4 recruiting, 3 completed, 3 terminated, 2 not yet recruiting. 3 Not applicable, 3 Phase 2, 2 Phase 1, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients Hospital-Based Vaccination Pathway - Chronic Disease, Immunocompromised | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1500 | 2026-02-01 | 2026-02-05 | |
| Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised Patients DaRT seeds - Squamous Cell Carcinoma, Alpha Radiation | Not applicable | Recruiting | Alpha Tau Medical LTD. | 28 | 2026-01-01 | 2026-07-15 |
| Clinical Study on Immunogenicity and Safety of Lyophilized Vero Cell-Derived Human Rabies Vaccine in Special Populations Observation Only - Rabies Exposure, Immunocompromised | Recruiting | Liaoning Chengda Biotechnology CO., LTD | 180 | 2025-08-15 | 2025-08-13 | |
| Extended Remdesivir Infusion Combined With Nirmatrelvir/Ritonavir for Persistent SARS-CoV-2 Infection in Immunocompromised Patients combination therapy, SOC - COVID-19, SARS-CoV-2 | Not applicable | Not yet recruiting | National Taiwan University Hospital | 40 | 2024-09-21 | 2024-09-25 |
| A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19 Nirmatrelvir, Ritonavir, Placebo for nirmatrelvir - Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19) | Phase 2 | Withdrawn | Pfizer | 2022-12-13 | 2023-03-01 | |
| A Study to Evaluate Efficacy and Safety of Casirivimab+Imdevimab (Monoclonal Antibodies) for Prevention of COVID-19 in Immunocompromised Adolescents and Adults casirivimab+imdevimab, Placebo - Immunocompromised | Phase 3 | Terminated | Regeneron Pharmaceuticals | 66 | 2021-10-25 | 2025-10-20 |
| COVID-19 Vaccination and Breakthrough Infections Among Persons With Immunocompromising Conditions in the United States BNT162b2 (Tozinameran) - Immunocompromised, Immunosuppressed | Completed | Pfizer | 1277747 | 2021-08-25 | 2024-02-12 | |
| Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study DAS181, Placebo, DAS181 COVID-19 - Lower Respiratory Tract Infection, Parainfluenza | Phase 3 | Recruiting | Ansun Biopharma, Inc. | 274 | 2019-05-23 | 2026-06-23 |
| Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes - Hematopoietic and Lymphoid Cell Neoplasm, Immunocompromised | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 16 | 2018-03-15 | 2026-09-04 |
| Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy High Flow Nasal Cannula or Low Flow Nasal Cannula - Immunocompromised, Hematologic Malignancy | Not applicable | Active not recruiting | Mount Sinai Hospital, Canada | 98 | 2018-01-10 | 2025-05-09 |
| Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients Invasive Fungal Disease, Fever and Neutropenia | Completed | Karius, Inc. | 40 | 2017-05-17 | 2019-06-17 | |
| A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis Micafungin - Immunocompromised, Bone Marrow Transplant | Phase 1 | Terminated | Children's Hospital Medical Center, Cincinnati | 9 | 2014-01-01 | 2018-05-23 |
| Seasonal Flu Vaccine in Adult Transplant Recipients Fluad 1x - Immunocompromised, Transplanted | Phase 2 | Completed | HepNet Study House, German Liverfoundation | 122 | 2010-11-01 | 2012-04-16 |
| Diagnosis of Invasive Pulmonary Aspergillosis by Direct Lung Tissue Aspergillus Galactomannan Antigen Detection From Aspirate by Ultrasound-guided Fine Needle Aspiration Lung aspiration - Immunocompromised | Unknown | National Taiwan University Hospital | 50 | 2010-03-01 | 2011-02-23 | |
| H1N1sw Vaccine in Adult Transplant Recipients Focetria (2x H1N1 vaccine with MF59 adjuvants) - Immunocompromised | Phase 2 | Terminated | HepNet Study House, German Liverfoundation | 13 | 2010-02-01 | 2012-04-16 |
COVID-19 (5) · Chronic Disease (2) · Coronavirus Infections (2) · Hematologic Neoplasms (2) · Neoplasms (2) · Autoimmune Diseases (1) · Breakthrough Infections (1) · Carcinoma, Squamous Cell (1) · Coronaviridae Infections (1) · Fever (1) · Frailty (1) · HIV Infections (1) · Hypoxia (1) · Infections (1) · Inflammatory Bowel Diseases (1)
Infections (6) · RNA Virus Infections (6) · Pathological Conditions, Signs and Symptoms (5) · Virus Diseases (5) · Coronaviridae Infections (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Lung Diseases (4) · Nidovirales Infections (4) · Pneumonia (4) · Pneumonia, Viral (4) · Respiratory Tract Diseases (4) · Respiratory Tract Infections (4) · Coronavirus Infections (3) · Disease Attributes (3)
Ritonavir (2) · nirmatrelvir (2) · BNT162 Vaccine (1) · Combined Modality Therapy (1) · Micafungin (1) · casirivimab (1) · casirivimab and imdevimab drug combination (1) · focetria (1) · imdevimab (1) · nirmatrelvir and ritonavir drug combination (1) · oplunofusp (1) · remdesivir (1)
HepNet Study House, German Liverfoundation (2) · National Taiwan University Hospital (2) · Pfizer (2) · Alpha Tau Medical LTD. (1) · Ansun Biopharma, Inc. (1) · Children's Hospital Medical Center, Cincinnati (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Karius, Inc. (1) · Liaoning Chengda Biotechnology CO., LTD (1) · M.D. Anderson Cancer Center (1) · Mount Sinai Hospital, Canada (1) · Regeneron Pharmaceuticals (1)
United States (8) · Taiwan (3) · China (2) · Germany (2) · Australia (1) · Bulgaria (1) · Canada (1) · Israel (1) · Mexico (1) · South Korea (1)
Amy Armstrong, MD (1) · David Marin (1) · Dr. Sangeeta Mehta, MD, FRCPC (1) · Fang Huang (1) · Hao-Chien Wang (1) · Liron Dimnik (1) · Michael P Manns, Prof (1) · Parinda Mehta, MD (1) · Patrizia Laurenti, Professor (1) · Ronald B Moss, MD (1)
2009 (1), 2018 (1)