5 completed. 5 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 5 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow Chorioamnionitis: new trials by email Literature Review of Chorioamnionitis trials Research Report on Chorioamnionitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis Unasyn, Ampicillin/gentamicin - Chorioamnionitis | Phase 2 / Phase 3 | Completed | Stanford University | 92 | 2009-05-01 | 2018-05-18 |
| Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Ampicillin + gentamicin - Chorioamnionitis, Puerperal Endometritis | Phase 2 / Phase 3 | Completed | Hospital de Santa Maria, Portugal | 161 | 2008-10-01 | 2016-11-28 |
| Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio) N-acetylcysteine, Control - Chorioamnionitis, Brain Injury | Phase 1 / Phase 2 | Completed | Medical University of South Carolina | 46 | 2008-08-01 | 2021-04-12 |
| N-acetylcysteine in Intra-amniotic Infection/Inflammation amniocentesis, N-acetylcysteine or placebo - Labor, Premature, Preterm Premature Rupture of the Membranes | Phase 1 / Phase 2 | Completed | Ohio State University | 68 | 2006-10-01 | 2018-10-10 |
| Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy oral versus vaginal metronidazole - Vaginosis, Bacterial, Premature Birth | Phase 2 | Completed | Centers for Disease Control and Prevention | 126 | 1999-10-01 | 2024-05-29 |
Birth Weight (1) · Brain Injuries (1) · Endometritis (1) · Fetal Membranes, Premature Rupture (1) · Infections (1) · Inflammation (1) · Neonatal Sepsis (1) · Obstetric Labor, Premature (1) · Premature Birth (1) · Preterm Premature Rupture of the Membranes (1) · Vaginosis, Bacterial (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Fetal Diseases (5) · Obstetric Labor Complications (5) · Placenta Diseases (5) · Pregnancy Complications (5) · Urogenital Diseases (5) · Fetal Membranes, Premature Rupture (4) · Pathological Conditions, Signs and Symptoms (3) · Female Urogenital Diseases (2) · Genital Diseases (2) · Genital Diseases, Female (2) · Infections (2) · Pathologic Processes (2) · Adnexal Diseases (1)
Acetylcysteine (2) · Ampicillin (2) · Gentamicins (2) · Amniocentesis (1) · Sodium Chloride (1) · sultamicillin (1)
Centers for Disease Control and Prevention (1) · Hospital de Santa Maria, Portugal (1) · Medical University of South Carolina (1) · Ohio State University (1) · Stanford University (1)
United States (4) · Portugal (1)
Catalin S Buhimschi, MD, MBA (1) · Dorothea D. Jenkins, MD (1) · Eugene Chang, MD (1) · Filipa Faria Vaz Passos, Dr (1) · Jane E Hitti, MD, MPH (1) · Natali Aziz, MD (1)
PMID 23090521, PMID 25064164, PMID 26545726
R01NS052448 (1)