5 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 11 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 5, Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Unknown 2 |
Follow Corneal Ulcer: new trials by email Literature Review of Corneal Ulcer trials Research Report on Corneal Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorometholone Study Adjunctive Topical Fluorometholone (FML) 0.1%, Standard Topical Antibiotic Therapy - Keratitis Bacterial, Corneal Ulcer (Diagnosis) | Phase 2 | Not yet recruiting | Vishal Jhanji | 174 | 2026-10-31 | 2026-06-10 |
| Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells Mesenchymal Stromal Cells, Control Solution - Corneal Ulcer | Phase 2 | Recruiting | University of Illinois Chicago | 38 | 2023-09-29 | 2026-11-04 |
| Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic Ulcers LV-Visio-AMTRIX - Corneal Ulcer, Persistent Corneal Epithelial Defect | Phase 2 | Withdrawn | TBF Genie Tissulaire | 2022-04-01 | 2022-08-05 | |
| Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers PXL Platinum 330 system + Riboflavin 0.25% TE Solution, Sham CXL + Artificial Tears - Keratitis, Corneal Ulcer | Phase 2 / Phase 3 | Unknown | Peschke GmbH | 488 | 2022-03-14 | 2022-10-28 |
| Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution, Standard of Care Therapy + Sham CXL + Artificial Tears - Keratitis, Corneal Ulcer | Phase 2 / Phase 3 | Unknown | Peschke GmbH | 468 | 2022-03-14 | 2022-10-28 |
| Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem Cells mesenchymal stem cells, limbal stem cells, standard treatment - Corneal Ulcer, Corneal Disease | Phase 1 / Phase 2 | Completed | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 25 | 2016-10-03 | 2020-07-30 |
| A Comparison of Three Fluoroquinolone Topical Eyedrops in the Treatment of Infectious Corneal Ulcers. Besivance 0.6% Ophthalmic Suspension, Zymaxid 0.5% Ophthalmic Solution, Vigamox 0.5% Ophthalmic Solution - Corneal Ulcers | Phase 2 | Terminated | Cornea Consultants Of Nashville | 2 | 2013-07-01 | 2015-08-13 |
| Collagen Cross-linking in Infectious Keratitis Trial Collagen cross-linking - Infectious Keratitis, Bacterial Keratitis | Phase 2 | Completed | Chulalongkorn University | 30 | 2013-03-01 | 2015-05-04 |
| Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. rhNGF 10 μg/ml, rhNGF 20 μg/ml, vehicle - Neurotrophic Keratitis, Keratitis | Phase 1 / Phase 2 | Completed | Dompé Farmaceutici S.p.A | 174 | 2013-01-01 | 2024-04-19 |
| Evaluation and Treatment of Eye Complications of Vaccinia Vaccination NP-016 Vaccine Immune Globulin (IV-VIG) - Vaccinia | Phase 2 | Completed | National Eye Institute (NEI) | 400 | 2004-04-19 | 2017-07-02 |
| A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers Povidone-Iodine - Infected Corneal Ulcers, Bacterial Keratitis | Phase 2 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 172 | 2002-11-01 | 2016-08-23 |
Keratitis (5) · Corneal Diseases (2) · Conjunctivitis (1) · Corneal Dystrophies, Hereditary (1) · Cowpox (1) · Disease (1) · Smallpox (1) · Vaccinia (1)
Eye Diseases (11) · Eye Infections (11) · Infections (11) · Corneal Diseases (9) · Keratitis (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Conjunctival Diseases (1) · DNA Virus Infections (1) · Eye Diseases, Hereditary (1) · Genetic Diseases, Inborn (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Poxviridae Infections (1) · Virus Diseases (1)
Lubricant Eye Drops (2) · Riboflavin (2) · Fluorometholone (1) · Gatifloxacin (1) · Moxifloxacin (1) · Ophthalmic Solutions (1) · Povidone-Iodine (1) · Solutions (1) · besifloxacin (1) · cenegermin (1)
Peschke GmbH (2) · Chulalongkorn University (1) · Cornea Consultants Of Nashville (1) · Dompé Farmaceutici S.p.A (1) · Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · National Eye Institute (NEI) (1) · TBF Genie Tissulaire (1) · University of Illinois Chicago (1) · Vishal Jhanji (1)
United States (7) · Belarus (1) · France (1) · Germany (1) · Italy (1) · Poland (1) · Spain (1) · Thailand (1) · United Kingdom (1)
Bala Ambati (2) · Yvette Viscuso (2) · Ali R Djalilian, MD (1) · Charlotte E Joslin, OD, PhD (1) · Francesco Sinigaglia, MD (1) · Igor Volotovski, Prof (1) · Ira A. Shivitz, M.D. (1) · Liudmila Marchenko, Prof (1) · Sherwin J. Isenberg, M.D. (1) · Vishal Jhanji, MD (1) · Zinaida Kvacheva (1)