27 completed, 6 recruiting, 6 unknown, 2 not yet recruiting. 35 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 35 | Completed 22, Recruiting 6, Unknown 4, Not yet recruiting 2, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Class II Malocclusion: new trials by email Literature Review of Class II Malocclusion trials Research Report on Class II Malocclusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion Infrazygomatic Crest Miniscrews - Class II Malocclusion | Not applicable | Recruiting | Mansoura University | 16 | 2026-09-15 | 2026-10-20 |
| Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy clear aligners, traditional treatment Fixed appliances with class II elastics. - Malocclusion, Class II Malocclusion | Not applicable | Recruiting | Hama University | 24 | 2026-08-25 | 2026-09-16 |
| The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life CTB, CMA - CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion | Not applicable | Not yet recruiting | Aslam Alkadhimi | 88 | 2026-03-01 | 2025-12-18 |
| Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion. Head gear activator, Twin Block, Invisalign mandibular advancement - Class II Malocclusion, Class II Malocclusion, Division 1 | Not applicable | Not yet recruiting | Vastra Gotaland Region | 144 | 2026-01-15 | 2026-02-11 |
| Effects of Different Anchorage Methods and Low-Level Laser Therapy in Power Bar Distalization Power Bar Distalization Appliance, Mandibular Miniscrew Anchorage, Mandibular Orthodontic Button Anchorage - Class II Malocclusion | Not applicable | Completed | TC Erciyes University | 57 | 2025-09-10 | 2026-10-22 |
| Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II MARA appliance, fixed twin block - Class II Malocclusion, Mandibular Deficiency | Not applicable | Recruiting | Mansoura University | 60 | 2025-04-27 | 2026-01-14 |
| Ready-made vs. Custom-made Carriere Motion Appliance Custom-made Carriere motion appliance, Ready-made Carriere motion appliance - Class II Malocclusion | Not applicable | Recruiting | Mansoura University | 24 | 2025-01-13 | 2026-01-22 |
| Evaluation of Diagnostic Accuracy of Artificial Intelligence in Treatment Planning for Non-growing Class II Cases Class II Malocclusion | Unknown | Cairo University | 193 | 2025-01-01 | 2025-01-27 | |
| Maxillary Segmental Distalization Using Digitally Printed Appliances maxillary segmental distalization - Class II Malocclusion | Not applicable | Unknown | Mansoura University | 40 | 2024-04-12 | 2025-05-30 |
| Comparison of Distalization of Maxillary First and Second Molars Between a Miniscrew Implant Supported Device and Clear Aligners. Upper molar distalization - Distalization, Class II Malocclusion | Not applicable | Recruiting | Aristotle University Of Thessaloniki | 40 | 2024-04-10 | 2025-06-27 |
| Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion Twin Block - Class II Malocclusion | Completed | Al-Azhar University | 20 | 2024-04-01 | 2026-08-31 | |
| Evaluation of Maxillary Molar Distalization With Two Bone Supported Protocols Using Cone Beam Computed Tomography Fast Back Rapid Distalizer, Modified Leaf Spring Self-Activated Expander - Class II Malocclusion | Not applicable | Completed | Tanta University | 20 | 2024-03-10 | 2026-08-04 |
| Invisalign® System with Mandibular Advancement Invisalign® System with mandibular advancement featuring occlusal blocks - Class II Malocclusion, Mandibular Advancement | Not applicable | Recruiting | Align Technology, Inc. | 36 | 2024-02-14 | 2024-10-23 |
| Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes Twin Block - Class II Malocclusion | Phase 1 | Completed | Al-Azhar University | 20 | 2024-01-01 | 2026-09-01 |
| Comparing the Impact of Rubber Bands on Teeth Straightening with Clear Aligners Versus Traditional Braces: a Clinical Study clear aligners and elastics, class 2 elastics - Class II Malocclusion, IMPA Angle | Not applicable | Completed | University of Rome Tor Vergata | 40 | 2023-09-01 | 2025-02-18 |
| Modified Herbst Approach to Improve Chin Projection Modified Herbst Approach, Conventional Herbst Approach - Class II Malocclusion | Not applicable | Withdrawn | University of Alberta | 2023-08-25 | 2025-08-06 | |
| Comparison Of The Effects Of Clear Aligners And Twinblock Appliances In Functional Treatment Of Class II Malocclusion Invisalign Clear Aligners, Twinblock Functional Appliance - Class II Malocclusion, Mandibular Retrognathism | Not applicable | Completed | Bezmialem Vakif University | 34 | 2023-08-01 | 2026-03-06 |
| Effectiveness of Modified Functional Appliance With Expander Modified twin block appliance with expander, Conventional twin block appliance with expander - Class II Malocclusion | Not applicable | Unknown | University of Baghdad | 48 | 2023-05-09 | 2023-11-07 |
| TADs Anchored vs Conventional Anchored Carriere Motion Appliance Carriere Motion Appliance - Class II Malocclusion | Not applicable | Completed | Al-Azhar University | 20 | 2023-01-01 | 2024-07-03 |
| The Effect of Low-level Laser Therapy on Functional Treatment of Skeletal Class II Patients twin block, twin block combined with low level laser - Class II Malocclusion | Not applicable | Completed | Mansoura University | 24 | 2022-10-26 | 2024-03-13 |
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Overbite (43) · Malocclusion (3) · Malocclusion, Angle Class II (3) · Malocclusion, Angle Class III (2) · Pain (2) · Dentofacial Deformities (1) · Micrognathism (1) · Retrognathia (1)
Stomatognathic Diseases (43) · Tooth Diseases (43) · Malocclusion (40) · Malocclusion, Angle Class II (40) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Craniofacial Abnormalities (2) · Jaw Abnormalities (2) · Jaw Diseases (2) · Maxillofacial Abnormalities (2) · Musculoskeletal Abnormalities (2) · Musculoskeletal Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2)
Low-Level Light Therapy (4) · Orthodontic Appliances, Fixed (3) · Blood Grouping and Crossmatching (1) · Dental Implants (1) · Electric Stimulation Therapy (1) · Observation (1) · Piezosurgery (1)
Al-Azhar University (7) · Damascus University (7) · Mansoura University (7) · Future University in Egypt (3) · Bezmialem Vakif University (2) · Cairo University (2) · Academy of Interdisciplinary Dental Education and Research (1) · Ain Shams University (1) · Align Technology, Inc. (1) · Aristotle University Of Thessaloniki (1) · Aslam Alkadhimi (1) · Fundación Universitaria CIEO (1) · Hama University (1) · Istanbul Medipol University Hospital (1) · TC Erciyes University (1)
Egypt (19) · Syria (8) · Turkey (Türkiye) (4) · Canada (2) · Greece (1) · Iraq (1) · Ireland (1) · Italy (1) · Pakistan (1) · Poland (1) · Sweden (1)
Doa'a Tahseen Alfailany, DDS (2) · Mohammad Y Hajeer, DDS MSc PhD (2) · Mohammad Y. Hajeer, DDS,MSc,PhD (2) · Mudar Mohammad Mousa, DDS (2) · Abubakr M Fouad (1) · Afifa Ehsan, B.D.S (1) · Ahmed M Fouda (1) · Ahsen Irem Toktas, Research Assistant (1) · Anna Westerlund, Professor (1) · Aslam Alkadhimi (1) · Asmaa A Elabd, master (1) · Ayyaz Ali Khan, Ph. D (1) · Carlos Flores Mir, DSc (1)
PMID 39316889, PMID 39805909, PMID 39840371, PMID 40708614, PMID 41152368, PMID 41692591, PMID 41814309