Karius, Inc.: Clinical Trials

9 completed, 1 active not recruiting, 1 not yet recruiting, 1 recruiting. 2 Not applicable.

By phase and status

Phase	Trials	Status
Not applicable	2	Completed 1, Recruiting 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Metagenomic Sequencing Across the Infectious Disease Risk and Care Continuum Infectious Diseases, Immunocompromised Host		Not yet recruiting	Karius, Inc.	10000	2026-10-01	2026-09-17
Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients Metagenomic plasma-based test for agnostic pathogen detection - Infection, Infections, Bacterial	Not applicable	Recruiting	Karius, Inc.	2000	2025-10-27	2026-01-30
Pneumonia in the ImmunoCompromised - Use of the Karius Test for the Detection of Undiagnosed Pathogens Karius Test - Pneumonia, Bacterial, Pneumonia, Viral		Completed	Karius, Inc.	257	2019-11-05	2023-02-09
Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections Karius Test - Musculoskeletal Infection, Acute Hematogenous Osteomyelitis	Not applicable	Completed	Indiana University	38	2019-09-01	2023-12-01
Next Generation Sequencing Detection of Lyme Disease Lyme Disease, Pediatric Infectious Disease		Completed	Stony Brook University	15	2018-07-24	2022-02-25
Use of NGS Cell-free Pathogen Test for Identification of Low Risk Fever & Neutropenia in Pediatric Patients Karius Test - Neutropenia, Fever		Completed	Karius, Inc.	15	2018-05-07	2023-02-10
Next Generation Pathogen Sequencing for Prediction of Adverse Events Bloodstream Infection		Active not recruiting	St. Jude Children's Research Hospital	160	2017-08-09	2026-07-20
Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients Invasive Fungal Disease, Fever and Neutropenia		Completed	Karius, Inc.	40	2017-05-17	2019-06-17
Detection of Dengue Virus in Plasma of Patients in Nepal Dengue Fever		Completed	Karius, Inc.	643	2016-10-26	2023-02-14
Determining the Etiology of Febrile Neutropenia Using the Karius Sequencing-based Infectious Disease Diagnostic Assay Infection, Neutropenia		Completed	Karius, Inc.	57	2016-08-01	2018-05-11
The DISCOVER Trial (Diagnosis of Infection in Stem Cell Transplant Patients OVER Time) Bone Marrow Transplant Infection		Unknown	Karius, Inc.	70	2016-07-01	2023-03-08
Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay Bacteremia, Septicemia		Completed	Karius, Inc.	108	2016-07-01	2018-05-11
SEP-SEQ Trial - Determining the Etiology of Sepsis Using an Infectious Disease Diagnostic Sequencing Assay Sepsis		Completed	Karius, Inc.	350	2016-04-01	2017-10-27

Conditions studied

Infections (4)  ·  Neutropenia (3)  ·  Sepsis (3)  ·  Fever (2)  ·  Arthritis, Infectious (1)  ·  Bacteremia (1)  ·  Bacterial Infections (1)  ·  Communicable Diseases (1)  ·  Dengue (1)  ·  Glossitis, Benign Migratory (1)  ·  Hematologic Neoplasms (1)  ·  Invasive Fungal Infections (1)  ·  Lyme Disease (1)  ·  Mycoses (1)  ·  Neoplasms (1)

Countries

United States (11)  ·  Nepal (1)

Top investigators

Kat Kwiatkowski, PhD (2)  ·  Amy Armstrong, MD (1)  ·  Catherine Aftandillian, MD (1)  ·  Jack G Schneider, MD (1)  ·  Jose G Montoya, MD (1)  ·  Joshua Wolf, MBBS, BA (1)  ·  Krishna Manandhar, PhD (1)  ·  Peter Chin-Hong, MD (1)  ·  Samuel Yang, MD (1)  ·  Stanley C Deresinski, MD (1)  ·  Stephen Bergin, MD (1)  ·  Vance G Fowler, MD (1)

Results publications

PMID 31855231, PMID 33870413, PMID 37815489, PMID 41780551