14 completed, 5 recruiting, 5 terminated, 3 unknown. 13 Phase 2, 4 Not applicable, 4 Phase 1, 4 Phase 3.
Follow Lipomatosis: new trials by email Literature Review of Lipomatosis trials Research Report on Lipomatosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease Lipomas CBL-514 injection, 0.9% Sodium chloride - Dercum's Disease | Phase 2 | Completed | Caliway Biopharmaceuticals Co., Ltd. | 19 | 2024-11-27 | 2026-09-22 |
| A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections Mavorixafor, Placebo - Neutropenia | Phase 3 | Recruiting | X4 Pharmaceuticals | 176 | 2024-06-06 | 2026-08-06 |
| Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform Shwachman-Diamond Syndrome, SDS | Recruiting | Shwachman-Diamond Syndrome Alliance Inc | 8000 | 2024-02-07 | 2025-05-31 | |
| Evaluation of Safety and Efficiency of Metreleptin Treatment for Patients With Multiple Symmetric Lipomatosis (MSL) Metreleptin - Lipomatosis, Multiple Symmetrical | Phase 2 | Active not recruiting | University of Michigan | 4 | 2023-08-01 | 2025-06-12 |
| A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas 10 mg CBL-514 per injection, 15 mg CBL-514 per injection - Dercum's Disease | Phase 2 | Completed | Caliway Biopharmaceuticals Co., Ltd. | 12 | 2022-10-03 | 2023-04-20 |
| Baby Detect : Genomic Newborn Screening Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1 | Completed | Centre Hospitalier Universitaire de Liege | 6824 | 2022-09-01 | 2025-08-12 | |
| Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904) Treosulfan, Fludarabine Phosphate, Tacrolimus - Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2022-04-19 | 2026-03-09 |
| Prospective Study on the Consequences of Weight Loss After Bariatric Surgery on Obese Patients' Spine. Full Spine Radiography, Lumbar spine MRI - Low Back Pain in Obese Patients After Important Weight Loss | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 80 | 2021-06-03 | 2025-09-15 |
| Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone, Placebo - Symmetric Lipomatoses, Multiple | Phase 3 | Unknown | Erasmus Medical Center | 1 | 2021-06-01 | 2021-03-29 |
| Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis. Spinal Cord Stimulator - Lipomatosis, Low Back Pain | Completed | University Hospitals Cleveland Medical Center | 3 | 2020-09-22 | 2026-02-03 | |
| Diabetes/ Endocrine Surveillance in SDS Oral Glucose Tolerance Test, Modified Oral Glucose Tolerance Test, Modified Mixed Meal Tolerance Test - Shwachman-Diamond Syndrome | Terminated | Washington University School of Medicine | 11 | 2020-01-10 | 2024-08-19 | |
| Treatment of Women With Lipedema Involving Substantial Fat Knee of Women and Men With Nodular Dercum's Disease RZL-012 - Lipedema, Dercum Disease | Phase 2 | Completed | Raziel Therapeutics Ltd. | 12 | 2018-06-28 | 2024-02-08 |
| Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer Cyclophosphamide, Fludarabine Phosphate, Laboratory Biomarker Analysis - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Leukemia in Remission | Phase 2 | Terminated | Roswell Park Cancer Institute | 31 | 2017-12-07 | 2025-07-04 |
| Insight Into Subcutaneous Adipose Tissue Disorders Lipedema, Dercum's Disease | Unknown | University of Arizona | 500 | 2016-06-01 | 2017-09-15 | |
| Shwachman Diamond Syndrome Registry and Study Shwachman-Diamond Syndrome, Shwachman-Diamond Syndrome-Like | Recruiting | Boston Children's Hospital | 5000 | 2016-01-19 | 2026-04-06 | |
| Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content Consumed Alone. Sandwich biscuit high in SDS, Co-extruded cereal low in SDS - Metabolic Disorder; Carbohydrate, Absorption, Intestine | Not applicable | Completed | Mondelēz International, Inc. | 20 | 2015-09-01 | 2017-09-14 |
| Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases BPX-501 and Rimiducid - Primary Immune Deficiency Disorders, Hemophagocytic Lymphohistiocytosis | Phase 1 | Terminated | Bellicum Pharmaceuticals | 1 | 2015-02-01 | 2024-03-25 |
| Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies Reduced Toxicity Ablative Regimen, Reduced Intensity Preparative Regimen, Myeloablative Preparative Regimen - Sickle Cell Disease, Transfusion Dependent Alpha- or Beta- Thalassemia | Not applicable | Terminated | Masonic Cancer Center, University of Minnesota | 38 | 2014-09-02 | 2025-03-03 |
| Bone Marrow Transplant With Abatacept for Non-Malignant Diseases Abatacept - Hurler Syndrome, Fanconi Anemia | Phase 1 | Completed | Emory University | 10 | 2014-01-01 | 2019-12-26 |
| CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant CliniMACS CD34+ Reagent System, Thiotepa, Cyclophosphamide - Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML) | Phase 1 / Phase 2 | Unknown | Diane George | 14 | 2013-06-03 | 2024-06-04 |
Showing 20 of 30. Sign in to see all of them.
