128 completed, 27 terminated, 12 unknown, 4 withdrawn. 84 Phase 2, 58 Phase 1, 24 Phase 3, 5 Not applicable, 1 Early Phase 1.
Follow Leukemia, Erythroblastic, Acute: new trials by email Literature Review of Leukemia, Erythroblastic, Acute trials Research Report on Leukemia, Erythroblastic, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers Fludarabine, Cyclophosphamide, Thiotepa - Acute Erythroid Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 1 | 2022-10-06 | 2025-01-01 |
| Efficacy and Safety of HVA Regimens as Salvage Treatment in rrAML HVA Regimens as Salvage Treatment - Refractory Acute Myeloid Leukemia, Relapsed Acute Erythroid Leukemia | Phase 2 | Completed | Nanfang Hospital, Southern Medical University | 96 | 2020-05-27 | 2022-10-26 |
| A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia Volasertib, Idarubicin, Cytarabine - Leukemia, Myeloid, Acute, Leukemia, Monocytic, Acute | Phase 1 | Withdrawn | University of Alberta | 2016-11-01 | 2017-04-05 | |
| Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML metformin hydrochloride, cytarabine, laboratory biomarker analysis - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 | Terminated | Northwestern University | 2 | 2015-03-11 | 2019-01-31 |
| Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR 5-Azacytidine, Fludarabine, Melphalan - Leukemia, Erythroblastic, Acute, Myelodysplastic Syndromes | Phase 2 | Completed | Weill Medical College of Cornell University | 40 | 2015-02-13 | 2021-09-22 |
| MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia MEK inhibitor MEK162, idarubicin, cytarabine - Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a) | Phase 1 | Terminated | Bruno C. Medeiros | 1 | 2014-12-01 | 2017-12-06 |
| Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy eltrombopag olamine - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Basophilic Leukemia | Phase 2 | Completed | Case Comprehensive Cancer Center | 31 | 2014-08-14 | 2026-08-07 |
| Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia cytarabine, omacetaxine mepesuccinate, decitabine - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7) | Phase 2 | Terminated | Roswell Park Cancer Institute | 2 | 2014-07-01 | 2016-05-09 |
| Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Ixazomib - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 2 | Terminated | Steven E. Coutre | 4 | 2014-03-01 | 2019-04-05 |
| CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome liposomal cytarabine-daunorubicin CPX-351 - Adult Acute Erythroid Leukemia (M6), Adult Acute Megakaryoblastic Leukemia (M7) | Phase 2 | Completed | Rondeep Brar | 11 | 2014-02-03 | 2019-01-22 |
| Lenalidomide and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia lenalidomide, mitoxantrone hydrochloride, etoposide - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 | Terminated | Stanford University | 17 | 2014-02-01 | 2018-10-29 |
| AML Therapy With Irradiated Allogeneic Cells fludarabine phosphate, cytarabine, donor lymphocytes - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Not applicable | Terminated | Rutgers, The State University of New Jersey | 6 | 2014-02-01 | 2021-08-24 |
| Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay antitumor drug screening assay, chemotherapy, biological therapy - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Not applicable | Completed | University of Washington | 16 | 2013-08-02 | 2018-07-11 |
| Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies Aldesleukin, Allogeneic CD56-positive CD3-negative Natural Killer Cells, Allogeneic Hematopoietic Stem Cell Transplantation - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Erythroid Leukemia | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 63 | 2013-06-11 | 2023-11-07 |
| Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes pravastatin sodium, idarubicin, cytarabine - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Not applicable | Completed | Fred Hutchinson Cancer Center | 24 | 2013-05-01 | 2017-11-17 |
| Arsenic Trioxide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia arsenic trioxide, laboratory biomarker analysis - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 2 | Withdrawn | Stanford University | 2013-05-01 | 2018-05-21 | |
| Cytarabine With or Without SCH 900776 in Treating Adult Patients With Relapsed Acute Myeloid Leukemia Cytarabine, CHK1 Inhibitor SCH 900776, Laboratory Biomarker Analysis - Adult Acute Megakaryoblastic Leukemia, Adult Acute Monoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 32 | 2013-05-01 | 2016-09-01 |
