17 completed. 17 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 17 | Completed 17 |
| Phase 2 | 5 | Completed 5 |
Follow Fecal Incontinence: new trials by email Literature Review of Fecal Incontinence trials Research Report on Fecal Incontinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Single Dose Tadalafil on Urethral and Anal Closure Function Tadalafil 40 MG, Placebo - Urinary Incontinence,Stress, Fecal Incontinence | Phase 1 | Completed | University Hospital Bispebjerg and Frederiksberg | 24 | 2021-08-01 | 2022-04-06 |
| Effects of Single Dose Citalopram and Reboxetine on Urethral and Anal Closure Function on Healthy Female Subjects Citalopram 40mg, Reboxetine 8 mg, Placebo oral tablet - Stress Urinary Incontinence, Fecal Incontinence | Phase 1 | Completed | University Hospital Bispebjerg and Frederiksberg | 24 | 2019-09-17 | 2021-06-09 |
| Does Single Dose Imipramine Affect the Opening Pressure of the Urethral and Anal Sphincter? Placebo Oral Tablet, Imipramine Hydrochloride 25 MG - Urinary Incontinence, Stress, Fecal Incontinence | Phase 1 | Completed | Jonatan Kornholt | 16 | 2017-05-16 | 2021-02-12 |
| Treatment of Fecal Incontinence Using Allogenic-Adipose-derived Mesenchymal Stem Cells: A Prospective, Dose Escalation, Randomized, Placebo-controlled, Parallel-group, Single-blind, Single-center Pilot Study ALLO-ASC injection, Placebo - Fecal Incontinence | Phase 1 | Completed | Yonsei University | 21 | 2014-12-01 | 2018-08-13 |
| The Effect of Oxymetazoline Gel on Anal Pressure and Incontinence in Spinal Cord Injury Patients Oxymetazoline gel, Placebo gel - Fecal Incontinence, Spinal Cord Injury | Phase 1 / Phase 2 | Completed | RDD Pharma Ltd | 19 | 2014-11-01 | 2015-07-28 |
| Endoscopically Assisted Colostomy With Colopexy for Critically Ill Patients Without General Anesthesia or Laparotomy ENDOSCOPICALLY ASSISTED COLOSTOMY WITH COLOPEXY - Colonic Neoplasms, Rectal Neoplasms | Phase 1 | Completed | University of Sao Paulo | 5 | 2014-02-01 | 2014-12-04 |
| Autologous Cell Therapy for Treatment of Fecal Incontinence Iltamiocel - Fecal Incontinence | Phase 1 / Phase 2 | Completed | Cook MyoSite | 53 | 2013-03-28 | 2024-02-16 |
| An Study to Examine the Effect of Coated Suppositories on Anal Pressure in Healthy Subjects coated suppository - Fecal Incontinence | Phase 1 / Phase 2 | Completed | RDD Pharma Ltd | 6 | 2011-08-01 | 2011-08-23 |
| Effect of 7 Days of Dosing With a 10 mg Rectal Suppository of NRL001in Patients With Faecal Incontinence NRL001, Placebo control - Fecal Incontinence | Phase 1 | Completed | Norgine | 14 | 2010-08-01 | 2012-11-05 |
| Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of a Single Rectal Application of 10 mg NRL001 in Elderly Subjects NRL001, Placebo - Fecal Incontinence | Phase 1 | Completed | Norgine | 26 | 2010-04-01 | 2010-12-24 |
| Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of 7.5, 10, 12.5 or 15 mg NRL001 in a 2 g Suppository for 14 Days NRL001, Placebo - Fecal Incontinence | Phase 1 | Completed | Norgine | 48 | 2010-03-01 | 2010-12-24 |
| Study to Investigate Safety and Response to 1 or 2 g Rectal Suppositories Containing 5 or 10 mg NRL001. NRL001 - Fecal Incontinence | Phase 1 | Completed | Norgine | 36 | 2009-02-01 | 2009-12-23 |
| Evaluation of Outcomes of Restoring Pelvic Floor Support With TOPAS in Women With Moderate Fecal Incontinence Symptoms TOPAS - Fecal Incontinence | Phase 1 / Phase 2 | Completed | ASTORA Women's Health | 29 | 2007-09-01 | 2016-05-23 |
| Safety and Tolerability of a Single Intra-anal Dose of NRL001 in Healthy Volunteers Placebo control, NRL001 cream - Fecal Incontinence | Phase 1 | Completed | Norgine | 12 | 2007-04-01 | 2011-08-01 |
| Effect of Single Doses of 10 mg NRL001 Applied as a Suppository to the Anal Canal or Rectum NRL001 - Fecal Incontinence | Phase 1 | Completed | Norgine | 24 | 2007-04-01 | 2009-05-06 |
| A Randomized, Controlled, Clinical Trial of Biofeedback and Anal Injections as First Treatment of Fecal Incontinence 1. Anal injection, 2. Biofeedback - Fecal Incontinence | Phase 1 | Completed | University Hospital of North Norway | 126 | 2006-05-01 | 2011-11-17 |
| Safety and Efficacy of Anorectal Application of Dx-gel for Treatment of Anal Incontinence Anal injection of Nasha Dx - Fecal Incontinence | Phase 1 / Phase 2 | Completed | Uppsala University Hospital | 35 | 2004-02-01 | 2011-06-28 |
Urinary Incontinence, Stress (3) · Colonic Neoplasms (1) · Encopresis (1) · Gastrointestinal Diseases (1) · Intestinal Diseases (1) · Patient Satisfaction (1) · Rectal Diseases (1) · Rectal Neoplasms (1) · Spinal Cord Injuries (1) · Urinary Incontinence (1)
Digestive System Diseases (17) · Gastrointestinal Diseases (16) · Intestinal Diseases (16) · Rectal Diseases (16) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Lower Urinary Tract Symptoms (4) · Male Urogenital Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Urination Disorders (4) · Urogenital Diseases (4) · Urologic Diseases (4) · Urological Manifestations (4) · Urinary Incontinence (3)
dextranomer-hyaluronic acid copolymer (2) · Citalopram (1) · Fibrin Tissue Adhesive (1) · Imipramine (1) · Reboxetine (1) · Saline Solution (1) · Tadalafil (1)
Norgine (6) · RDD Pharma Ltd (2) · University Hospital Bispebjerg and Frederiksberg (2) · ASTORA Women's Health (1) · Cook MyoSite (1) · Jonatan Kornholt (1) · University Hospital of North Norway (1) · University of Sao Paulo (1) · Uppsala University Hospital (1) · Yonsei University (1)
United Kingdom (6) · Denmark (3) · Brazil (1) · Bulgaria (1) · Canada (1) · Hungary (1) · Israel (1) · Norway (1) · South Korea (1) · Sweden (1) · United States (1)
David Bell, MRCGP MFPM (2) · Anders Mellgren, MD, PhD (1) · Barthold Vonen, M.D., Ph.D. (1) · Hans Gruss, MD PhD (1) · Jesper Sonne, DMSc (1) · John H Scholefield (1) · John H Scholefield, MD (1) · Jonatan Kornholt, MD (1) · Jonathan A Simpson, MD (1) · Leonardo A Bustamante, MD (1) · Manoj J Raval, MD (1) · Michael Shapiro, MD (1) · Thea Christoffersen (1) · Wilhelm JR Graf, Prof. (1)
PMID 10496568, PMID 12576903, PMID 1929133, PMID 19581853, PMID 24499492, PMID 24499494, PMID 24499495, PMID 24763157, PMID 26888731, PMID 37144409, PMID 38456894, PMID 39076155, PMID 39167201
2009 (2), 2019 (1)