Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Lactate Elevation: Clinical Trials

4 trials for Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Lactate Elevation, newest first

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3 recruiting, 1 completed. 1 Not applicable.

By phase and status

PhaseTrialsStatus
Not applicable1Recruiting 1

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TrialPhaseStatusSponsorEnrollmentStartUpdated
Home Exercise for Individuals With Neurodegenerative Disease
Home exercise - Neurodegenerative Diseases, Leukodystrophy
Not applicableRecruitingHugo W. Moser Research Institute at Kennedy Krieger, Inc.302023-02-132026-09-16
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)
Leukoencephalopathies, LBSL
RecruitingHugo W. Moser Research Institute at Kennedy Krieger, Inc.1002018-04-012024-07-03
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophy, White Matter Disease
CompletedChildren's Hospital of Philadelphia2362017-01-062025-11-10
The Myelin Disorders Biorepository Project
Leukodystrophy, White Matter Disease
RecruitingChildren's Hospital of Philadelphia120002016-12-082025-10-23

Narrower conditions

Adrenoleukodystrophy (3)  ·  Leukoencephalopathies (3)  ·  Aicardi-Goutieres syndrome (2)  ·  Alexander Disease (2)  ·  Alexanders leukodystrophy (2)  ·  Allan-Herndon-Dudley syndrome (2)  ·  Attention Deficit Disorder with Hyperactivity (2)  ·  CADASIL (2)  ·  Canavan Disease (2)  ·  Cerebellar Ataxia (2)  ·  Charcot-Marie-Tooth Disease (2)  ·  Cockayne Syndrome (2)  ·  Gangliosidoses (2)  ·  Gangliosidoses, GM2 (2)

Broader conditions

Brain Diseases (4)  ·  Central Nervous System Diseases (4)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4)  ·  Nervous System Diseases (4)  ·  Neurologic Manifestations (4)  ·  Pathological Conditions, Signs and Symptoms (4)  ·  Adrenal Gland Diseases (3)  ·  Adrenal Insufficiency (3)  ·  Brain Diseases, Metabolic (3)  ·  Brain Diseases, Metabolic, Inborn (3)  ·  Demyelinating Diseases (3)  ·  Endocrine System Diseases (3)  ·  Genetic Diseases, Inborn (3)  ·  Genetic Diseases, X-Linked (3)  ·  Hereditary Central Nervous System Demyelinating Diseases (3)

Sponsors

Children's Hospital of Philadelphia (2)  ·  Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (2)

Countries

United States (4)

Top investigators

Adeline Vanderver, MD (2)  ·  Amena S Fine, MD PhD (1)  ·  Jennifer Keller, PT (1)

Results publications

PMID 32342562, PMID 32749716

NIH funding

U01NS106845 (1), U54NS115052 (1)