52 completed, 12 unknown, 4 recruiting, 3 terminated. 28 Not applicable, 6 Phase 1, 6 Phase 2, 3 Phase 4, 2 Phase 3.
Follow Human Papillomavirus: new trials by email Literature Review of Human Papillomavirus trials Research Report on Human Papillomavirus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya Artesunate vaginal inserts, Placebo vaginal inserts - Human Immunodeficiency Virus, Human Papillomavirus | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 120 | 2025-01-22 | 2026-05-14 |
| Knowledge of 18-19 Years Old About Papillomavirus and HPV Vaccination Data collection - Human Papillomavirus | Completed | Université de Reims Champagne-Ardenne | 29 | 2024-12-01 | 2026-02-18 | |
| Comparisons of the Effects and Clinical Outcomes of CH2 Vaginal Gel Versus Placebo on CIN1 CH2 vaginal gel, Placebo hyaluronic acid gel - Cervical Intraepithelial Neoplasia, Human Papillomavirus | Not applicable | Active not recruiting | National Taiwan University Hospital | 50 | 2024-09-30 | 2025-11-19 |
| Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV) Novel point-of-care diagnostic test for detecting HPV ("Rice HPV test") - Human Papillomavirus | Recruiting | M.D. Anderson Cancer Center | 600 | 2024-07-23 | 2026-05-18 | |
| Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV 5 Fluorouracil (5 FU) Cream, Placebo - Cervical Cancer, CIN2 | Not applicable | Completed | UNC Lineberger Comprehensive Cancer Center | 180 | 2023-03-22 | 2026-08-21 |
| Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old) 9-valent HPV vaccine, 2 doses alternate timing, 9-valent HPV vaccine, 3 doses standard timing - Immunization, HPV Infection | Phase 4 | Recruiting | The University of Texas Medical Branch, Galveston | 618 | 2023-01-18 | 2026-09-15 |
| Multi-site HPV Screening by High-throughput Sequencing in Patients With Chronic HPV-HR Infection Followed by Gynecology Smear - Human Papillomavirus | Not applicable | Unknown | University Hospital, Toulouse | 30 | 2022-06-21 | 2024-07-19 |
| Provider Recommendation and HPV Vaccination Local Tailoring implementation strategy, Prescribed Strategy - Human Papillomavirus | Not applicable | Recruiting | Kaiser Permanente | 301201 | 2022-03-21 | 2025-05-20 |
| Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune) Human Papillomavirus | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 850 | 2021-11-17 | 2026-07-06 | |
| A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers Bintrafusp Alfa, PDS01ADC, Entinostat - Oropharyngeal Cancer, Neck Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 55 | 2021-10-05 | 2026-09-22 |
| Alinity m HR HPV Specimen Collection Study From Women Undergoing Routine Cervical Cancer Screening Alinity m HR HPV - Human Papillomavirus | Completed | Abbott Molecular | 14935 | 2021-02-16 | 2024-02-12 | |
| Comparing Strategies for Implementing Primary HPV Screening Local Tailoring - Cervical Cancer, Human Papillomavirus | Not applicable | Unknown | Chun Chao | 45000 | 2019-03-01 | 2021-12-30 |
| HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma A multi-omics analysis - Cervical Adenocarcinoma, Human Papillomavirus | Unknown | Lei Li | 40 | 2018-11-10 | 2018-11-15 | |
| Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions Aldesleukin, E6 T Cell Receptor (TCR) - Human Papillomavirus, HPV-16 | Phase 1 | Terminated | National Cancer Institute (NCI) | 1 | 2018-01-09 | 2021-02-16 |
| txt2protect: Using Text Messaging to Increase HPV Vaccination Among Young Sexual Minority Men txt2protect, Sexual Health Control - Human Papillomavirus | Not applicable | Completed | Northwestern University | 150 | 2018-01-03 | 2020-07-20 |
