1 active not recruiting, 1 completed, 1 not yet recruiting, 1 recruiting. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Focal Cortical Dysplasia: new trials by email Literature Review of Focal Cortical Dysplasia trials Research Report on Focal Cortical Dysplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorescence Guided Focal Cortical Dysplasia Surgery 5-ALA (Gliolan) - Drug Resistant Epilepsy | Phase 2 | Not yet recruiting | Hospices Civils de Lyon | 5 | 2026-09-01 | 2026-06-18 |
| Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME) SVG103 - Focal Cortical Dysplasia, Tuberous Sclerosis Complex (TSC) | Phase 1 / Phase 2 | Recruiting | Sovargen | 12 | 2026-07-14 | 2026-08-10 |
| Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II Radiprodil - Tuberous Sclerosis Complex, Focal Cortical Dysplasia | Phase 1 / Phase 2 | Active not recruiting | GRIN Therapeutics, Inc. | 30 | 2024-07-10 | 2026-04-01 |
| A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD Everolimus - Epilepsy, Tuberous Sclerosis Complex | Phase 2 | Completed | NYU Langone Health | 15 | 2014-01-01 | 2021-09-01 |
Tuberous Sclerosis (3) · Epilepsy (2) · Drug Resistant Epilepsy (1) · Hemimegalencephaly (1)
Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Malformations of Cortical Development (4) · Malformations of Cortical Development, Group I (4) · Nervous System Diseases (4) · Nervous System Malformations (4) · Genetic Diseases, Inborn (3) · Hamartoma (3) · Heredodegenerative Disorders, Nervous System (3) · Neoplasms (3) · Neoplasms, Multiple Primary (3) · Neoplastic Syndromes, Hereditary (3) · Neurocutaneous Syndromes (3) · Neurodegenerative Diseases (3) · Brain Diseases (2)
Everolimus (1) · radiprodil (1)
GRIN Therapeutics, Inc. (1) · Hospices Civils de Lyon (1) · NYU Langone Health (1) · Sovargen (1)
Australia (2) · Belgium (1) · Canada (1) · France (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1) · United Kingdom (1) · United States (1)
2023 (1), 2025 (1)