11 completed, 1 recruiting. 12 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 11, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Iron-deficiency: new trials by email Literature Review of Iron-deficiency trials Research Report on Iron-deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery) Ferric derisomaltose, Placebo - Gynecologic Cancer, Anemia | Phase 3 | Recruiting | AHS Cancer Control Alberta | 82 | 2025-04-08 | 2026-10-28 |
| Safety and Effectiveness of IHAT in Iron Deficient Pre-menopausal Woman Low dose IHAT, High Dose IHAT, Carob flour - Iron-deficiency | Phase 3 | Completed | RDC Clinical Pty Ltd | 180 | 2024-03-06 | 2025-03-10 |
| Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women Low Dose IHAT, High Dose IHAT, Carob Flour - Iron-deficiency | Phase 3 | Completed | Nemysis Ltd | 180 | 2024-03-05 | 2025-06-04 |
| Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF) Ferric Derisomaltose 1000 Mg in 100 mL INTRAVENOUS SOLUTION [Monoferric], Placebo - Iron-deficiency, Heart Failure With Preserved Ejection Fraction | Phase 2 / Phase 3 | Completed | Massachusetts General Hospital | 65 | 2021-11-26 | 2026-09-04 |
| Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years Ferric Maltol, Ferrous sulfate - Anemia, Iron-deficiency | Phase 3 | Completed | Shield Therapeutics | 65 | 2021-11-03 | 2025-11-10 |
| Iron Babies Pilot Supplementation Trial Iron drops/Ferrous sulphate, Placebo drops - Iron-deficiency, Anaemia in Early Infancy | Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 100 | 2021-08-03 | 2022-05-26 |
| Oral Iron Versus Oral Iron Plus a Web-based Behavioral Intervention in Young Children (IRONCHILD) Ferrous Sulfate, IRONCHILD - Iron Deficiency Anemia, Iron-deficiency | Phase 3 | Completed | Baylor College of Medicine | 1 | 2021-07-09 | 2023-05-06 |
| Iron Supplementation and Neurodevelopmental Outcome in ELGANs Iron Sulfate - Iron-deficiency | Phase 3 | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 51 | 2021-02-01 | 2024-11-12 |
| Intravenous Iron Carboxymaltose, Isomaltoside and Oral Iron Sulphate for Postpartum Anemia Iron Carboxymaltose, Iron Isomaltoside, Ferrous sulphate - Postpartum Anemia Nos, Iron-deficiency | Phase 3 | Completed | University Medical Centre Ljubljana | 300 | 2020-09-10 | 2022-06-27 |
| Effect of Ferric Carboxymaltose on Exercise Capacity After Kidney Transplantation Ferric carboxymaltose, Sodium chloride - Iron-deficiency, Transplant-Related Disorder | Phase 3 | Completed | University Medical Center Groningen | 148 | 2019-08-02 | 2024-08-27 |
| Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency / and Sub-Study Ferric Carboxymaltose, Placebo - Heart Failure, Iron-deficiency | Phase 3 | Completed | American Regent, Inc. | 3065 | 2017-03-15 | 2024-07-03 |
| A Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Administered by Infusions to Iron-deficient Blood Donors Iron isomaltoside 1000 (Monofer®), Placebo - Iron-deficiency | Phase 3 | Completed | Pharmacosmos A/S | 107 | 2013-06-01 | 2018-03-15 |
Anemia, Iron-Deficiency (12) · Iron Deficiencies (4) · Anemia (3) · Heart Failure (1)
Anemia, Hypochromic (12) · Hematologic Diseases (12) · Hemic and Lymphatic Diseases (12) · Iron Metabolism Disorders (12) · Metabolic Diseases (12) · Nutritional and Metabolic Diseases (12) · Anemia (9) · Iron Deficiencies (8) · Cardiovascular Diseases (1) · Heart Diseases (1)
ferrous sulfate (5) · ferric carboxymaltose (3) · Iron-Dextran Complex (2) · Saline Solution (2) · Sodium Chloride (2) · ferric derisomaltose (2) · iron isomaltoside 1000 (2) · locust bean gum (2) · FIT1 protein, Arabidopsis (1) · ferric maltol (1) · ferric trimaltol (1)
AHS Cancer Control Alberta (1) · American Regent, Inc. (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Baylor College of Medicine (1) · London School of Hygiene and Tropical Medicine (1) · Massachusetts General Hospital (1) · Nemysis Ltd (1) · Pharmacosmos A/S (1) · RDC Clinical Pty Ltd (1) · Shield Therapeutics (1) · University Medical Center Groningen (1) · University Medical Centre Ljubljana (1)
United States (5) · Australia (3) · Canada (2) · Bulgaria (1) · Czechia (1) · Denmark (1) · Georgia (1) · Hungary (1) · Latvia (1) · Lithuania (1) · Netherlands (1) · New Zealand (1) · Poland (1) · Puerto Rico (1) · Russia (1)
Adrian F Hernandez, MD (1) · Amanda Rao, PhD (1) · Carla Cerami, MD, PhD (1) · Greg Lewis, MD (1) · Jacquelyn M Powers, MD (1) · Janine Y Khan, MD, MBA (1) · Maria Cristina Comelli, PhD (1) · Martin de Borst, MD/PhD (1) · Miha Lucovnik, MD, PhD (1)
PMID 34003690, PMID 36874582, PMID 36948568, PMID 37598795, PMID 37632463, PMID 37945297, PMID 38250799, PMID 39890013, PMID 41137844, PMID 42733564
K23HL132001 (1), R01HL151841 (1)