| Long Term Immune Memory Responses to HPV Vaccination Following 2 vs 3 Doses of Quad-HPV Vaccine Human Papillomavirus 9-valent Vaccine, Recombinant - Human Papillomavirus | Phase 4 | Completed | University of British Columbia | 18 | 2017-09-11 | 2021-06-25 |
| Longitudinal HPV Pap in CIN and VAIN HPV test and Pap Smear - Cervical Intraepithelial Neoplasia, Hysterectomy | Unknown | Chang Gung Memorial Hospital | 600 | 2017-07-01 | 2023-07-05 | |
| Increasing Uptake of Evidence-Based Screening Services Through CHW-led Multi-modality Intervention OraQuick Swab, Fecal Immunochemical Test, OraQuick Fingerstick - Human Papillomavirus, Human Immunodeficiency Virus | Not applicable | Completed | University of Miami | 754 | 2017-04-11 | 2021-12-28 |
| Safety and Tolerability of GX-I7 in HPV-infected Female Volunteers GX-I7, Placebo - Human Papillomavirus | Phase 1 | Completed | Genexine, Inc. | 32 | 2017-02-16 | 2018-10-23 |
| Human Papillomavirus in Young People Epidemiological Research 2 (HYPER2) Human Papillomavirus, Human Papillomavirus Infection | Completed | The Alfred | 200 | 2017-01-16 | 2022-10-05 |
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Uterine Cervical Neoplasms (18) · Uterine Cervical Dysplasia (9) · Acquired Immunodeficiency Syndrome (5) · Neoplasms (4) · Papillomavirus Infections (4) · Squamous Intraepithelial Lesions (4) · Anus Neoplasms (3) · Behavior (3) · Homosexuality (3) · Infections (3) · Oropharyngeal Neoplasms (3) · Carcinoma, Squamous Cell (2) · Head and Neck Neoplasms (2) · Sexually Transmitted Diseases (2) · Squamous Cell Carcinoma of Head and Neck (2)
Genital Diseases (30) · Neoplasms (30) · Urogenital Diseases (30) · Female Urogenital Diseases (25) · Female Urogenital Diseases and Pregnancy Complications (25) · Genital Diseases, Female (25) · Uterine Cervical Diseases (24) · Uterine Diseases (24) · Neoplasms by Site (23) · Genital Neoplasms, Female (18) · Urogenital Neoplasms (18) · Uterine Neoplasms (18) · Infections (13) · Pathological Conditions, Signs and Symptoms (12) · Communicable Diseases (11)
Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (5) · Papillomavirus Vaccines (4) · Colposcopy (2) · Adjuvants, Pharmaceutic (1) · Antigens (1) · Community-Based Participatory Research (1) · Counseling (1) · Cryotherapy (1) · Data Collection (1) · Fluorouracil (1) · GPI0100 (1) · Gene-Eden-VIR (1) · Human Papillomavirus Recombinant Vaccine nonavalent (1) · Interleukin-2 (1) · Observation (1)
National Cancer Institute (NCI) (3) · National Taiwan University Hospital (3) · Preventive Oncology International, Inc. (3) · Shanghai Zerun Biotechnology Co.,Ltd (3) · The Alfred (3) · UNC Lineberger Comprehensive Cancer Center (3) · Chang Gung Memorial Hospital (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · University Hospital, Toulouse (2) · University of California, Los Angeles (2) · University of North Carolina, Chapel Hill (2) · Abbott Molecular (1) · Barretos Cancer Hospital (1) · Becton, Dickinson and Company (1) · Centre Hospitalier Universitaire de Besancon (1)
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Jerome L Belinson, MD (3) · Anna Giuliano, Ph.D. (2) · Chun R Chao, PhD (2) · Rufiang Wu, MD (2) · Abbey B Berenson, MD, PhD (1) · Amanda Dempsey, MD, PhD, MPH (1) · Andrea Lisco, M.D. (1) · Andrew Sikora, MD, PhD (1) · Anna-Barbara Moscicki, MD (1) · Anne De Groot, M.D. (1) · Annika Antonsson, Dr (1) · Ben Panizza, Assoc Prof (1) · Bernard F. Fuemmeler, PhD (1) · Brian Mustanski, PhD (1)
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P50CA101451 (1), R01AI113305 (1), R01CA143130 (1), R01CA183891 (1), R01CA250850 (1), R01CA255872 (1), R21CA208329 (1), R34CA284983 (1), R37CA051323 (1), U01MD010614 (1)