5 completed, 1 terminated. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 5, Terminated 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Leishmaniasis, Visceral: new trials by email Literature Review of Leishmaniasis, Visceral trials Research Report on Leishmaniasis, Visceral
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects DNDI-0690, Placebo of DNDI-0690 - Visceral Leishmaniasis, Cutaneous Leishmaniases | Phase 1 | Completed | Drugs for Neglected Diseases | 64 | 2019-04-04 | 2022-12-20 |
| A First-in-human, Safety, Tolerability, and Pharmacokinetics Study of LXE408 in Healthy Subjects LXE408, Placebo, Iohexol - Visceral Leishmaniasis, Chagas Disease | Phase 1 | Completed | Novartis Pharmaceuticals | 88 | 2018-12-21 | 2026-09-09 |
| Steady State Global Bioequivalence Study of Amphotericin B Liposome for Injection 50 mg/ Vial in Fed Condition Amphotericin B Liposome, AmBisome (Amphotericin B) Liposome - Visceral Leishmaniasis | Phase 1 | Completed | Aurobindo Pharma Ltd | 140 | 2018-05-02 | 2019-08-26 |
| Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers LEISH-F3 + SLA-SE, LEISH-F3 + GLA-SE - Visceral Leishmaniasis | Phase 1 | Completed | Access to Advanced Health Institute (AAHI) | 39 | 2014-04-01 | 2016-02-23 |
| Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India Leish-111f + MPL-SE Adjuvant - Visceral Leishmaniasis, Post-kala-azar Dermal Leishmaniasis | Phase 1 | Completed | Access to Advanced Health Institute (AAHI) | 36 | 2007-04-01 | 2015-04-03 |
| Miltefosine for Brazilian Visceral Leishmaniasis Miltefosine: initially 2.5 mg/kg/day for 28 days - Kala Azar | Phase 1 / Phase 2 | Terminated | AB Foundation | 80 | 2005-04-01 | 2016-07-12 |
Chagas Disease (1) · Leishmaniasis (1) · Leishmaniasis, Cutaneous (1)
Euglenozoa Infections (6) · Infections (6) · Parasitic Diseases (6) · Protozoan Infections (6) · Vector Borne Diseases (6) · Leishmaniasis (5) · Skin Diseases (2) · Skin Diseases, Infectious (2) · Skin Diseases, Parasitic (2) · Skin and Connective Tissue Diseases (2) · Trypanosomiasis (1)
Amphotericin B (1) · Iohexol (1) · LXE408 (1) · Liposomes (1) · liposomal amphotericin B (1)
Access to Advanced Health Institute (AAHI) (2) · AB Foundation (1) · Aurobindo Pharma Ltd (1) · Drugs for Neglected Diseases (1) · Novartis Pharmaceuticals (1)
India (2) · United States (2) · Bangladesh (1) · Brazil (1) · United Kingdom (1)
Anna Marie Beckmann, PhD (1) · Dr. Dinesh Mondal, MD (1) · Dr. Krishna Pandey, MD (1) · Dr. Sajid Mohd, MD (1) · Dr. Shyam Sundar, MD (1) · Dr. Subhra Lahiri, Ph.D (1) · Franco M Piazza, MD, MPh (1) · Nagesh Meda, M.Pharm (1) · Reynaldo Dietze (1) · Sharan Sidhu, MD (1) · Shyam Sundar, MD (1)
2018 (1)