3 recruiting. 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 3 |
Follow Endodermal Sinus Tumor: new trials by email Literature Review of Endodermal Sinus Tumor trials Research Report on Endodermal Sinus Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells SC-CAR.GPC3xIL15.21 CAR T cells - Solid Tumor (Excluding CNS), Liver Cell Carcinoma | Phase 1 | Recruiting | Seattle Children's Hospital | 21 | 2025-12-22 | 2026-02-17 |
| Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells 21.15.GPC3-CAR T cells - Hepatoblastoma, Hepatocellular Carcinoma | Phase 1 | Recruiting | Baylor College of Medicine | 21 | 2025-06-10 | 2025-11-03 |
| Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors CARE T cells - Liver Cancer, Rhabdomyosarcoma | Phase 1 | Recruiting | Baylor College of Medicine | 24 | 2024-05-24 | 2026-08-06 |
Liposarcoma (3) · Rhabdoid Tumor (3) · Rhabdomyosarcoma (3) · Wilms Tumor (3) · Carcinoma, Hepatocellular (2) · Hepatoblastoma (2) · Liver Neoplasms (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Diseases (3) · Digestive System Neoplasms (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genetic Diseases, Inborn (3) · Kidney Diseases (3) · Kidney Neoplasms (3) · Liver Diseases (3) · Male Urogenital Diseases (3) · Mesonephroma (3) · Myosarcoma (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3)
Baylor College of Medicine (2) · Seattle Children's Hospital (1)
United States (3)
David Steffin, MD (2) · Colleen Annesley, MD (1) · Corinne Summers, MD (1) · Premal Lulla, MD (1)