9 recruiting, 2 completed, 1 enrolling by invitation, 1 terminated. 2 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Enrolling by invitation 1 |
| Phase 2 | 1 | Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Fetal Growth Restriction (FGR): new trials by email Literature Review of Fetal Growth Restriction (FGR) trials Research Report on Fetal Growth Restriction (FGR)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Advancing Stillbirth Prevention Through Innovative Risk Evaluation (ASPIRE) Clinical Study None (this is an observational study with no intervention) - GDM, Preterm Preeclampsia | Recruiting | Medicines360 | 5500 | 2026-09-08 | 2026-09-30 | |
| DIFFUSION WEIGHTED MRI FINDINGS IN FETUSES WITH AND WITHOUT FETAL GROWTH RESTRICTION Diffusion-weighted fetal brain MRI - Fetal Growth Restriction (FGR) | Recruiting | Istanbul Training and Research Hospital | 120 | 2026-03-26 | 2026-08-20 | |
| Placental Biology in Health and Disease There are no interventions for this study - Pre-eclampsia, Gestational Diabetes Mellitus (GDM) | Recruiting | University of Oxford | 360 | 2025-12-16 | 2026-07-23 | |
| Placental Imaging Techniques ultrafast power Doppler imaging (uPDI) / quantitative ultrasound (QUS) - Fetal Growth Restriction (FGR), Placental Insufficiency | Not applicable | Recruiting | Carilion Clinic | 60 | 2025-04-23 | 2026-05-22 |
| Amniotic Fluid & the Preterm Gut Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn | Recruiting | Maxima Medical Center | 275 | 2024-10-14 | 2025-09-03 | |
| Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome Fetal Growth Restriction (FGR), Preeclampsia | Recruiting | Aristotle University Of Thessaloniki | 12084 | 2024-10-01 | 2025-04-09 | |
| Cord Blood S100B Protein Concentration in Neonates With Fetal Growth Restriction Prenatal ultrasound examination with blood flow analysis, Umbilical cord blood gas analysis, Umbilical cord blood S100B protein level - s100b, Hypoxia-Ischemia, Brain | Recruiting | Institute of Mother and Child, Warsaw, Poland | 120 | 2024-06-18 | 2025-03-25 | |
| AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study new ultrasound index and MRI - Fetal Growth Restriction (FGR) | Recruiting | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 300 | 2023-01-01 | 2026-03-16 | |
| Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR) Melatonin, Placebo - Fetal Growth Restriction (FGR) | Phase 1 | Enrolling by invitation | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 240 | 2023-01-01 | 2026-04-24 |
| Enhancing Prediction of Adverse Pregnancy Outcomes in Africa Through Partnerships and Innovation Fetal Growth Restriction (FGR), Preterm Birth | Recruiting | Makerere University | 4000 | 2022-07-25 | 2026-09-28 | |
| Observational Study on Fetal Growth Restriction Complicated by Early Flowmetric Alterations Fetal Growth Restriction (FGR) | Completed | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 63 | 2021-05-15 | 2024-12-05 | |
| Diagnostic Value of sFlt-1/PlGF Ratio for the Etiology of Intra Uterine Growth Restriction - ANGIOPAG Blood test at time of inclusion for sFlt-1/PlGF ratio, Follow-up blood test 2 to 4 weeks after inclusion, Placenta analysis for all included patients, even in case of normal birthweight - Intrauterine Growth Restriction, Fetal Growth Restriction (FGR) | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 167 | 2020-01-08 | 2026-08-12 |
| Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction Sildenafil, Placebo - Intrauterine Growth Restriction (IUGR), Fetal Growth Restriction (FGR) | Phase 2 / Phase 3 | Terminated | University of British Columbia | 21 | 2017-01-01 | 2020-02-11 |
Fetal Growth Retardation (13) · Pre-Eclampsia (5) · Pregnancy Complications (2) · Stillbirth (2) · Abruptio Placentae (1) · Chorioamnionitis (1) · Diabetes, Gestational (1) · Fetal Membranes, Premature Rupture (1) · Hypertension, Pregnancy-Induced (1) · Hypoxia-Ischemia, Brain (1) · Neonatal Sepsis (1) · Placenta Previa (1) · Placental Insufficiency (1) · Premature Birth (1) · Vasa Previa (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Fetal Diseases (13) · Growth Disorders (13) · Pathologic Processes (13) · Pathological Conditions, Signs and Symptoms (13) · Urogenital Diseases (13) · Pregnancy Complications (11) · Hypertension, Pregnancy-Induced (4) · Placenta Diseases (4) · Obstetric Labor Complications (3) · Cardiovascular Diseases (2) · Death (2) · Fetal Death (2) · Vascular Diseases (2)
Magnetic Resonance Spectroscopy (1) · Melatonin (1) · Sildenafil Citrate (1)
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (2) · Aristotle University Of Thessaloniki (1) · Assistance Publique - Hôpitaux de Paris (1) · Carilion Clinic (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Institute of Mother and Child, Warsaw, Poland (1) · Istanbul Training and Research Hospital (1) · Makerere University (1) · Maxima Medical Center (1) · Medicines360 (1) · University of British Columbia (1) · University of Oxford (1)
China (2) · United States (2) · Bulgaria (1) · Canada (1) · France (1) · Greece (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1) · Turkey (Türkiye) (1) · Uganda (1) · United Kingdom (1)
Agnieszka A. Drozdowska-Szymczak, MD, PhD (1) · Annettee Olivia Nakimuli, MBChB, MMED, MBA, PhD (1) · Giuliana Simonazzi, MD (1) · Jeanne Sibiude, MD, PhD (1) · Kenneth Lim, MD FRCSC (1) · Megan D Whitham, MD (1) · Peter von Dadelszen, BMedSc, MBChB, DipObst, DPhil, (1)
PMID 26909227, PMID 27658190, PMID 29282009, PMID 35359891, PMID 35799272, PMID 41602874, PMID 42555630