3 completed. 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
Follow Drug-resistant Tuberculosis: new trials by email Literature Review of Drug-resistant Tuberculosis trials Research Report on Drug-resistant Tuberculosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults TBAJ-876, Midazolam, Digoxin - Pulmonary Disease, Tuberculosis, Pulmonary | Phase 1 | Completed | Global Alliance for TB Drug Development | 28 | 2022-06-30 | 2024-10-08 |
| Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults TBAJ-876 suspension, Placebo suspension, TBAJ-876 100 mg tablet - Pulmonary Disease, Tuberculosis, Pulmonary | Phase 1 | Completed | Global Alliance for TB Drug Development | 137 | 2020-06-08 | 2025-06-04 |
| Brief Bactericidal Activity of Anti-Tuberculosis Drugs High dose isoniazid - Tuberculosis, Drug-resistant Tuberculosis | Phase 1 | Completed | Centers for Disease Control and Prevention | 18 | 2015-11-01 | 2020-10-19 |
Tuberculosis (3) · Tuberculosis, Multidrug-Resistant (3) · Lung Diseases (2) · Tuberculosis, Pulmonary (2)
Actinomycetales Infections (3) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Gram-Positive Bacterial Infections (3) · Infections (3) · Mycobacterium Infections (3) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2)
TBAJ-876 (2) · Digoxin (1) · Isoniazid (1) · Midazolam (1) · Tablets (1)
Global Alliance for TB Drug Development (2) · Centers for Disease Control and Prevention (1)
United States (2) · India (1)
Antonio Lombardi, MD (2) · J. P. Cegielski, MD, MPH (1) · Sarah E. Smith-Jeffcoat, MPH (1)