| Lithium Carbonate and Tretinoin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia tretinoin, lithium carbonate, laboratory biomarker analysis - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a) | Phase 1 | Completed | Paolo Caimi, MD | 12 | 2013-04-30 | 2017-04-27 |
| Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Sirolimus, Idarubicin, Cytarabine - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a) | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 55 | 2013-03-15 | 2025-04-29 |
| Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia mitoxantrone hydrochloride, cytarabine, peripheral blood stem cell transplantation - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a) | Phase 1 | Terminated | University of Southern California | 10 | 2013-03-06 | 2018-03-30 |
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Leukemia, Myeloid, Acute (173) · Leukemia, Megakaryoblastic, Acute (166) · Leukemia, Monocytic, Acute (162) · Leukemia, Myelomonocytic, Acute (159) · Congenital Abnormalities (127) · Leukemia (96) · Leukemia, Basophilic, Acute (53) · Leukemia, Eosinophilic, Acute (53) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (36) · Myelodysplastic Syndromes (31) · Leukemia, Promyelocytic, Acute (29) · Blast Crisis (27) · Anemia, Refractory, with Excess of Blasts (24) · Leukemia, Myelomonocytic, Chronic (23)
Bone Marrow Diseases (175) · Hematologic Diseases (175) · Hemic and Lymphatic Diseases (175) · Leukemia, Myeloid (175) · Neoplasms by Histologic Type (175) · Neoplasms (174) · Myeloproliferative Disorders (158) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (127) · Leukemia (79) · Disease Attributes (46) · Pathologic Processes (46) · Pathological Conditions, Signs and Symptoms (46) · Chronic Disease (45) · Immune System Diseases (36) · Immunoproliferative Disorders (36)
Cytarabine (75) · Etoposide (31) · Daunorubicin (27) · Filgrastim (24) · Idarubicin (23) · Mitoxantrone (23) · Busulfan (22) · Cyclophosphamide (20) · Peripheral Blood Stem Cell Transplantation (20) · fludarabine phosphate (19) · Gemtuzumab (14) · Antilymphocyte Serum (11) · tipifarnib (11) · Clofarabine (10) · Cyclosporine (10)
National Cancer Institute (NCI) (43) · Fred Hutchinson Cancer Center (12) · SWOG Cancer Research Network (11) · Case Comprehensive Cancer Center (10) · European Organisation for Research and Treatment of Cancer - EORTC (8) · Roswell Park Cancer Institute (8) · Alliance for Clinical Trials in Oncology (6) · Eastern Cooperative Oncology Group (6) · ECOG-ACRIN Cancer Research Group (4) · Northwestern University (4) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (4) · Children's Oncology Group (3) · Memorial Sloan Kettering Cancer Center (3) · Rutgers, The State University of New Jersey (3) · Barbara Ann Karmanos Cancer Institute (2)
United States (137) · Canada (10) · France (9) · Italy (9) · Belgium (8) · Netherlands (8) · United Kingdom (8) · Germany (5) · Croatia (4) · Israel (4) · Austria (3) · Portugal (3) · Switzerland (3) · Puerto Rico (2) · Turkey (Türkiye) (2)
Judith Karp (6) · Sergio Amadori, MD (5) · Anjali Advani, MD (4) · B. Smith (4) · Roland Walter (4) · Alan K. Burnett, MD, FRCP (3) · Brenda Cooper, MD (3) · Brenda W. Cooper, MD (3) · Bruno de Medeiros (3) · Jerry Radich, MD (3) · Martin S. Tallman, MD (3) · Meir Wetzler, MD (3) · Thomas R. Chauncey, MD, PhD (3) · Anthony S. Stein, MD (2) · B. Douglas Smith, MD (2)
PMID 24383844, PMID 25527568, PMID 31375516, PMID 36184192, PMID 29926156, PMID 30523055, PMID 32499241, PMID 37267439, PMID 11331327, PMID 11585760, PMID 12750167, PMID 15339678, PMID 15514371, PMID 15761020, PMID 16275934, PMID 16484584, PMID 16670265, PMID 16932345, PMID 17315155, PMID 17339189, PMID 17562873, PMID 17640728, PMID 17910637, PMID 18571721, PMID 18769450, PMID 19010875, PMID 19092853, PMID 19109557, PMID 19286996, PMID 19289999, PMID 19291085, PMID 19710500, PMID 19794082, PMID 19804455, PMID 19826132, PMID 20038732, PMID 20451454, PMID 20460644, PMID 20522709, PMID 20716770, PMID 20952518, PMID 21239698, PMID 21393334, PMID 21551228, PMID 21791475, PMID 22001391, PMID 22002488, PMID 22133771, PMID 22627678, PMID 22733022
U01CA070095 (14), U10CA032102 (14), P30CA006973 (10), U10CA031946 (8), P30CA015704 (7), P30CA043703 (7), N01CM62204 (4), U10CA021115 (4), U10CA180821 (4), P30CA016056 (3), P30CA072720 (3), P30CA124435 (3), N01CM00100 (2), N01CM62202 (2), P30CA016672 (2)