Excelencia y la Calidad de la Oncologia | 2022-06-29 | 2026-02-11 | |
| Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations Biopsy Procedure, Biospecimen Collection, Computed Tomography - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 29 | 2021-04-26 | 2026-08-19 |
| Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation Binimetinib, Encorafenib - Locally Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma | Phase 2 | Terminated | Academic and Community Cancer Research United | 6 | 2020-11-16 | 2024-05-06 |
| Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study Endoscopic Ultrasound, Fluorescence Imaging, Photodynamic Therapy - Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Carcinoma | Phase 2 | Completed | Mayo Clinic | 13 | 2017-05-31 | 2025-07-30 |
| Expanded Access to NanoPac NanoPac (sterile nanoparticulate paclitaxel) Powder for Suspension - Locally Advanced Pancreatic Carcinoma, Prostate Cancer | No longer available | NanOlogy, LLC | 2026-01-23 |
Pancreatic Neoplasms (7) · Prostatic Neoplasms (2) · Breast Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1) · Stomach Neoplasms (1) · Uterine Cervical Neoplasms (1)
Neoplasms (8) · Neoplasms by Site (8) · Digestive System Diseases (7) · Digestive System Neoplasms (7) · Endocrine Gland Neoplasms (7) · Endocrine System Diseases (7) · Pancreatic Diseases (7) · Genital Diseases (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases, Female (2) · Genital Diseases, Male (2) · Genital Neoplasms, Female (2)
Biopsy (2) · Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · 1-phenyl-3,3-dimethyltriazene (1) · Biopsy, Large-Core Needle (1) · Biopsy, Needle (1) · Blood Specimen Collection (1) · Disulfides (1) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Immunoglobulin G (1) · Magnetic Resonance Imaging (1) · Optical Imaging (1) · Paclitaxel (1) · Photochemotherapy (1) · Phototherapy (1)
National Cancer Institute (NCI) (3) · Academic and Community Cancer Research United (1) · Fundacion para la Excelencia y la Calidad de la Oncologia (1) · Mayo Clinic (1) · NanOlogy, LLC (1) · Washington University School of Medicine (1)
United States (6) · Canada (1)
A P Chen (1) · Andrew E Hendifar (1) · Michael Waters, M.D., Ph.D. (1) · Patricia M LoRusso (1) · Sergio Sandiego, Doctor (1) · Vaibhav Sahai (1) · Vinay Chandrasekhara, M.D. (1)
PMID 33647286, PMID 34261044, PMID 39863139
P01CA084203 (1), P30CA015083 (1), P30CA046592 (1), U54CA274318 (1), UM1CA186689 (1)