4 terminated. 4 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Terminated 4 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Hypertrophy: new trials by email Literature Review of Hypertrophy trials Research Report on Hypertrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia Rigosertib, Questionnaire - Leukemia, Myelofibrosis | Phase 2 | Terminated | M.D. Anderson Cancer Center | 3 | 2017-08-16 | 2020-08-07 |
| Nivolumab in Treating Patients With Primary Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis, or Post-Polycythemia Vera Myelofibrosis Laboratory Biomarker Analysis, Nivolumab, Quality-of-Life Assessment - Hepatomegaly, Myelofibrosis Transformation in Essential Thrombocythemia | Phase 2 | Terminated | M.D. Anderson Cancer Center | 8 | 2015-05-14 | 2019-05-15 |
| A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure MYDICAR Phase 1, MYDICAR Phase 2, Placebo Phase 2 only - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Celladon Corporation | 9 | 2015-04-01 | 2017-01-31 |
| Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy Eleclazine, Placebo - Hypertrophic Cardiomyopathy | Phase 2 / Phase 3 | Terminated | Gilead Sciences | 172 | 2015-02-05 | 2018-09-24 |
Cardiomyopathies (2) · Heart Failure (2) · Primary Myelofibrosis (2) · Splenomegaly (2) · Anemia (1) · Angina Pectoris (1) · Cardiomegaly (1) · Cardiomyopathy, Hypertrophic (1) · Cardiomyopathy, Hypertrophic, Familial (1) · Cardiovascular Diseases (1) · Dyspnea (1) · Heart Diseases (1) · Hepatomegaly (1) · Leukemia (1)
Pathological Conditions, Anatomical (4) · Pathological Conditions, Signs and Symptoms (4) · Bone Marrow Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Myeloproliferative Disorders (2) · Neoplasms (2) · Aortic Stenosis, Subvalvular (1) · Aortic Valve Disease (1) · Aortic Valve Stenosis (1) · Bone Marrow Neoplasms (1) · Cardiovascular Diseases (1) · Chest Pain (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Nivolumab (1) · ON 01910 (1) · Surveys and Questionnaires (1) · eleclazine (1)
M.D. Anderson Cancer Center (2) · Celladon Corporation (1) · Gilead Sciences (1)
United States (4) · Australia (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Netherlands (1) · United Kingdom (1)
Jorge Cortes, MD (1) · Srdan Verstovsek (1)
P30CA016672 (1)