12 completed, 1 recruiting, 1 terminated, 1 unknown. 4 Phase 2, 3 Not applicable, 3 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Not applicable | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
| Early Phase 1 | 1 | Completed 1 |
Follow Idiopathic Gastroparesis: new trials by email Literature Review of Idiopathic Gastroparesis trials Research Report on Idiopathic Gastroparesis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis. CIN-102 Dose 15mg, Placebo, CIN-102 Dose 10mg - Idiopathic Gastroparesis | Phase 2 | Completed | CinDome Pharma, Inc. | 416 | 2025-01-29 | 2026-07-13 |
| Open Label Safety Study of Tradipitant in Idiopathic and Diabetic Gastroparesis Tradipitant - Idiopathic Gastroparesis, Diabetic Gastroparesis | Phase 3 | Completed | Vanda Pharmaceuticals | 17 | 2024-01-09 | 2026-10-19 |
| A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis NG101, Placebo - Diabetic Gastroparesis, Idiopathic Gastroparesis | Phase 2 | Completed | Neurogastrx, Inc. | 161 | 2020-08-01 | 2025-08-28 |
| Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis Tradipitant, Placebo, Open Label Tradipitant - Idiopathic Gastroparesis, Diabetic Gastroparesis | Phase 3 | Completed | Vanda Pharmaceuticals | 979 | 2019-08-20 | 2026-09-24 |
| Gastroparesis Registry 3 Gastroparesis, Diabetic Gastroparesis | Completed | Johns Hopkins Bloomberg School of Public Health | 406 | 2019-01-24 | 2024-05-24 | |
| A Study to Evaluate the Efficacy and Safety of TAK-906 in Adult Participants With Symptomatic Idiopathic or Diabetic Gastroparesis TAK-906 Maleate, Placebo - Diabetic Gastroparesis, Idiopathic Gastroparesis | Phase 2 | Completed | Millennium Pharmaceuticals, Inc. | 242 | 2018-10-14 | 2022-11-16 |
| Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants TAK-954, Placebo - Diabetic Gastroparesis, Idiopathic Gastroparesis | Phase 2 | Completed | Takeda | 36 | 2018-01-02 | 2021-01-07 |
| G-POEM for Treatment of Refractory Gastroparesis Gastric Per Oral Endoscopic Myotomy - Diabetic Gastroparesis, Idiopathic Gastroparesis | Completed | Johns Hopkins University | 80 | 2015-05-01 | 2020-08-21 | |
| Effects of Global Osteopathic Manual Treatments in Patients With Idiopathic Gastroparesis Global Osteopathic Manual Treatment - Idiopathic Gastroparesis | Not applicable | Unknown | Kathleen Brannan Brown, Inc. | 12 | 2014-09-01 | 2015-04-01 |
| Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA) - Idiopathic Gastroparesis, Diabetic Gastroparesis | Not applicable | Completed | Texas Tech University Health Sciences Center, El Paso | 11 | 2013-03-01 | 2021-06-02 |
| A Pilot Study on the Efficacy and Safety of Olanzapine in Gastroparesis Olanzapine - Idiopathic Gastroparesis | Not applicable | Terminated | University of Michigan | 3 | 2013-01-01 | 2019-09-10 |
| Biomagnetic Characterization of Gastric Dysrhythmias III magnetogastrogram - Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis | Early Phase 1 | Completed | Vanderbilt University Medical Center | 22 | 2012-12-28 | 2026-04-22 |
| Gastroparesis Registry 2 Gastroparesis, Diabetic Gastroparesis | Completed | Johns Hopkins Bloomberg School of Public Health | 506 | 2012-07-01 | 2022-02-23 | |
| Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Rare Disorders, Undiagnosed Disorders | Recruiting | Sanford Health | 20000 | 2010-07-01 | 2025-05-29 | |
| Nortriptyline for Idiopathic Gastroparesis Nortriptyline Hydrochloride, Placebo (for nortriptyline) - Idiopathic Gastroparesis | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 130 | 2009-01-01 | 2020-05-14 |
Gastroparesis (9) · Nausea (4) · Vomiting (4) · Abdominal Pain (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1) · Addison Disease (1) · Alagille Syndrome (1) · Alstrom Syndrome (1) · Amnesia, Transient Global (1) · Aniridia (1) · Aniridia and Absent Patella (1) · Aniridia, Partial, with Unilateral Renal Agenesis and Psychomotor Retardation (1) · Ataxia (1)
Neurologic Manifestations (11) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Digestive System Diseases (10) · Gastrointestinal Diseases (10) · Paralysis (9) · Stomach Diseases (9) · Signs and Symptoms, Digestive (5) · Pain (2) · Abnormalities, Multiple (1) · Adrenal Gland Diseases (1) · Adrenal Insufficiency (1) · Amino Acid Metabolism, Inborn Errors (1) · Amino Acid Transport Disorders, Inborn (1) · Amnesia (1)
Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Nortriptyline (1) · Olanzapine (1)
Johns Hopkins Bloomberg School of Public Health (2) · Vanda Pharmaceuticals (2) · CinDome Pharma, Inc. (1) · Johns Hopkins University (1) · Kathleen Brannan Brown, Inc. (1) · Millennium Pharmaceuticals, Inc. (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Neurogastrx, Inc. (1) · Sanford Health (1) · Takeda (1) · Texas Tech University Health Sciences Center, El Paso (1) · University of Michigan (1) · Vanderbilt University Medical Center (1)
United States (14) · Belgium (2) · Australia (1) · Germany (1) · Japan (1) · Poland (1)
Braden Kuo, MD (2) · Frank Hamilton, MD, MPH (2) · Allen Lee, MD (1) · Henry Parkman, MD (1) · Leonard A Bradshaw, PhD (1) · Mohamed O Othman, MD (1) · Mouen A Khashab, MD (1) · Pankaj J Pasricha, MD (1) · William Hasler, MD (1)
PMID 22415019, PMID 22735166, PMID 24368464, PMID 24398454, PMID 26318833, PMID 26595907, PMID 26839980, PMID 27781342, PMID 28970332, PMID 29487566, PMID 30404035, PMID 30852767, PMID 31758430, PMID 32930463, PMID 33130007, PMID 33493377, PMID 33548234, PMID 33711180, PMID 33741641, PMID 34089855, PMID 34595805, PMID 34967147, PMID 35502871, PMID 37533380, PMID 38237696, PMID 40367443, PMID 42779231
U01DK073974 (3), U01DK073975 (3), U01DK073983 (3), U01DK074007 (3), U01DK073985 (2), U01DK074008 (2), 2018 (1), R01DK058697 (1), U01DK074035 (1), U01DK112193 (1), U24DK074008 (1)