Shwachman-Diamond Syndrome (21) · Anemia, Diamond-Blackfan (14) · Neutropenia, Severe Congenital, Autosomal Recessive 3 (11) · Anemia, Sickle Cell (10) · Anemia, Aplastic (9) · Dyskeratosis Congenita (7) · Fanconi Anemia (7) · Bone Marrow Failure Disorders (6) · Lymphohistiocytosis, Hemophagocytic (6) · Wiskott-Aldrich Syndrome (6) · Adiposis Dolorosa (5) · Granulomatous Disease, Chronic (5) · Lipedema (5) · Primary Immunodeficiency Diseases (5) · Thalassemia (5)
Nutritional and Metabolic Diseases (30) · Lipid Metabolism Disorders (28) · Metabolic Diseases (26) · Hemic and Lymphatic Diseases (22) · Bone Marrow Diseases (21) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (21) · Digestive System Diseases (21) · Lipid Metabolism, Inborn Errors (21) · Pancreatic Diseases (21) · Hematologic Diseases (20) · Exocrine Pancreatic Insufficiency (19) · Genetic Diseases, Inborn (19) · Congenital Bone Marrow Failure Syndromes (17) · Skin and Connective Tissue Diseases (17)
fludarabine phosphate (7) · Antilymphocyte Serum (4) · Peripheral Blood Stem Cell Transplantation (4) · Tacrolimus (4) · Whole-Body Irradiation (4) · Busulfan (3) · Cyclophosphamide (3) · Methotrexate (3) · Alemtuzumab (2) · Bone Marrow Transplantation (2) · Melphalan (2) · Mycophenolic Acid (2) · fludarabine (2) · merphos (2) · thymoglobulin (2)
Masonic Cancer Center, University of Minnesota (3) · Caliway Biopharmaceuticals Co., Ltd. (2) · Diane George (2) · Emory University (2) · Fred Hutchinson Cancer Center (2) · Roswell Park Cancer Institute (2) · Assistance Publique - Hôpitaux de Paris (1) · Bellicum Pharmaceuticals (1) · Boston Children's Hospital (1) · Centre Hospitalier Universitaire de Liege (1) · Erasmus Medical Center (1) · Mondelēz International, Inc. (1) · National Cancer Institute (NCI) (1) · National Center for Research Resources (NCRR) (1) · Raziel Therapeutics Ltd. (1)
United States (24) · Belgium (3) · Australia (2) · Czechia (2) · France (2) · Germany (2) · Italy (2) · Netherlands (2) · Spain (2) · Switzerland (2) · Argentina (1) · Austria (1) · Canada (1) · Colombia (1) · Denmark (1)
Diane George, MD (2) · Angela Smith, MD (1) · Anne Sheu (1) · Ashish Gupta, MBBS, MPH (1) · David A. Williams (1) · Elif Oral (1) · Eva M Sevick, PhD (1) · Garry Tobin, MD (1) · George Chen (1) · Jennie Brand Miller (1) · John Horan, MD (1) · John T Horan, MD (1) · Karen L Herbst, PhD, MD (1)
PMID 24786393, PMID 25304614, PMID 25405500, PMID 25425683, PMID 25963299, PMID 26095669, PMID 28280134, PMID 28623992, PMID 31836590, PMID 32790018, PMID 33786515, PMID 33810313, PMID 34162668, PMID 34852175, PMID 35322185, PMID 35360980, PMID 37354000, PMID 39279436, PMID 40097137, PMID 40762130
2023 (1), P30CA015704 (1), R01CA128919 (1), R01HL092923 (1), U10HL069294 (1)