2 not yet recruiting, 1 active not recruiting, 1 completed, 1 recruiting. 2 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 2 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow HPV Disease: new trials by email Literature Review of HPV Disease trials Research Report on HPV Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of EGCG, Folic Acid, Vitamin B12 and Hyaluronic Acid on HPV DNA Integration Epigallocatechin gallate (EGCG), Folic Acid (FA), Vitamin B12 (B12), and Hyaluronic Acid (HA) - HPV Infection, HPV Integration | Not applicable | Not yet recruiting | IRCCS San Raffaele | 42 | 2026-07-01 | 2026-07-13 |
| HIFU vs Observation for LSIL of Cervix: A Randomized Controlled Trial HIFU treatment - HPV Disease, Cervical Intraepithelial Neoplasia Grade I | Not applicable | Not yet recruiting | Queen Mary Hospital, Hong Kong | 180 | 2026-05-01 | 2026-03-10 |
| Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) Artesunate ointment, Placebo ointment - Vulvar Diseases, HPV Infection | Phase 2 | Recruiting | Frantz Viral Therapeutics, LLC | 27 | 2023-12-06 | 2025-08-14 |
| Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL Artesunate, Placebo - Anal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition | Phase 2 | Active not recruiting | Frantz Viral Therapeutics, LLC | 17 | 2023-02-10 | 2025-05-18 |
| Vaccine Therapy With or Without Imiquimod in Treating Patients With Grade 3 Cervical Intraepithelial Neoplasia TA-HPV, pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine, imiquimod - Cervical Cancer, Precancerous Condition | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 75 | 2008-11-01 | 2023-08-31 |
Papillomavirus Infections (3) · Precancerous Conditions (1) · Uterine Cervical Dysplasia (1) · Uterine Cervical Neoplasms (1) · Vulvar Diseases (1)
Genital Diseases (4) · Urogenital Diseases (4) · Communicable Diseases (3) · DNA Virus Infections (3) · Disease Attributes (3) · Infections (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Sexually Transmitted Diseases (3) · Sexually Transmitted Diseases, Viral (3) · Tumor Virus Infections (3) · Virus Diseases (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases, Female (2)
artemisinin (2) · artenimol (2) · artesunic acid (2) · Artesunate (1) · Folic Acid (1) · Hyaluronic Acid (1) · Imiquimod (1) · Vitamin B 12 (1) · epigallocatechin gallate (1) · human papillomavirus vaccine, TA (1)
Frantz Viral Therapeutics, LLC (2) · IRCCS San Raffaele (1) · Queen Mary Hospital, Hong Kong (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
United States (3) · Italy (1)
Cornelia L. Trimble, MD (1) · Joel Palefsky, MD (1)
PMID 24477000, PMID 26420854, PMID 33468698
P50CA098252 (1), R21CA123876 (1)