8 completed, 4 unknown. 12 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 8, Unknown 4 |
| Phase 2 | 5 | Completed 3, Unknown 2 |
Follow Dental Enamel Hypomineralization: new trials by email Literature Review of Dental Enamel Hypomineralization trials Research Report on Dental Enamel Hypomineralization
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH. In Vitro Study and In Situ Randomized Double-Blind Placebo Clinical Trial. Vitamin D3 mouth wash - Molar Incisor Hypomineralization | Phase 1 | Completed | Cairo University | 32 | 2024-08-30 | 2026-07-06 |
| Evaluation of Antimicrobial Photodynamic Therapy and Minimal Intervention Associated With Deproteinization in Permanent Teeth With Molar Incisor Hypomineralization Antimicrobial PDT and Papacarie Deproteinization, Conventional caries treatment, Antimicrobial PDT and 5% NaOCl Deproteinization - Hypomineralization Molar Incisor | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 69 | 2023-08-20 | 2023-11-28 |
| Articaine 4% Versus Lidocaine 2% for Local Anesthesia of MIH-affected Maxillary Molars Lidocaine 2%, Articaine 4% - Molar Incisor Hypomineralisation | Phase 1 / Phase 2 | Completed | Latakia University | 26 | 2022-10-17 | 2023-05-03 |
| Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy - Hypomineralization Molar Incisor | Phase 1 / Phase 2 | Completed | University of Nove de Julho | 50 | 2022-07-19 | 2024-10-03 |
| Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH Lidocaine 2%, Articaine 4% - Molar Incisor Hypomineralisation | Phase 1 / Phase 2 | Completed | Latakia University | 20 | 2022-01-22 | 2022-07-15 |
| Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization Hygiene Instructions, Sealant application, Low-level Laser - Dentin Sensitivity, Molar Incisor Hypomineralization | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 140 | 2021-01-01 | 2020-11-30 |
| Antimicrobial Photodynamic Therapy on Teeth With Molar Incisor Hypomineralization aPDT, ART - Molar Incisor Hypomineralization | Phase 1 | Unknown | University of Nove de Julho | 48 | 2019-08-01 | 2019-04-05 |
| Effect of Low-intensity Laser and Photodynamic Therapy on Infected Dentin of Permanent Teeth With MIH aPDT, ART - Molar Incisor Hypomineralization | Phase 1 | Completed | University of Nove de Julho | 48 | 2018-01-01 | 2019-03-22 |
| Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste - White Spot Lesion, Enamel Hypomineralization | Phase 1 | Unknown | Cairo University | 45 | 2017-07-01 | 2017-06-15 |
| Fluoride Bioavailability After Ingestion of Water or Foods Prepared With Fluoridated Water Meal prepared with non fluoridated water, Meal prepared with fluoridated water, Non fluoridated water - Dental Caries, Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 20 | 2013-01-01 | 2015-05-28 |
| Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes Toothpaste - Dental Caries, Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 24 | 2011-01-01 | 2013-10-28 |
| Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives Purified water, Fresh MFP/CaCO3 toothpaste, Fresh NaF/SiO2 toothpaste - Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 20 | 2011-01-01 | 2012-04-04 |
Molar Hypomineralization (8) · Fluorosis, Dental (3) · Dental Caries (2) · Dentin Sensitivity (1)
Congenital Abnormalities (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Developmental Defects of Enamel (12) · Stomatognathic Diseases (12) · Stomatognathic System Abnormalities (12) · Tooth Abnormalities (12) · Tooth Diseases (12) · Tooth Demineralization (2)
Low-Level Light Therapy (2) · Toothpastes (1)
University of Nove de Julho (5) · University of Campinas, Brazil (3) · Cairo University (2) · Latakia University (2)
Brazil (6) · Syria (2) · Egypt (1)
Livia MA Tenuta, PhD (3) · Mai Haidar, Dr (2) · Nabih Raslan, Dr (2) · Maha Swelam, Bachelor (1) · Parryhan M Abdelsamie, PhD (1)
PMID 23295625, PMID 31574879, PMID 33692185, PMID 37316315, PMID 37526883, PMID 38101830, PMID 40883469