3 completed, 1 enrolling by invitation, 1 unknown. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
Follow Adiposis Dolorosa: new trials by email Literature Review of Adiposis Dolorosa trials Research Report on Adiposis Dolorosa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease Lipomas CBL-514 injection, 0.9% Sodium chloride - Dercum's Disease | Phase 2 | Completed | Caliway Biopharmaceuticals Co., Ltd. | 19 | 2024-11-27 | 2026-09-22 |
| A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas 10 mg CBL-514 per injection, 15 mg CBL-514 per injection - Dercum's Disease | Phase 2 | Completed | Caliway Biopharmaceuticals Co., Ltd. | 12 | 2022-10-03 | 2023-04-20 |
| Treatment of Women With Lipedema Involving Substantial Fat Knee of Women and Men With Nodular Dercum's Disease RZL-012 - Lipedema, Dercum Disease | Phase 2 | Completed | Raziel Therapeutics Ltd. | 12 | 2018-06-28 | 2024-02-08 |
| Insight Into Subcutaneous Adipose Tissue Disorders Lipedema, Dercum's Disease | Unknown | University of Arizona | 500 | 2016-06-01 | 2017-09-15 | |
| Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders NIRFLI with ICG - Lymphedema, Lymphatic Disorders | Enrolling by invitation | The University of Texas Health Science Center, Houston | 283 | 2009-01-01 | 2026-03-10 |
Lipedema (5) · Connective Tissue Diseases (2) · Lipid Metabolism Disorders (2) · Lipomatosis (2) · Skin Diseases (2) · Familial Multiple Lipomatosis (1) · Lipomatosis, Multiple Symmetrical (1) · Lymphatic Diseases (1) · Lymphedema (1) · Metabolic Diseases (1) · Vascular Malformations (1)
Nutritional and Metabolic Diseases (5) · Skin and Connective Tissue Diseases (5) · Metabolic Diseases (4) · Connective Tissue Diseases (3) · Lipid Metabolism Disorders (3) · Lipomatosis (3) · Skin Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Congenital Abnormalities (1) · Genetic Diseases, Inborn (1) · Hemic and Lymphatic Diseases (1)
Indocyanine Green (1) · RZL-012 (1) · Sodium Chloride (1)
Caliway Biopharmaceuticals Co., Ltd. (2) · Raziel Therapeutics Ltd. (1) · The University of Texas Health Science Center, Houston (1) · University of Arizona (1)
United States (5)
Anne Sheu (1) · Eva M Sevick, PhD (1) · Karen L Herbst, PhD, MD (1)
PMID 28623992, PMID 33786515, PMID 40097137
R01CA128919 (1), R01HL092923 (1)