19 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 14 Not applicable, 5 Phase 3, 3 Phase 2, 1 Early Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 9, Unknown 3, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 5 | Completed 4, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Dentine Hypersensitivity: new trials by email Literature Review of Dentine Hypersensitivity trials Research Report on Dentine Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-Ceramic Strontium-doped bioactive glass-ceramic-filled dentine adhesive, Universal dentine adhesive - Dentine Hypersensitivity | Not applicable | Recruiting | The University of Hong Kong | 142 | 2026-06-16 | 2026-09-21 |
| Efficacy of Lasers, Propolis-Based Agent, and Sham for Dentine Hypersensitivity Nd:YAG Laser Application, Diode Laser Application, Herbal Propolis-Based Dentin Barrier Agent - Dentine Hypersensitivity | Not applicable | Completed | Ondokuz Mayıs University | 140 | 2025-12-15 | 2026-06-15 |
| Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization nano hydroxy apatite varnish Intervention (1), Potassium Nitrate Gel, Varnishes, Fluorid - Dentine Hypersensitivity | Not applicable | Not yet recruiting | Cairo University | 48 | 2025-07-10 | 2025-07-09 |
| Neurological Responses in Patients with Dentine Hypersensitivity Recording of brain activity using electroencephalography (EEG) - Dentine Hypersensitivity | Recruiting | Sheffield Teaching Hospitals NHS Foundation Trust | 60 | 2024-10-11 | 2024-10-09 | |
| Efficacy of Novel Titania Nanoparticles Enriched Mouth Wash in Treating Dentine Hypersensitivity Group- A Conventional Sensed Mouth Wash, Group-B Novel Titania nanoparticles enriched Mouth Wash - Dentine Hypersensitivity | Not applicable | Completed | Pakistan Institute of Medical Sciences | 130 | 2024-06-13 | 2025-02-04 |
| Managing Dentine Hypersensitivity With Silver Diamine Fluoride on Older Adults SDF, KNO3 - Dentine Hypersensitivity | Phase 2 | Unknown | The University of Hong Kong | 166 | 2023-02-01 | 2023-07-25 |
| Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes Sodium Monofluorophosphate, Stannous Fluoride, Nano-Hydroxyapatite - Dentine Hypersensitivity | Not applicable | Completed | Altinbas University | 48 | 2022-05-01 | 2024-01-09 |
| Efficacy of Miswak Extract Toothpaste as Compared Potassium Nitrate in The Management of Dentinal Hypersensitivity Miswak extract-containing toothpaste, Potassium nitrates-containing toothpaste, Placebo - Dentine Hypersensitivity | Not applicable | Unknown | Ministry of Health, Saudi Arabia | 96 | 2020-01-01 | 2019-11-29 |
| The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity mouthguard, mouthguard with desensitizing toothpaste - Dentine Hypersensitivity, Tooth Erosion | Not applicable | Completed | Khon Kaen University | 46 | 2018-06-18 | 2019-08-06 |
| A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity Dentin-Bonding Agents, Propolis - Dentine Hypersensitivity | Early Phase 1 | Completed | Dow University of Health Sciences | 52 | 2018-06-01 | 2021-02-15 |
| Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice - Dentine Hypersensitivity | Completed | Procter and Gamble | 1036 | 2018-01-08 | 2019-07-02 | |
| Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity 5% fluoride varnish, 8% arginine containing paste, Self-adhesive resin - Dentine Hypersensitivity | Phase 3 | Unknown | Aga Khan University | 60 | 2017-05-03 | 2018-06-29 |
| Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity UltraEZ, Enamelast - Hypersensitivity Dentin, Dentin Sensitivity | Not applicable | Unknown | Federal University of Uberlandia | 32 | 2017-03-20 | 2017-03-29 |
| Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment Potassium Oxalate 5%, Potassium Oxalate 10% - Dentin Sensitivity, Hypersensitivity Dentin | Not applicable | Unknown | Federal University of Uberlandia | 32 | 2017-03-14 | 2017-03-20 |
| Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity air puffs - Dentine Hypersensitivity | Completed | University of Zurich | 30 | 2015-07-01 | 2017-10-27 | |
| Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment Resin modified glass ionomer, Potassium Nitrate 2%, Low level laser therapy - Hypersensitivity Dentin, Dentin Sensitivity | Not applicable | Completed | Federal University of Uberlandia | 140 | 2014-10-01 | 2016-10-14 |
| Study to Investigate the Effect of Changes in Dentinal Hypersensitivity on Oral Health Parameters Test Toothpaste - Dentine Hypersensitivity | Not applicable | Completed | HALEON | 75 | 2013-08-27 | 2026-08-17 |
| Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment Colgate, Sensodyne, Nano P - Dentine Hypersensitivity | Not applicable | Completed | Federal University of São Paulo | 138 | 2013-04-01 | 2013-12-23 |
| Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity Stannous fluoride, Sodium monofluorophosphate - Dentine Hypersensitivity | Phase 3 | Completed | GlaxoSmithKline | 119 | 2013-02-01 | 2015-01-26 |
| Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity 5% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice, 0% calcium sodium phosphosilicate/sodium monofluorophosphate dentifrice, Sodium monofluorophosphate dentifrice - Dentine Hypersensitivity | Phase 2 | Completed | GlaxoSmithKline | 140 | 2012-08-01 | 2014-05-29 |
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Dentin Sensitivity (27) · Bites and Stings (1) · Hypersensitivity (1) · Tooth Erosion (1) · Toothache (1)
Stomatognathic Diseases (27) · Tooth Diseases (27) · Chemically-Induced Disorders (1) · Facial Pain (1) · Immune System Diseases (1) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Poisoning (1) · Signs and Symptoms (1) · Tooth Demineralization (1) · Tooth Wear (1) · Wounds and Injuries (1)
Tin Fluorides (5) · fluorophosphate (5) · Arginine (1) · CMW cement (1) · Calcium Carbonate (1) · Clinpro Sealant (1) · Dentin-Bonding Agents (1) · Low-Level Light Therapy (1) · Mouth Protectors (1) · Propolis (1) · Sensodyne (1) · Sodium Fluoride (1) · UltraEZ (1) · nano-hydroxyapatite-collagen (1) · potassium nitrate (1)
GlaxoSmithKline (7) · Federal University of Uberlandia (3) · HALEON (2) · The University of Hong Kong (2) · Aga Khan University (1) · Altinbas University (1) · Cairo University (1) · Dow University of Health Sciences (1) · Federal University of São Paulo (1) · Khon Kaen University (1) · Ministry of Health, Saudi Arabia (1) · Ondokuz Mayıs University (1) · Pakistan Institute of Medical Sciences (1) · Procter and Gamble (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1)
United States (7) · Brazil (4) · Pakistan (3) · China (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Germany (1) · Hong Kong (1) · Ireland (1) · Switzerland (1) · Thailand (1)
Abdulrahman Alshehri, MS (1) · Afsheen Mansoor, PhD (1) · Ather Akber, M.Sc (1) · Dominik Ettlin, MD,DMD (1) · Fiona Boissonade, BDS, PhD (1) · Hongchun Liu, Ph.D. (1) · Kemporn Kitsahawong, DDS,MSc,PhD (1) · Muhammad Hasan Hameed, BDS (1) · Olga D Flecha, PhD (1) · Paulo V Soares, DDS, MS, PHD (1) · Paulo V Soares, DDS,MS,PHD (1) · Paulo V Soares, PhD (1)
PMID 27093773, PMID 20370417, PMID 22385928, PMID 23248560, PMID 26437498, PMID 26694786, PMID 28652142, PMID 29789771, PMID 31415787, PMID 31592280, PMID 36286004, PMID 37454789, PMID 8295089