13 completed, 2 terminated, 1 unknown, 1 withdrawn. 7 Phase 1, 5 Phase 2, 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Terminated 1, Unknown 1 |
| Phase 2 | 5 | Completed 3, Terminated 1, Unknown 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
Follow Disseminated Neuroblastoma: new trials by email Literature Review of Disseminated Neuroblastoma trials Research Report on Disseminated Neuroblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma IL-2, GD2Bi-aATC, GM-CSF - Disseminated Neuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Unknown | University of Virginia | 40 | 2014-11-01 | 2019-01-29 |
| Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant management of therapy complications, musculoskeletal complications management/prevention - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Withdrawn | Roswell Park Cancer Institute | 2012-05-01 | 2012-07-09 | |
| Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma diagnostic laboratory biomarker analysis - Disseminated Neuroblastoma, Localized Resectable Neuroblastoma | Completed | Children's Oncology Group | 90 | 2011-05-01 | 2015-05-12 | |
| Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant supersaturated calcium phosphate rinse, placebo, questionnaire administration - Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 226 | 2011-03-01 | 2019-09-17 |
| Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia cefepime hydrochloride - Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia | Phase 1 | Completed | Wake Forest University Health Sciences | 70 | 2011-02-01 | 2018-07-18 |
| Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload deferasirox - Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Terminated | City of Hope Medical Center | 1 | 2010-07-01 | 2019-06-18 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications internet-based intervention, questionnaire administration, psychosocial assessment and care - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 3 | Completed | Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | 1337 | 2008-08-01 | 2012-03-07 |
| Study of DNA in Blood Samples From Patients With Neuroblastoma laboratory biomarker analysis, polymerase chain reaction, polyacrylamide gel electrophoresis - Disseminated Neuroblastoma, Localized Resectable Neuroblastoma | Completed | Children's Oncology Group | 329 | 2007-06-01 | 2016-05-18 | |
| ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment ABT-751, quality-of-life assessment - Disseminated Neuroblastoma, Recurrent Neuroblastoma | Phase 2 | Completed | Children's Oncology Group | 92 | 2007-01-01 | 2019-07-17 |
| Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant lithium carbonate, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Completed | Fred Hutchinson Cancer Center | 20 | 2006-06-01 | 2017-03-07 |
| Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant etanercept, methylprednisolone - Accelerated Phase Chronic Myelogenous Leukemia, Blastic Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Children's Oncology Group | 39 | 2006-04-01 | 2017-09-29 |
| Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors tanespimycin, pharmacological study, laboratory biomarker analysis - Childhood Chronic Myelogenous Leukemia, Childhood Desmoplastic Small Round Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 70 | 2004-09-01 | 2013-06-04 |
| Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer ipilimumab, therapeutic allogeneic lymphocytes - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 | Completed | National Cancer Institute (NCI) | 21 | 2003-04-01 | 2013-03-27 |
| Pyrazoloacridine and Stem Cell or Bone Marrow Transplantation in Treating Young Patients With High-Risk Neuroblastoma pyrazoloacridine, filgrastim, autologous bone marrow transplantation - Disseminated Neuroblastoma, Recurrent Neuroblastoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 42 | 2002-12-01 | 2013-04-09 |
| R(+)XK469 in Treating Patients With Advanced Neuroblastoma R(+)XK469 - Disseminated Neuroblastoma, Localized Unresectable Neuroblastoma | Phase 1 | Completed | National Cancer Institute (NCI) | 85 | 2001-12-01 | 2013-12-16 |
| Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma monoclonal antibody Ch14.18, isotretinoin, aldesleukin - Disseminated Neuroblastoma, Recurrent Neuroblastoma | Phase 1 | Completed | National Cancer Institute (NCI) | 6 | 2001-01-01 | 2013-01-16 |
Neuroblastoma (14) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (10) · Burkitt Lymphoma (9) · Hodgkin Disease (7) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Leukemia, Myeloid, Acute (7) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (7) · Leukemia, Myelomonocytic, Chronic (7) · Leukemia, Neutrophilic, Chronic (7) · Lymphoma, Follicular (7) · Lymphoma, Large B-Cell, Diffuse (7) · Lymphoma, Large-Cell, Immunoblastic (7) · Lymphoma, Mantle-Cell (7) · Lymphoma, Non-Hodgkin (7) · Pdgfra-Associated Chronic Eosinophilic Leukemia (7)
Neoplasms by Histologic Type (17) · Neoplasms (16) · Neoplasms, Glandular and Epithelial (15) · Neoplasms, Germ Cell and Embryonal (14) · Neoplasms, Nerve Tissue (14) · Neoplasms, Neuroepithelial (14) · Neuroectodermal Tumors (14) · Neuroectodermal Tumors, Primitive (14) · Neuroectodermal Tumors, Primitive, Peripheral (13) · Hematologic Diseases (10) · Hemic and Lymphatic Diseases (10) · Immune System Diseases (10) · Immunoproliferative Disorders (10) · Leukemia (10) · Leukemia, Lymphoid (10)
Granulocyte-Macrophage Colony-Stimulating Factor (2) · Interleukin-2 (2) · Therapeutics (2) · aldesleukin (2) · sargramostim (2) · ABT751 (1) · Bone Marrow Transplantation (1) · CTLA-4 Antigen (1) · Cefepime (1) · Counseling (1) · Deferasirox (1) · E 7010 (1) · Electrophoresis, Polyacrylamide Gel (1) · Etanercept (1) · Filgrastim (1)
Children's Oncology Group (5) · National Cancer Institute (NCI) (5) · Fred Hutchinson Cancer Center (2) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1) · Roswell Park Cancer Institute (1) · University of Virginia (1) · Wake Forest University Health Sciences (1)
United States (16) · Canada (2) · Australia (1)
Aaron Sugalski, MD (1) · Andrew Gilman (1) · Anna Butturini (1) · Elizabeth Fox, MD (1) · Ewa Carrier (1) · Gregory Yanik, MD (1) · John Williamson (1) · Karen Syrjala (1) · Leona Holmberg (1) · Maxim Yankelevich (1) · Michael Hogarty, MD (1) · Nathaniel Treister, MD (1) · Paul Martin (1) · Philip McCarthy (1) · Susan Cohn (1)
PMID 18974373, PMID 28817727, PMID 32628342, PMID 33420905, PMID 33986124, PMID 36282798
U10CA098543 (3), P01CA081403 (1), P30CA022453 (1), R01CA093891 (1), R01CA112631 (1), U01CA069852 (1), U01CA069856 (1), U10CA095861 (1)